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NEUROIMMUNOLOGY
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Primarily devoted to the research in Multiple Sclerosis (MS), the Laboratory of neuroimmunology studies the interaction between the immune response - with a focus on innate immunity and CD8+ T cells - and environmental factors. The Lab team is also trying to understand the interaction between the new monoclonal antibody for MS treatment, natalizumab, and the biology of JC virus, the agent of progressive multifocal leukoencephalopathy (PML).
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Finally, together with clinicians, the Laboratory holds a research program dealing with the neurocognitive disorders in HIV+ patients. Read more ...
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Renaud A. Du Pasquier, M.D.
Associate Professor Complete list of publications 2011-present:
Associate Professor, Médecin adjoint
Head of the Laboratory of neuroimmunology
Division of Neurology, Dpt of clinical neurosciences and
Division of Immunology and Allergy, Dpt of internal medicine, CHUV, Lausanne.
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2005-2011:
Assistant Professor, Médecin associé
Divisions of Neurology and of Immunology and Allergy, CHUV, Lausanne. September 2007-June 2008:
Acting Chairman in the Division of Neurology, CHUV, Lausanne. 2005:
Recipient of the Swiss National Foundation Professorship. 1999-2004:
Post-doc, then Instructor (Neurology and Division of Viral Pathogenesis, Prof. I.J. Koralnik), BIDMC, Harvard Medical School, Boston Massachusetts, USA. Research project: "Study of the role of CD8+ T cells in Progressive Multifocal Leukoencephalopathy, a demyelinating disease of the central nervous system caused by the polyomavirus JC". 2004:
Board-certified in Internal Medicine. 2001:
Board-certified in Neurology. 1997:
Thesis in Medicine, University of Geneva. 1992:
Diploma of Medicine, University of Geneva.
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Amandine Mathias, Ph.D.
Postdoctoral Fellow 2012-present:
Post-doctoral Fellow, Division of Immunology and Allergy, CHUV, Lausanne.
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2008-2011:
PhD entitled "Secretory IgA and intestinal epithelial cells at the interface between homeostasis regulation and protection against infection"
R&D laboratory, Division of Immunology and Allergy, CHUV, Lausanne. 2008:
AgroParisTech Engineer Master in Sciences for Biological Industries
Engineer School Master thesis entitled: Inflammatory responses induced after interaction between Toll like receptors and bacterial toxins.
Research Laboratory Pierre FABRE, Toulouse, France. 2007:
Diploma work entitled: Comparative genomics of wheat and barley powdery mildew fungi.
John Innes Centre, Norwich, UK. 2007:
Internship work entitled: Construction of a library of Erwinia amylovora mutants and enrichment in mutant of interest.
INRA, Paris, France.
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Guillaume Perriard
Ph.D. Student May 2011-present:
PhD thesis entitled "Characterization of IL-26: a new player in the pathogenesis of multiple sclerosis ?", Division of Immunology and Allergy, CHUV, Lausanne.
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2009-2011:
Master of Science in Biology, major Microbiology and Immunology, ETH Zürich, Prof. A. Oxenius. 2006-2009:
Bachelor of Science in Biology (minor : Biochemistry), University of Fribourg, Prof. F. Müller.
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Samanta Simioni
Medical Assistant in neuropsychology 2005-present:
Medical Assistant in neuropsychology, Division of Neurology, CHUV, Lausanne.
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2004:
DESS in Clinical Psychology, University of Geneva. 2002:
Master in Psychology, University of Geneva.
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Mathieu Canales
Technician 2008-present:
Technician, Division of Immunology and Allergy, CHUV, Lausanne.
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2008:
Lab Assistant in Biology in the "laboratoire des liquides biologiques", HUG Geneva. 2004-2007:
Lab Assistant in Biology Apprenticeship, Agroscope Changins-Wädenswil ACW, Nyon.
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Awards:
- 2010:
Faculty Price 2010 (Faculty of Biology and Medicine - FBM, University of Lausanne) for the E. Jaquiéry's work entitled: "Intrathecal immune response to EBV in early MS" published in European Journal of Immunology.
- 2009:
Best Poster in Basic Clinical Research at the Annual Congress of the Swiss Society for Allergology and Immunology 2009, Geneva. Increased EBV Reactivation in the Cerebrospinal Fluid of Patients with Early Multiple Sclerosis
(E. Jaquiéry, first author, R. Du Pasquier, last author).
- 2008:
First BIOGEN DOMPE award for Clinical Research into Multiple Sclerosis
(S. Jilek, first author and R. Du Pasquier, last author).
- 2007:
Recipient of the Abbott prize for the second best project submitted to the Swiss HIV Cohort Study in 2006
(R. Du Pasquier, principal investigator).
Past project's Collaborators
Valeriy PARFENOV (to October 2012)
Samantha JILEK TERRASSE (to March 2012)
Caroline ANTONIOL (to December 2011)
Malela KALUBI (to December 2011)
Joanna LE BOUDEZ (to December 2011)
Sonia NEGRO (to February 2011)
Emilie JAQUIERY (to February 2010)
Andreas LYSANDROPOULOS (to September 2009)
Laurence GUIGNARD (to July 2008)
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