Denise Nardelli Haefliger Lab

Denise Nardelli Haefliger, PhD, Assistant Professor
++41(0)21-3144081
denise.nardelli-haefliger@chuv.ch

Research topics

Mucosal vaccine strategies against human papillomavirus and cervical cancer

Cervical cancer is the second leading cause of cancer deaths in women worldwide, and virtually all of these tumors are attributable to infection with a sub-set of human papillomaviruses (HPV), of which HPV16 is found most frequently.

Our research group is involved in the development of prophylactic and therapeutic vaccines able to prevent and treat HPV infections and associated cancer lesions in the anogenital tract. We are primarily interested in vaccination strategies that generate immune effector responses in the genital mucosa. In particular we develop live vaccine with attenuated Salmonella. Our projects include pre-clinical studies in mice and clinical studies in healthy volunteers and in patients.

Other activities

We collaborate with WHO in the development of a global HPV laboratory network (see WHO HPV reference laboratory)

Selected publications