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Accueil > Recherche > Axes de recherche > L'immunité innée, l'épigénétique et le métabolisme > Sélection des publications

Sélection des publications

Ciarlo E, Heinonen T, Théroude C, Herderschee J, Mombelli M, Lugrin J, Pfefferlé M, Tyrrell B, Lensch S, Acha-Orbea H, Le Roy D, Auwerx J, Roger T. Sirtuin 2 deficiency increases bacterial phagocytosis by macrophages and protects from chronic staphylococcal infection. Front Immunol. 2017 Aug 28;8:1037.


Roger T, Schneider A, Weier M, Sweep FC, Le Roy D, Bernhagen J, Calandra T, Giannoni E. High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E997-1005.

Savva A, Brouwer MC, Roger T, Valls Serón M, Le Roy D, Ferwerda B, van der Ende A, Bochud PY, van de Beek D, Calandra T. Functional polymorphisms of macrophage migration inhibitory factor as predictors of morbidity and mortality of pneumococcal meningitis. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3597-602.

Meller S, Di Domizio J, Voo KS, Friedrich HC, Chamilos G, Ganguly D, Conrad C, Gregorio J, Le Roy D, Roger T, Ladbury JE, Homey B, Watowich S, Modlin RL, Kontoyiannis DP, Liu YJ, Arold ST, Gilliet M. T(H)17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26. Nat Immunol. 2015 Sep;16(9):970-9.

Roger T., Lugrin J., Le Roy D., Goy G., Mombelli M., Koessler T., Ding X.C., Chanson A.-L., Reymond M.K., Miconnet I., Schrenzel J., François P., Calandra T. Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection. Blood 2011, 117; 1205-1217.

Roger T., Froidevaux C., Le Roy D., Knaup Reymond M., Chanson A.-L., Mauri D., Burns K., Riederer B., Akira S., Calandra T. Protection from severe Gram-negative sepsis by targeting Toll-like receptor 4 (TLR4). Proc. Natl. Acad. Sci. U.S.A. 2009, 106: 2348-52.

Calandra T., Roger T. Macrophage migration inhibitory factor: a regulator of innate immunity. Nature Reviews Immunol 2003, 3:791-800.

Roger T., David J., Glauser M.P., Calandra T. MIF regulates innate immune responses through modulation of Toll-like receptor 4. Nature 2001, 414:920-24.