Les activités du CHUV
des maladies infectieuses
Accueil > Recherche > Axes de recherche > Immunité innée et épigénétique > Sélection des publications

Sélection des publications

Lugrin J., Ciarlo E., Santos A., Grandmaison G., dos Santos I., Le Roy D., Roger T. The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock. Biochim Biophys Acta. 2013, 1833:1498-510.

Ciarlo E., Savva A., Roger T. Epigenetic in sepsis: targeting histone deacetylases (HDACs). Int J Antimicrob Agents. 2013, 42 Suppl:S8-12.

Roger T., Lugrin J., Le Roy D., Goy G., Mombelli M., Koessler T., Ding X.C., Chanson A.-L., Reymond M.K., Miconnet I., Schrenzel J., François P., Calandra T. Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection. Blood 2011, 117; 1205-1217.

Mombelli M., Lugrin J., Rubino I., Chanson A.-L., Giddey M., Calandra T., Roger T. Histone deacetylase inhibitors impair antibacterial defenses of macrophages. J Infect Dis. 2011, 204:1367-74.

Roger T., Froidevaux C., Le Roy D., Knaup Reymond M., Chanson A.-L., Mauri D., Burns K., Riederer B., Akira S., Calandra T. Protection from severe Gram-negative sepsis by targeting Toll-like receptor 4 (TLR4). Proc. Natl. Acad. Sci. U.S.A. 2009, 106: 2348-52.

Calandra T., Roger T. Macrophage migration inhibitory factor: a regulator of innate immunity. Nature Reviews Immunol 2003, 3:791-800.

Roger T., David J., Glauser M.P., Calandra T. MIF regulates innate immune responses through modulation of Toll-like receptor 4. Nature 2001, 414:920-24.