Publications

2020

Phase 1 HIV vaccine trial to evaluate the safety and immunogenicity of HIV subtype C DNA and MF59-adjuvanted subtype C Env protein.

Hosseinipour MC, Innes C, Naidoo S, Mann P, Hutter J, Ramjee G, Sebe M, Maganga L, Herce ME, deCamp AC, Marshall K, Dintwe O, Andersen-Nissen E, Tomaras GD, Mkhize N, Morris L, Jensen R, Miner MD, Pantaleo G, Ding S, Van Der Meeren O, Barnett SW, McElrath

Clin Infect Dis. 2020 Jan 4

2019

Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector.

Giel-Moloney M, Esteban M, Oakes BH, Vaine M, Asbach B, Wagner R, Mize GJ, Spies AG, McElrath J, Perreau M, Roger T, Ives A, Calandra T, Weiss D, Perdiguero B, Kibler KV, Jacobs B, Ding S, Tomaras GD, Montefiori DC, Ferrari G, Yates NL, Roederer M, Kao SF

Sci Rep. 2019 Dec 27;9(1):20005

Human gut microbiota is associated with HIV-reactive immunoglobulin at baseline and following HIV vaccination.

Cram JA, Fiore-Gartland AJ, Srinivasan S, Karuna S, Pantaleo G, Tomaras GD, Fredricks DN, Kublin JG

PLoS One. 2019;14(12):e0225622

Heterologous Combination of VSV-GP and NYVAC Vectors Expressing HIV-1 Trimeric gp145 Env as Vaccination Strategy to Induce Balanced B and T Cell Immune Responses.

Perdiguero B, Gómez CE, García-Arriaza J, Sánchez-Corzo C, Sorzano CÓS, Wilmschen S, von Laer D, Asbach B, Schmalzl C, Peterhoff D, Ding S, Wagner R, Kimpel J, Levy Y, Pantaleo G, Esteban M

Front Immunol. 2019;10:2941

Neurologic complications of acute hepatitis E virus infection.

Ripellino P, Pasi E, Melli G, Staedler C, Fraga M, Moradpour D, Sahli R, Aubert V, Martinetti G, Bihl F, Bernasconi E, Terziroli Beretta-Piccoli B, Cerny A, Dalton HR, Zehnder C, Mathis B, Zecca C, Disanto G, Kaelin-Lang A, Gobbi C

Neurol Neuroimmunol Neuroinflamm. 2020 Jan;7(1)

A Robust Method for Assaying the Immunoreactive Fraction in Nonequilibrium Systems.

Denoël T, Pedrelli L, Pantaleo G, Prior JO

Pharmaceuticals (Basel). 2019 Dec 3;12(4)

The complex challenges of HIV vaccine development require renewed and expanded global commitment.

Bekker LG, Tatoud R, Dabis F, Feinberg M, Kaleebu P, Marovich M, Ndung'u T, Russell N, Johnson J, Luba M, Fauci AS, Morris L, Pantaleo G, Buchbinder S, Gray G, Vekemans J, Kim JH, Levy Y, Corey L, Shattock R, Makanga M, Williamson C, Dieffenbach C, Gooden

Lancet. 2019 Dec 2

Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity.

Katsuyama T, Li H, Comte D, Tsokos GC, Moulton VR

J Clin Invest. 2019 Dec 2;129(12):5411-5423

Predictive factors of severe infections in patients with systemic necrotizing vasculitides: data from 733 patients enrolled in five randomized controlled trials of the French Vasculitis Study Group.

Lafarge A, Joseph A, Pagnoux C, Puéchal X, Cohen P, Samson M, Hamidou M, Karras A, Quemeneur T, Ribi C, Groh M, Mouthon L, Guillevin L, Terrier B

Rheumatology (Oxford). 2019 Nov 28

Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Antisense Protein (ASP) RNA Transcripts in Patients by Strand-Specific RT-PCR.

Mancarella A, Procopio FA, Achsel T, De Crignis E, Foley BT, Corradin G, Bagni C, Pantaleo G, Graziosi C

J Vis Exp. 2019 Nov 27;(153)

Risk of malignancy in patients treated for systemic necrotising vasculitis.

Lafarge A, Joseph A, Pagnoux C, Puechal X, Cohen P, Samson M, Hamidou M, Karras A, Groh M, Quemeneur T, Ribi C, Mouthon L, Guillevin L, Terrier B, French Vasculitis Study Group (FVSG).

Ann Rheum Dis. 2019 Nov 25

Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis.

Friebus-Kardash J, Trendelenburg M, Eisenberger U, Ribi C, Chizzolini C, Huynh-Do U, Lang KS, Wilde B, Kribben A, Witzke O, Dolff S, Hardt C

BMC Nephrol. 2019 Nov 21;20(1):430

Antigenic competition in CD4+ T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial.

Kallas EG, Grunenberg NA, Yu C, Manso B, Pantaleo G, Casapia M, Baden LR, Valencia J, Sobieszczyk M, Van Tieu H, Allen M, Hural J, Graham BS, Kublin J, Gilbert PB, Corey L, Goepfert PA, McElrath MJ, Johnson RP, Huang Y, Frahm N

Sci Transl Med. 2019 Nov 20;11(519)

A model for reticular dysgenesis shows impaired sensory organ development and hair cell regeneration linked to cellular stress.

Rissone A, Jimenez E, Bishop K, Carrington B, Slevin C, Wincovitch SM, Sood R, Candotti F, Burgess SM

Dis Model Mech. 2019 Nov 14

Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.

Pinto D, Fenwick C, Caillat C, Silacci C, Guseva S, Dehez F, Chipot C, Barbieri S, Minola A, Jarrossay D, Tomaras GD, Shen X, Riva A, Tarkowski M, Schwartz O, Bruel T, Dufloo J, Seaman MS, Montefiori DC, Lanzavecchia A, Corti D, Pantaleo G, Weissenhorn W

Cell Host Microbe. 2019 Nov 13;26(5):623-637.e8

Anti-C1q Antibodies as Occurring in Systemic Lupus Erythematosus Could Be Induced by an Epstein-Barr Virus-Derived Antigenic Site.

Csorba K, Schirmbeck LA, Tuncer E, Ribi C, Roux-Lombard P, Chizzolini C, Huynh-Do U, Vanhecke D, Trendelenburg M

Front Immunol. 2019;10:2619

Nonvascularized human skin chronic allograft rejection.

Rotman S, Koch N, Wiesner L, Aubert V, Rosales IA, Colvin RB, Raffoul W, Pascual M

Am J Transplant. 2019 Nov;19(11):3191-3196

T-cell exhaustion in HIV infection.

Fenwick C, Joo V, Jacquier P, Noto A, Banga R, Perreau M, Pantaleo G

Immunol Rev. 2019 Nov;292(1):149-163

Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8+ T lymphocyte exhaustion.

Ascione A, Arenaccio C, Mallano A, Flego M, Gellini M, Andreotti M, Fenwick C, Pantaleo G, Vella S, Federico M

BMC Biotechnol. 2019 Oct 17;19(1):67

Correction for Kibler et al., "Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC".

Kibler KV, Asbach B, Perdiguero B, García-Arriaza J, Yates NL, Parks R, Stanfield-Oakley S, Ferrari G, Montefiori DC, Tomaras GD, Roederer M, Foulds KE, Forthal DN, Seaman MS, Self S, Gottardo R, Phogat S, Tartaglia J, Barnett S, Cristillo AD, Weiss D, Ga

J Virol. 2019 Nov 1;93(21)

Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial.

Pantaleo G, Janes H, Karuna S, Grant S, Ouedraogo GL, Allen M, Tomaras GD, Frahm N, Montefiori DC, Ferrari G, Ding S, Lee C, Robb ML, Esteban M, Wagner R, Bart PA, Rettby N, McElrath MJ, Gilbert PB, Kublin JG, Corey L, NIAID HIV Vaccine Trials Network.

Lancet HIV. 2019 Oct 7

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial.

Rouphael NG, Morgan C, Li SS, Jensen R, Sanchez B, Karuna S, Swann E, Sobieszczyk ME, Frank I, Wilson GJ, Tieu HV, Maenza J, Norwood A, Kobie J, Sinangil F, Pantaleo G, Ding S, McElrath MJ, De Rosa SC, Montefiori DC, Ferrari G, Tomaras GD, Keefer MC, HVTN

J Clin Invest. 2019 Sep 30

Management of allergy transfer upon solid organ transplantation.

Muller YD, Vionnet J, Beyeler F, Eigenmann P, Caubet JC, Villard J, Berney T, Scherer K, Spertini F, Peter Fricker M, Lang C, Schmid-Grendelmeier P, Benden C, Roux Lombard P, Aubert V, Immer F, Pascual M, Harr T, Swiss Transplant Cohort Study.

Am J Transplant. 2019 Sep 18

Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania.

Mkindi CG, Marandu EA, Masawa N, Bani F, Nyuri A, Byakuzana T, Klimkait T, Ding S, Pantaleo G, Battegay M, Orlova-Fink N, Weisser-Rohacek M, Daubenberger C

BMC Res Notes. 2019 Sep 6;12(1):561

Anti-apolipoprotein A-1 autoantibodies correlate with disease activity in systemic lupus erythematosus.

Nigolian H, Ribi C, Courvoisier DS, Pagano S, Alvarez M, Trendelenburg M, Huynh-Do U, Vuilleumier N, Dayer JM, Chizzolini C, Roux-Lombard P

Rheumatology (Oxford). 2019 Aug 3

Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement.

Banga R, Rebecchini C, Procopio FA, Noto A, Munoz O, Ioannidou K, Fenwick C, Ohmiti K, Cavassini M, Corpataux JM, de Leval L, Pantaleo G, Perreau M

PLoS Pathog. 2019 Jul;15(7):e1007918

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART.

Bachmann N, von Siebenthal C, Vongrad V, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Fellay J, Roth V, Kok YL, Thorball CW, Borghesi A, Parbhoo S, Wieser M, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Rauch A, Hoffmann M, Bernasconi E, Cavassi

Nat Commun. 2019 Jul 19;10(1):3193

Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells.

Niven J, Madelon N, Page N, Caruso A, Harlé G, Lemeille S, Seemayer CA, Hugues S, Gannagé M

Cell Rep. 2019 Jul 2;28(1):21-29.e6

Efficacy and Adverse Events During Janus Kinase Inhibitor Treatment of SAVI Syndrome.

Volpi S, Insalaco A, Caorsi R, Santori E, Messia V, Sacco O, Terheggen-Lagro S, Cardinale F, Scarselli A, Pastorino C, Moneta G, Cangemi G, Passarelli C, Ricci M, Girosi D, Derchi M, Bocca P, Diociaiuti A, El Hachem M, Cancrini C, Tomà P, Granata C, Ravel

J Clin Immunol. 2019 Jul;39(5):476-485

Novel Nanofluidic IgE Assay versus a Reference Method: A Real-World Comparison.

Roethlisberger S, Karoui O, Mapelli D, Audran R, Aubert V, Girard LD, Rebeaud F, Leimgruber A, Buss G, Duc J, Langner-Viviani F, Maerki I, Spertini F

Int Arch Allergy Immunol. 2019 Jun 12:1-9

The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes.

Hill DL, Pierson W, Bolland DJ, Mkindi C, Carr EJ, Wang J, Houard S, Wingett SW, Audran R, Wallin EF, Jongo SA, Kamaka K, Zand M, Spertini F, Daubenberger C, Corcoran AE, Linterman MA

J Exp Med. 2019 Jun 7

Corrigendum to "A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles" [Virology 507 (2017) 242-256].

Meador LR, Kessans SA, Kilbourne J, Kibler KV, Pantaleo G, Esteban M, Blattman JN, Jacobs BL, Mor TS

Virology. 2019 Jun 6

Successful desensitization to pomalidomide in a patient with POEMS syndrome with delayed-type hypersensitivity to immunomodulatory imid drugs.

Grandoni F, Stalder G, Borgeat Kaeser A, Ribi C, Cairoli A, Blum S

Leuk Lymphoma. 2019 Jun 4:1-3

Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway.

Fenwick C, Loredo-Varela JL, Joo V, Pellaton C, Farina A, Rajah N, Esteves-Leuenberger L, Decaillon T, Suffiotti M, Noto A, Ohmiti K, Gottardo R, Weissenhorn W, Pantaleo G

J Exp Med. 2019 May 23

[Side effects of immune checkpoint inhibitors: diagnosis and management].

Perrinjaquet C, Zaher M, Ferraro DA, Comte D, Trueb L, Zimmermann S, Coukos G, Orcurto A

Rev Med Suisse. 2019 May 15;15(651):1010-1016

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance.

Martins F, Sofiya L, Sykiotis GP, Lamine F, Maillard M, Fraga M, Shabafrouz K, Ribi C, Cairoli A, Guex-Crosier Y, Kuntzer T, Michielin O, Peters S, Coukos G, Spertini F, Thompson JA, Obeid M

Nat Rev Clin Oncol. 2019 May 15

The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis.

Wyss A, Raselli T, Perkins N, Ruiz F, Schmelczer G, Klinke G, Moncsek A, Roth R, Spalinger MR, Hering L, Atrott K, Lang S, Frey-Wagner I, Mertens JC, Scharl M, Sailer AW, Pabst O, Hersberger M, Pot C, Rogler G, Misselwitz B

Mucosal Immunol. 2019 May;12(3):733-745

Multi-arm, multi-stage randomised controlled trials for evaluating therapeutic HIV cure interventions.

Moore CL, Stöhr W, Crook AM, Richert L, Leliévre JD, Pantaleo G, García F, Vella S, Lévy Y, Thiébaut R, McCormack S

Lancet HIV. 2019 May;6(5):e334-e340

Gene therapy for Wiskott-Aldrich syndrome: here to stay.

Candotti F

Lancet Haematol. 2019 May;6(5):e230-e231

HIV transmission chains exhibit greater HLA-B homogeneity than randomly expected.

Nguyen H, Thorball CW, Fellay J, Böni J, Yerly S, Perreau M, Klimkait T, Kusjeko K, Bachmann N, Chaudron SE, Paioni P, Thurnheer MC, Battegay M, Cavassini M, Vernazza P, Bernasconi E, Günthard HF, Kouyos R, Swiss HIV Cohort Study.

J Acquir Immune Defic Syndr. 2019 Apr 29

[Autoimmune disorders during chronic human immunodeficiency virus (HIV) infection].

Filippidis P, Comte D

Rev Med Suisse. 2019 Apr 3;15(645):723-731

[Allergy to fish].

Mahdi Aljedani R, Ribi C

Rev Med Suisse. 2019 Apr 3;15(645):706-709

Davantage de silence.

Seebach J, Spertini F

Rev Med Suisse. 2019 Apr 3;15(645):703-704

[From isolated cutaneous vasculitis to systemic disease : a diagnostic approach to purpura in the adult patient].

Horisberger A, Ghosn J, Di Lucca J, Comte D

Rev Med Suisse. 2019 Apr 3;15(645):713-718

Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting.

Julg B, Dee L, Ananworanich J, Barouch DH, Bar K, Caskey M, Colby DJ, Dawson L, Dong KL, Dubé K, Eron J, Frater J, Gandhi RT, Geleziunas R, Goulder P, Hanna GJ, Jefferys R, Johnston R, Kuritzkes D, Li JZ, Likhitwonnawut U, van Lunzen J, Martinez-Picado J,

Lancet HIV. 2019 Apr;6(4):e259-e268

The Fatigue Assessment Scale as a simple and reliable tool in systemic lupus erythematosus: a cross-sectional study.

Horisberger A, Courvoisier D, Ribi C

Arthritis Res Ther. 2019 Mar 25;21(1):80

Detection of antisense protein (ASP) RNA transcripts in individuals infected with human immunodeficiency virus type 1 (HIV-1).

Mancarella A, Procopio FA, Achsel T, De Crignis E, Foley BT, Corradin G, Bagni C, Pantaleo G, Graziosi C

J Gen Virol. 2019 Mar 21

Treatment of chronic non-infectious uveitis and scleritis.

Rossi DC, Ribi C, Guex-Crosier Y

Swiss Med Wkly. 2019 Feb 25;149:w20025

Emergence of drug resistance in the Swiss HIV Cohort Study under potent antiretroviral therapy is observed in socially disadvantaged patients.

Abela IA, Scherrer AU, Böni J, Yerly S, Klimkait T, Perreau M, Hirsch HH, Furrer H, Calmy A, Schmid P, Cavassini M, Bernasconi E, Günthard HF, Swiss HIV Cohort Study.

Clin Infect Dis. 2019 Mar 7

Appropriate thiamin pyrophosphate levels are required for acclimation to changes in photoperiod.

Rosado-Souza L, Proost S, Moulin M, Bergmann S, Bocobza S, Aharoni A, Fitzpatrick TB, Mutwil M, Fernie AR, Obata T

Plant Physiol. 2019 Mar 5

A systematic phylogenetic approach to study the interaction of HIV-1 with coinfections, non-communicable and opportunistic diseases.

Kusejko K, Bachmann N, Chaudron SE, Nguyen H, Braun DL, Hampel B, Battegay M, Bernasconi E, Calmy A, Cavassini M, Hoffmann M, Böni J, Yerly S, Klimkait T, Perreau M, Rauch A, Günthard HF, Kouyos RD, Swiss HIV Cohort Study.

J Infect Dis. 2019 Mar 4

Viral diversity from next-generation sequencing of HIV-1 samples provides precise estimates of infection recency and time since infection.

Carlisle LA, Turk T, Kusejko K, Metzner KJ, Leemann C, Schenkel C, Bachmann N, Posada S, Beerenwinkel N, Böni J, Yerly S, Klimkait T, Perreau M, Braun DL, Rauch A, Calmy A, Cavassini M, Battegay M, Vernazza P, Bernasconi E, Günthard HF, Kouyos RD, Swiss H

J Infect Dis. 2019 Mar 4

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals.

Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy JP, Sékaly RP, Chomont N

Nat Commun. 2019 Feb 18;10(1):814

High Number of Potential Transmitters Revealed in a Population-based Systematic Hepatitis C Virus RNA Screening Among Human Immunodeficiency Virus-infected Men Who Have Sex With Men.

Braun DL, Hampel B, Martin E, Kouyos R, Kusejko K, Grube C, Flepp M, Stöckle M, Conen A, Béguelin C, Schmid P, Delaloye J, Rougemont M, Bernasconi E, Rauch A, Günthard HF, Böni J, Fehr JS, Swiss HIV Cohort Study .

Clin Infect Dis. 2019 Feb 1;68(4):561-568

Patterns of care for Multiple Sclerosis in a setting of universal care access: A cross-sectional study.

Barin L, Kaufmann M, Salmen A, Kamm CP, Gobbi C, Kuhle J, Pot C, Chan A, Czaplinski A, Ajdacic-Gross V, Rodgers S, Kesselring J, Puhan MA, von Wyl V, Swiss Multiple Sclerosis Registry.

Mult Scler Relat Disord. 2019 Feb;28:17-25

High Cure Rates With Grazoprevir-Elbasvir With or Without Ribavirin Guided by Genotypic Resistance Testing Among Human Immunodeficiency Virus/Hepatitis C Virus-coinfected Men Who Have Sex With Men.

Braun DL, Hampel B, Kouyos R, Nguyen H, Shah C, Flepp M, Stöckle M, Conen A, Béguelin C, Künzler-Heule P, Nicca D, Schmid P, Delaloye J, Rougemont M, Bernasconi E, Rauch A, Günthard HF, Böni J, Fehr JS, Swiss HIV Cohort Study .

Clin Infect Dis. 2019 Feb 1;68(4):569-576

Re-boost immunizations with the peptide-based therapeutic HIV vaccine, Vacc-4x, restores geometric mean viral load set-point during treatment interruption.

Rockstroh JK, Asmuth D, Pantaleo G, Clotet B, Podzamczer D, van Lunzen J, Arastéh K, Mitsuyasu R, Peters B, Silvia N, Jolliffe D, Ökvist M, Krogsgaard K, Sommerfelt MA

PLoS One. 2019;14(1):e0210965

[Where are we with oral immunotherapy for food allergy ?]

Borgeat Kaeser A, Moi L, Spertini F

Rev Med Suisse. 2019 Jan 9;15(N° 632-633):20-22

[Side effects of cancer immunotherapies : important role for the clinical immunologist].

Obeid M

Rev Med Suisse. 2019 Jan 9;15(N° 632-633):17-19

[Risk of treatment failure and therapeutic novelties in asthma].

Horisberger A, Mahdi Aljedani R, Spertini F, Ribi C

Rev Med Suisse. 2019 Jan 9;15(N° 632-633):23-26

New therapeutic perspectives to manage refractory immune checkpoint-related toxicities.

Martins F, Sykiotis GP, Maillard M, Fraga M, Ribi C, Kuntzer T, Michielin O, Peters S, Coukos G, Spertini F, Thompson JA, Obeid M

Lancet Oncol. 2019 Jan;20(1):e54-e64

Comparative analysis and generation of a robust HIV-1 DNA quantification assay.

Thomas J, Ruggiero A, Procopio FA, Pantaleo G, Paxton WA, Pollakis G

J Virol Methods. 2019 Jan;263:24-31

Signaling Lymphocytic Activation Molecule Family Member 1 Engagement Inhibits T Cell-B Cell Interaction and Diminishes Interleukin-6 Production and Plasmablast Differentiation in Systemic Lupus Erythematosus.

Karampetsou MP, Comte D, Suárez-Fueyo A, Katsuyama E, Yoshida N, Kono M, Kyttaris VC, Tsokos GC

Arthritis Rheumatol. 2019 Jan;71(1):99-108

2018

A severe case of refractory esophageal stenosis induced by nivolumab and responding to tocilizumab therapy.

Horisberger A, La Rosa S, Zurcher JP, Zimmermann S, Spertini F, Coukos G, Obeid M

J Immunother Cancer. 2018 Dec 27;6(1):156

HIV Infection Functionally Impairs Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses.

Amelio P, Portevin D, Hella J, Reither K, Kamwela L, Lweno O, Tumbo A, Geoffrey L, Ohmiti K, Ding S, Pantaleo G, Daubenberger C, Perreau M

J Virol. 2018 Dec 12

PERISCOPE: road towards effective control of pertussis.

PERISCOPE Consortium.

Lancet Infect Dis. 2018 Nov 28

Importance of routine viral load monitoring: higher levels of resistance at ART failure in Uganda and Lesotho compared with Switzerland.

Bachmann N, von Braun A, Labhardt ND, Kadelka C, Günthard HF, Sekaggya-Wiltshire C, Castelnuovo B, Kambugu A, Lejone TI, Böni J, Yerly S, Perreau M, Klimkait T, Kouyos RD, Fehr J, Swiss HIV Cohort Study .

J Antimicrob Chemother. 2018 Nov 21

Antibodies to Chlamydia trachomatis and reproductive health issues in women with SLE: a case-control study.

Santos A, Greub G, Aeby S, Wunder D, Pantaleo G, Ribi C

Lupus Sci Med. 2018;5(1):e000293

Replication-competent NYVAC-KC yields improved immunogenicity to HIV-1 antigens in rhesus macaques, compared to non-replicating NYVAC.

J Virol. 2018 Nov 14

Priming with a potent HIV-1 DNA vaccine frames the quality of immune responses prior to a poxvirus and protein boost.

Asbach B, Kibler KV, Köstler J, Perdiguero B, Yates NL, Stanfield-Oakley S, Tomaras GD, Kao SF, Foulds KE, Roederer M, Seaman MS, Montefiori DC, Parks R, Ferrari G, Forthal DN, Phogat S, Tartaglia J, Barnett SW, Self SG, Gottardo R, Cristillo AD, Weiss DE

J Virol. 2018 Nov 14

Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines.

Perriot S, Mathias A, Perriard G, Canales M, Jonkmans N, Merienne N, Meunier C, El Kassar L, Perrier AL, Laplaud DA, Schluep M, Déglon N, Du Pasquier R

Stem Cell Reports. 2018 Nov 13;11(5):1199-1210

Signaling lymphocyte activation molecule family in systemic lupus erythematosus.

Comte D, Karampetsou MP, Humbel M, Tsokos GC

Clin Immunol. 2018 Nov 8

Supplemental parenteral nutrition improves immunity with unchanged carbohydrate and protein metabolism in critically ill patients: The SPN2 randomized tracer study.

Berger MM, Pantet O, Jacquelin-Ravel N, Charrière M, Schmidt S, Becce F, Audran R, Spertini F, Tappy L, Pichard C

Clin Nutr. 2018 Nov 5

Prospective evaluation of the capillaroscopic skin ulcer risk index in systemic sclerosis patients in clinical practice: a longitudinal, multicentre study.

Walker UA, Jaeger VK, Bruppacher KM, Dobrota R, Arlettaz L, Banyai M, Beron J, Chizzolini C, Groechenig E, Mueller RB, Spertini F, Villiger PM, Distler O

Arthritis Res Ther. 2018 Oct 25;20(1):239

A severe case of neuro-Sjögren's syndrome induced by pembrolizumab.

Ghosn J, Vicino A, Michielin O, Coukos G, Kuntzer T, Obeid M

J Immunother Cancer. 2018 Oct 22;6(1):110

Effect of national HIV testing recommendations and local interventions on HIV testing practices in a Swiss university hospital: a retrospective analysis between 2012 and 2015.

Lazzarino T, Martenet S, Mamin R, Du Pasquier RA, Peters S, Perreau M, Muller O, Hugli O, Cavassini M, Darling KEA

BMJ Open. 2018 Oct 3;8(10):e021203

Autoantibodies Against Albumin in Patients With Systemic Lupus Erythematosus.

Nehring J, Schirmbeck LA, Friebus-Kardash J, Dubler D, Huynh-Do U, Chizzolini C, Ribi C, Trendelenburg M

Front Immunol. 2018;9:2090

Immunogenicity and safety of double versus standard dose of the seasonal influenza vaccine in solid-organ transplant recipients: A randomized controlled trial.

Mombelli M, Rettby N, Perreau M, Pascual M, Pantaleo G, Manuel O

Vaccine. 2018 Oct 1;36(41):6163-6169

TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs.

Cheng L, Wang Q, Li G, Banga R, Ma J, Yu H, Yasui F, Zhang Z, Pantaleo G, Perreau M, Zurawski S, Zurawski G, Levy Y, Su L

J Clin Invest. 2018 Oct 1;128(10):4387-4396

Efficient B cell Depletion With Rituximab Despite Massive Proteinuria.

Halfon M, Pascual M, Aubert V, Rotman S, Yannick MD

Transplantation. 2018 Oct;102(10):e401-e402

The disease burden of Multiple Sclerosis from the individual and population perspective: Which symptoms matter most?

Barin L, Salmen A, Disanto G, Babačić H, Calabrese P, Chan A, Kamm CP, Kesselring J, Kuhle J, Gobbi C, Pot C, Puhan MA, von Wyl V, Swiss Multiple Sclerosis Registry (SMSR).

Mult Scler Relat Disord. 2018 Oct;25:112-121

Association of antibodies against myelin and neuronal antigens with neuroinflammation in systemic lupus erythematosus.

Pröbstel AK, Thanei M, Erni B, Lecourt AC, Branco L, André R, Roux-Lombard P, Koenig KF, Huynh-Do U, Ribi C, Chizzolini C, Kappos L, Trendelenburg M, Derfuss T

Rheumatology (Oxford). 2018 Sep 27

Tracing HIV-1 strains that imprint broadly neutralizing antibody responses.

Kouyos RD, Rusert P, Kadelka C, Huber M, Marzel A, Ebner H, Schanz M, Liechti T, Friedrich N, Braun DL, Scherrer AU, Weber J, Uhr T, Baumann NS, Leemann C, Kuster H, Chave JP, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, A

Nature. 2018 Sep;561(7723):406-410

[Primary biliary cholangitis : an update].

Vieira Barbosa J, Vionnet J, Sciarra A, Sempoux C, Aubert V, Moradpour D, Fraga Christinet M

Rev Med Suisse. 2018 Aug 29;14(616):1489-1494

Benefit of Bet v 1 contiguous overlapping peptide immunotherapy persists during first follow-up season.

Kettner A, DellaCorte G, de Blay F, Jacobsen L, Jutel M, Worm M, Charlon V, Simonsen K, Reymond C, Spertini F

J Allergy Clin Immunol. 2018 Aug;142(2):678-680.e7

[Hemophagocytic Lymphohistiocytosis].

Stalder G, Ribi C, Duchosal MA

Praxis (Bern 1994). 2018 Aug;107(16):902-911

Quantifying the drivers of HIV transmission and prevention in men who have sex with men: a population model-based analysis in Switzerland.

Kusejko K, Marzel A, Hampel B, Bachmann N, Nguyen H, Fehr J, Braun DL, Battegay M, Bernasconi E, Calmy A, Cavassini M, Hoffmann M, Böni J, Yerly S, Klimkait T, Perreau M, Rauch A, Günthard HF, Kouyos RD, Swiss HIV Cohort Study.

HIV Med. 2018 Nov;19(10):688-697

IRF5 Is a Key Regulator of Macrophage Response to Lipopolysaccharide in Newborns.

Schneider A, Weier M, Herderschee J, Perreau M, Calandra T, Roger T, Giannoni E

Front Immunol. 2018;9:1597

CD32+ and PD-1+ Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals.

Noto A, Procopio FA, Banga R, Suffiotti M, Corpataux JM, Cavassini M, Fenwick C, Gottardo R, Perreau M, Pantaleo G

J Virol. 2018 Oct 15;92(20)

Effect of high-intensity versus low-intensity praziquantel treatment on HIV disease progression in HIV and Schistosoma mansoni co-infected patients: a randomised controlled trial.

Abaasa A, Asiki G, Obuku Ekii A, Wanyenze J, Pala P, J van Dam G, L A M Corstjens P, Hughes P, Ding S, Pantaleo G, Kaleebu P, M Elliott A, Kamali A

Wellcome Open Res. 2018;3:81

The Candidate Blood Stage Malaria Vaccine P27A Induces a Robust Humoral Response in a Fast Track to the Field Phase I Trial in Exposed and Non Exposed Volunteers.

Steiner-Monard V, Kamaka K, Karoui O, Roethlisberger S, Audran R, Daubenberger C, Fayet-Mello A, Erdmann-Voisin A, Felger I, Geiger K, Govender L, Houard S, Huber E, Mayor C, Mkindi C, Portevin D, Rusch S, Schmidlin S, Tiendrebeogo RW, Theisen M, Thierry

Clin Infect Dis. 2018 Jun 26

Hyperglycaemia is inversely correlated with live M. bovis BCG-specific CD4+ T cell responses in Tanzanian adults with latent or active tuberculosis.

Boillat-Blanco N, Tumbo AN, Perreau M, Amelio P, Ramaiya KL, Mganga M, Schindler C, Gagneux S, Reither K, Probst-Hensch N, Pantaleo G, Daubenberger C, Portevin D

Immun Inflamm Dis. 2018 Jun;6(2):345-353

The Cumulative Impact of Harm Reduction on the Swiss HIV Epidemic: Cohort Study, Mathematical Model, and Phylogenetic Analysis.

Marzel A, Kusejko K, Weber R, Bruggmann P, Rauch A, Roth JA, Bernasconi E, Calmy A, Cavassini M, Hoffmann M, Böni J, Yerly S, Klimkait T, Perreau M, Günthard HF, Kouyos RD, Swiss HIV Cohort Study .

Open Forum Infect Dis. 2018 May;5(5):ofy078

Eosinophilic esophagitis: latest insights from diagnosis to therapy.

Schoepfer A, Blanchard C, Dawson H, Lucendo A, Mauro A, Ribi C, Safroneeva E, Savarino EV, Penagini R

Ann N Y Acad Sci. 2018 May 15

Churg-Strauss syndrome with cardiac involvement: case illustration and contribution of CMR in the diagnosis and clinical follow-up.

d'Ersu E, Ribi C, Monney P, Vincenti G, Schwitter J, Rotman S, Hullin R, Regamey J

Int J Cardiol. 2018 May 1;258:321-324

[Sublingual immunotherapy for the treatment of allergic rhinoconjonctivitis and asthma : a practical approach].

Ghosn J, Spertini F, Comte D

Rev Med Suisse. 2018 Apr 4;14(601):735-739

[Seasonal allergic rhinitis].

Salvadé I, Moi L, Ribi C, Spertini F

Rev Med Suisse. 2018 Apr 4;14(601):726-730

HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.

Yates NL, deCamp AC, Korber BT, Liao HX, Irene C, Pinter A, Peacock J, Harris LJ, Sawant S, Hraber P, Shen X, Rerks-Ngarm S, Pitisuttithum P, Nitayapan S, Berman PW, Robb ML, Pantaleo G, Zolla-Pazner S, Haynes BF, Alam SM, Montefiori DC, Tomaras GD

J Virol. 2018 Apr 15;92(8)

Immunogenicity of NYVAC Prime-Protein Boost Human Immunodeficiency Virus Type 1 Envelope Vaccination and Simian-Human Immunodeficiency Virus Challenge of Nonhuman Primates.

Saunders KO, Santra S, Parks R, Yates NL, Sutherland LL, Scearce RM, Balachandran H, Bradley T, Goodman D, Eaton A, Stanfield-Oakley SA, Tartaglia J, Phogat S, Pantaleo G, Esteban M, Gomez CE, Perdiguero B, Jacobs B, Kibler K, Korber B, Montefiori DC, Fer

J Virol. 2018 Apr 15;92(8)

Comparison of CyTOF assays across sites: Results of a six-center pilot study.

Leipold MD, Obermoser G, Fenwick C, Kleinstuber K, Rashidi N, McNevin JP, Nau AN, Wagar LE, Rozot V, Davis MM, DeRosa S, Pantaleo G, Scriba TJ, Walker BD, Olsen LR, Maecker HT

J Immunol Methods. 2018 Feb;453:37-43

Clinical Manifestations and Pathophysiological Mechanisms of the Wiskott-Aldrich Syndrome.

Candotti F

J Clin Immunol. 2018 Jan;38(1):13-27

2017

High titers of ADAbs in rheumatic disease patients undergoing anti-TNF therapy is not associated with lupus-like autoimmunity.

Safran A, Perreau M, So A, Zufferey P

Lupus. 2017 Dec;26(14):1571-1572

Sequential Vacc-4x and romidepsin during combination antiretroviral therapy (cART): Immune responses to Vacc-4x regions on p24 and changes in HIV reservoirs.

Tapia G, Højen JF, Ökvist M, Olesen R, Leth S, Nissen SK, VanBelzen DJ, O'Doherty U, Mørk A, Krogsgaard K, Søgaard OS, Østergaard L, Tolstrup M, Pantaleo G, Sommerfelt MA

J Infect. 2017 Dec;75(6):555-571

Therapeutic intranasal instillation of allergen-loaded microbubbles suppresses experimental allergic asthma in mice.

Corthésy B, Bioley G

Biomaterials. 2017 Oct;142:41-51

Tocilizumab for giant cell arteritis with corticosteroid-resistant progressive anterior ischemic optic neuropathy.

Vionnet J, Buss G, Mayer C, Sokolov AA, Borruat FX, Spertini F

Joint Bone Spine. 2017 Oct;84(5):615-619

Targeted Immune Interventions for an HIV-1 Cure.

Perreau M, Banga R, Pantaleo G

Trends Mol Med. 2017 Oct;23(10):945-961

Cell-Mediated Immune Predictors of Vaccine Effect on Viral Load and CD4 Count in a Phase 2 Therapeutic HIV-1 Vaccine Clinical Trial.

Huang Y, Pantaleo G, Tapia G, Sanchez B, Zhang L, Trondsen M, Hovden AO, Pollard R, Rockstroh J, Ökvist M, Sommerfelt MA

EBioMedicine. 2017 Oct;24:195-204

Mining for pairs: shared clinic visit dates identify steady HIV-positive partnerships.

Marzel A, Shilaih M, Turk T, Campbell NK, Yang WL, Böni J, Yerly S, Klimkait T, Aubert V, Furrer H, Calmy A, Battegay M, Cavassini M, Bernasconi E, Schmid P, Metzner KJ, Günthard HF, Kouyos RD, Swiss HIV Cohort Study (SHCS).

HIV Med. 2017 Oct;18(9):667-676

The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes.

Merienne N, Vachey G, de Longprez L, Meunier C, Zimmer V, Perriard G, Canales M, Mathias A, Herrgott L, Beltraminelli T, Maulet A, Dequesne T, Pythoud C, Rey M, Pellerin L, Brouillet E, Perrier AL, du Pasquier R, Déglon N

Cell Rep. 2017 Sep 19;20(12):2980-2991

Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis.

Turk T, Bachmann N, Kadelka C, Böni J, Yerly S, Aubert V, Klimkait T, Battegay M, Bernasconi E, Calmy A, Cavassini M, Furrer H, Hoffmann M, Günthard HF, Kouyos RD, Swiss HIV Cohort Study., Aubert V, Battegay M, Bernasconi E, Böni J, Braun DL, Bucher HC, C

Elife. 2017 Sep 12;6

Gas-filled microbubbles: Novel mucosal antigen-delivery system for induction of anti-pathogen's immune responses in the gut.

Corthésy B, Bioley G

Gut Microbes. 2017 Sep 3;8(5):511-519

Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania.

Amelio P, Portevin D, Reither K, Mhimbira F, Mpina M, Tumbo A, Nickel B, Marti H, Knopp S, Ding S, Penn-Nicholson A, Darboe F, Ohmiti K, Scriba TJ, Pantaleo G, Daubenberger C, Perreau M

PLoS Negl Trop Dis. 2017 Jul;11(7):e0005817

SIgA-Shigella Immune Complexes Interact with Dectin-1 and SIGNR3 to Differentially Regulate Mouse Peyer's Patch and Mesenteric Lymph Node Dendritic Cell's Responsiveness.

Mikulic J, Bioley G, Corthésy B

J Mol Biol. 2017 Jul 21;429(15):2387-2400

Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis.

Aguilo N, Gonzalo-Asensio J, Alvarez-Arguedas S, Marinova D, Gomez AB, Uranga S, Spallek R, Singh M, Audran R, Spertini F, Martin C

Nat Commun. 2017 Jul 14;8:16085

A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles.

Meador LR, Kessans SA, Kilbourne J, Kibler KV, Pantaleo G, Roderiguez ME, Blattman JN, Jacobs BL, Mor TS

Virology. 2017 Jul;507:242-256

Exploring the effect of vitamin D3 supplementation on the anti-EBV antibody response in relapsing-remitting multiple sclerosis.

Rolf L, Muris AH, Mathias A, Du Pasquier R, Koneczny I, Disanto G, Kuhle J, Ramagopalan S, Damoiseaux J, Smolders J, Hupperts R

Mult Scler. 2018 Sep;24(10):1280-1287

Parent-offspring regression to estimate the heritability of an HIV-1 trait in a realistic setup.

Bachmann N, Turk T, Kadelka C, Marzel A, Shilaih M, Böni J, Aubert V, Klimkait T, Leventhal GE, Günthard HF, Kouyos R, Swiss HIV Cohort Study.

Retrovirology. 2017 May 23;14(1):33

Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients.

Cooper AR, Lill GR, Shaw K, Carbonaro-Sarracino DA, Davila A, Sokolic R, Candotti F, Pellegrini M, Kohn DB

Blood. 2017 May 11;129(19):2624-2635

Increased ex vivo antigen presentation profile of B cells in multiple sclerosis.

Mathias A, Perriard G, Canales M, Soneson C, Delorenzi M, Schluep M, Du Pasquier RA

Mult Scler. 2017 May;23(6):802-809

Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency.

Shaw KL, Garabedian E, Mishra S, Barman P, Davila A, Carbonaro D, Shupien S, Silvin C, Geiger S, Nowicki B, Smogorzewska EM, Brown B, Wang X, de Oliveira S, Choi Y, Ikeda A, Terrazas D, Fu PY, Yu A, Fernandez BC, Cooper AR, Engel B, Podsakoff G, Balamurug

J Clin Invest. 2017 May 1;127(5):1689-1699

B-cell abnormalities and impact on antibody response in HIV infection.

Noto A, Pantaleo G

Curr Opin HIV AIDS. 2017 May;12(3):203-208

Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses.

Zurawski G, Shen X, Zurawski S, Tomaras GD, Montefiori DC, Roederer M, Ferrari G, Lacabaratz C, Klucar P, Wang Z, Foulds KE, Kao SF, Yu X, Sato A, Yates NL, LaBranche C, Stanfield-Oakley S, Kibler K, Jacobs B, Salazar A, Self S, Fulp W, Gottardo R, Galmin

J Virol. 2017 May 1;91(9)

HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Specific B

García-Arriaza J, Perdiguero B, Heeney JL, Seaman MS, Montefiori DC, Yates NL, Tomaras GD, Ferrari G, Foulds KE, Roederer M, Self SG, Borate B, Gottardo R, Phogat S, Tartaglia J, Barnett SW, Burke B, Cristillo AD, Weiss DE, Lee C, Kibler KV, Jacobs BL, Wa

J Virol. 2017 May 1;91(9)

The Presence of Human Immunodeficiency Virus-Associated Neurocognitive Disorders Is Associated With a Lower Adherence to Combined Antiretroviral Treatment.

Kamal S, Locatelli I, Wandeler G, Sehhat A, Bugnon O, Metral M, Du Pasquier R, Gutbrod K, Cavassini M, Schneider MP, and the Swiss HIV Cohort Study.

Open Forum Infect Dis. 2017 Spring;4(2):ofx070

Disponibilité de la désensibilisation en allergologie aujourd’hui : étape ou tournant historique ?

Harr T, Spertini F, Seebach J

Rev Med Suisse. 2017 Apr 5;13(557):731-732

[Next generation sequencing : a diagnostic tool for inherited immune defects].

Droz-Georget S, Riccio O, Royer-Bertrand B, Superti-Furga A, Candotti F

Rev Med Suisse. 2017 Apr 5;13(557):763-766

[Transient hypogammaglobulinemia of infancy].

Bellutti Enders F, Conti F, Candotti F, Angelini F

Rev Med Suisse. 2017 Apr 5;13(557):739-742

Identification of a novel HLA-B18 allele, B18:119, using sequence-based typing in a caucasoid individual.

André C, Pantaleo G, Aubert V

HLA. 2017 Apr;89(4):244-245

Safety, tolerability and efficacy of intradermal rabies immunization with DebioJect™.

Vescovo P, Rettby N, Ramaniraka N, Liberman J, Hart K, Cachemaille A, Piveteau LD, Zanoni R, Bart PA, Pantaleo G

Vaccine. 2017 Mar 27;35(14):1782-1788

Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies.

Petrovas C, Ferrando-Martinez S, Gerner MY, Casazza JP, Pegu A, Deleage C, Cooper A, Hataye J, Andrews S, Ambrozak D, Del Río Estrada PM, Boritz E, Paris R, Moysi E, Boswell KL, Ruiz-Mateos E, Vagios I, Leal M, Ablanedo-Terrazas Y, Rivero A, Gonzalez-Hern

Sci Transl Med. 2017 Jan 18;9(373)

[Innovations in the treatment of severe asthma].

Buss G, Spertini F

Rev Med Suisse. 2017 Jan 11;13(544-545):18-19

[Hope for chronic inflammatory diseases : the anti-IL-6 receptor monoclonal antibody tocilizumab].

Spertini F

Rev Med Suisse. 2017 Jan 11;13(544-545):20-22

EBI2 Expression and Function: Robust in Memory Lymphocytes and Increased by Natalizumab in Multiple Sclerosis.

Clottu AS, Mathias A, Sailer AW, Schluep M, Seebach JD, Du Pasquier R, Pot C

Cell Rep. 2017 Jan 3;18(1):213-224

2016

Elevated serum levels of free interleukin-18 in adult-onset Still's disease.

Girard C, Rech J, Brown M, Allali D, Roux-Lombard P, Spertini F, Schiffrin EJ, Schett G, Manger B, Bas S, Del Val G, Gabay C

Rheumatology (Oxford). 2016 Dec;55(12):2237-2247

Blockade of C5 in Severe Acute Postinfectious Glomerulonephritis Associated With Anti-Factor H Autoantibody.

Chehade H, Rotman S, Frémeaux-Bacchi V, Aubert V, Sadallah S, Sifaki L, Salomon R, Pascual M

Am J Kidney Dis. 2016 Dec;68(6):944-948

Rituximab versus fingolimod after natalizumab in multiple sclerosis: Also consider progressive multifocal leukoencephalopathy risk.

Marignier R, Durand-Dubief F, du Pasquier R, Vukusic S

Ann Neurol. 2016 Nov;80(5):791

The long terminal repeat negative control region is a critical element for insertional oncogenesis after gene transfer into hematopoietic progenitors with Moloney murine leukemia viral vectors.

Ikawa Y, Uchiyama T, Jagadeesh GJ, Candotti F

Gene Ther. 2016 Nov;23(11):815-818

Determinants of HIV-1 broadly neutralizing antibody induction.

Rusert P, Kouyos RD, Kadelka C, Ebner H, Schanz M, Huber M, Braun DL, Hozé N, Scherrer A, Magnus C, Weber J, Uhr T, Cippa V, Thorball CW, Kuster H, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J,

Nat Med. 2016 Nov;22(11):1260-1267

Therapeutic vaccines and immunological intervention in HIV infection: a paradigm change.

Pantaleo G, Levy Y

Curr Opin HIV AIDS. 2016 Nov;11(6):576-584

A Direct Comparison of Two Densely Sampled HIV Epidemics: The UK and Switzerland.

Ragonnet-Cronin ML, Shilaih M, Günthard HF, Hodcroft EB, Böni J, Fearnhill E, Dunn D, Yerly S, Klimkait T, Aubert V, Yang WL, Brown AE, Lycett SJ, Kouyos R, Brown AJ

Sci Rep. 2016 Sep 19;6:32251

Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs.

Oberle CS, Joos B, Rusert P, Campbell NK, Beauparlant D, Kuster H, Weber J, Schenkel CD, Scherrer AU, Magnus C, Kouyos R, Rieder P, Niederöst B, Braun DL, Pavlovic J, Böni J, Yerly S, Klimkait T, Aubert V, Trkola A, Metzner KJ, Günthard HF, Swiss HIV Coho

Retrovirology. 2016 Sep 5;13(1):62

Unite forces to validate biomarkers in the quest for lasting HIV remission.

Rokx C, Vella S, Pantaleo G, Lévy Y, Boucher CA

AIDS. 2016 Jul 17;30(11):1859-60

Efficacy of a therapeutic treatment using gas-filled microbubble-associated phospholipase A2 in a mouse model of honeybee venom allergy.

Corthésy B, Lassus A, Terrettaz J, Tranquart F, Bioley G

Allergy. 2016 Jul;71(7):957-66

Current approaches to assess HIV-1 persistence.

Banga R, Procopio FA, Perreau M

Curr Opin HIV AIDS. 2016 Jul;11(4):424-31

PD-1(+) and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals.

Banga R, Procopio FA, Noto A, Pollakis G, Cavassini M, Ohmiti K, Corpataux JM, de Leval L, Pantaleo G, Perreau M

Nat Med. 2016 Jul;22(7):754-61

Effect of Schistosoma mansoni Infection on Innate and HIV-1-Specific T-Cell Immune Responses in HIV-1-Infected Ugandan Fisher Folk.

Obuku AE, Asiki G, Abaasa A, Ssonko I, Harari A, van Dam GJ, Corstjens PL, Joloba M, Ding S, Mpendo J, Nielsen L, Kamali A, Elliott AM, Pantaleo G, Kaleebu P, Pala P

AIDS Res Hum Retroviruses. 2016 Jul;32(7):668-75

Genotypic Resistance Tests Sequences Reveal the Role of Marginalized Populations in HIV-1 Transmission in Switzerland.

Shilaih M, Marzel A, Yang WL, Scherrer AU, Schüpbach J, Böni J, Yerly S, Hirsch HH, Aubert V, Cavassini M, Klimkait T, Vernazza PL, Bernasconi E, Furrer H, Günthard HF, Kouyos R, Swiss HIV Cohort Study.

Sci Rep. 2016 Jun 14;6:27580

Clinically-relevant threshold of preformed donor-specific anti-HLA antibodies in kidney transplantation.

Salvadé I, Aubert V, Venetz JP, Golshayan D, Saouli AC, Matter M, Rotman S, Pantaleo G, Pascual M

Hum Immunol. 2016 Jun;77(6):483-9

Emergence of Acquired HIV-1 Drug Resistance Almost Stopped in Switzerland: A 15-Year Prospective Cohort Analysis.

Scherrer AU, von Wyl V, Yang WL, Kouyos RD, Böni J, Yerly S, Klimkait T, Aubert V, Cavassini M, Battegay M, Furrer H, Calmy A, Vernazza P, Bernasconi E, Günthard HF, Swiss HIV Cohort Study., Aubert V, Battegay M, Bernasconi E, Böni J, Braun DL, Bucher HC,

Clin Infect Dis. 2016 May 15;62(10):1310-1317

Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques.

Zurawski G, Zurawski S, Flamar AL, Richert L, Wagner R, Tomaras GD, Montefiori DC, Roederer M, Ferrari G, Lacabaratz C, Bonnabau H, Klucar P, Wang Z, Foulds KE, Kao SF, Yates NL, LaBranche C, Jacobs BL, Kibler K, Asbach B, Kliche A, Salazar A, Reed S, Sel

PLoS One. 2016;11(4):e0153484

The Swiss Multiple Sclerosis Cohort-Study (SMSC): A Prospective Swiss Wide Investigation of Key Phases in Disease Evolution and New Treatment Options.

Disanto G, Benkert P, Lorscheider J, Mueller S, Vehoff J, Zecca C, Ramseier S, Achtnichts L, Findling O, Nedeltchev K, Radue EW, Sprenger T, Stippich C, Derfuss T, Louvion JF, Kamm CP, Mattle HP, Lotter C, Du Pasquier R, Schluep M, Pot C, Lalive PH, Yaldi

PLoS One. 2016;11(3):e0152347

Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens.

Asbach B, Kliche A, Köstler J, Perdiguero B, Esteban M, Jacobs BL, Montefiori DC, LaBranche CC, Yates NL, Tomaras GD, Ferrari G, Foulds KE, Roederer M, Landucci G, Forthal DN, Seaman MS, Hawkins N, Self SG, Sato A, Gottardo R, Phogat S, Tartaglia J, Barne

J Virol. 2016 Apr;90(8):4133-4149

Advances of gene therapy for primary immunodeficiencies.

Candotti F

F1000Res. 2016;5

A case for preART-adjusted endpoints in HIV therapeutic vaccine trials.

Huang Y, Zhang L, Jolliffe D, Hovden AO, Ökvist M, Pantaleo G, Sommerfelt MA

Vaccine. 2016 Mar 4;34(10):1282-8

Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study.

De Santis O, Audran R, Pothin E, Warpelin-Decrausaz L, Vallotton L, Wuerzner G, Cochet C, Estoppey D, Steiner-Monard V, Lonchampt S, Thierry AC, Mayor C, Bailer RT, Mbaya OT, Zhou Y, Ploquin A, Sullivan NJ, Graham BS, Roman F, De Ryck I, Ballou WR, Kieny

Lancet Infect Dis. 2016 Mar;16(3):311-20

The VZV/IE63-specific T cell response prevents herpes zoster in fingolimod-treated patients.

Mathias A, Perriard G, Canales M, Vuilleumier F, Perrotta G, Schluep M, Du Pasquier R

Neurol Neuroimmunol Neuroinflamm. 2016 Apr;3(2):e209

A New Approach for Deep Gray Matter Analysis Using Partial-Volume Estimation.

Bonnier G, Kober T, Schluep M, Du Pasquier R, Krueger G, Meuli R, Granziera C, Roche A

PLoS One. 2016;11(2):e0148631

N-WASP is required for B-cell-mediated autoimmunity in Wiskott-Aldrich syndrome.

Volpi S, Santori E, Abernethy K, Mizui M, Dahlberg CI, Recher M, Capuder K, Csizmadia E, Ryan D, Mathew D, Tsokos GC, Snapper S, Westerberg LS, Thrasher AJ, Candotti F, Notarangelo LD

Blood. 2016 Jan 14;127(2):216-20

HIV-1 Transmission During Recent Infection and During Treatment Interruptions as Major Drivers of New Infections in the Swiss HIV Cohort Study.

Marzel A, Shilaih M, Yang WL, Böni J, Yerly S, Klimkait T, Aubert V, Braun DL, Calmy A, Furrer H, Cavassini M, Battegay M, Vernazza PL, Bernasconi E, Günthard HF, Kouyos RD, Swiss HIV Cohort Study., Aubert V, Battegay M, Bernasconi E, Böni J, Bucher HC, B

Clin Infect Dis. 2016 Jan 1;62(1):115-122

Prophylactic immunization of mice with phospholipase A2-loaded gas-filled microbubbles is protective against Th2-mediated honeybee venom allergy.

Bioley G, Lassus A, Terrettaz J, Tranquart F, Corthésy B

Clin Exp Allergy. 2016 Jan;46(1):153-62

Delivery of antigen to nasal-associated lymphoid tissue microfold cells through secretory IgA targeting local dendritic cells confers protective immunity.

Rochereau N, Pavot V, Verrier B, Jospin F, Ensinas A, Genin C, Corthésy B, Paul S

J Allergy Clin Immunol. 2016 Jan;137(1):214-222.e2

2015

Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency.

Komarow HD, Sokolic R, Hershfield MS, Kohn DB, Young M, Metcalfe DD, Candotti F

Orphanet J Rare Dis. 2015 Dec 18;10:159

In Vitro Reactivation of Replication-Competent and Infectious HIV-1 by Histone Deacetylase Inhibitors.

Banga R, Procopio FA, Cavassini M, Perreau M

J Virol. 2016 Feb 15;90(4):1858-71

Progressive multifocal leukoencephalopathy in common variable immunodeficiency: mitigated course under mirtazapine and mefloquine.

Kurmann R, Weisstanner C, Kardas P, Hirsch HH, Wiest R, Lämmle B, Furrer H, Du Pasquier R, Bassetti CL, Sturzenegger M, Krestel H

J Neurovirol. 2015 Dec;21(6):694-701

NBAS mutations cause a multisystem disorder involving bone, connective tissue, liver, immune system, and retina.

Segarra NG, Ballhausen D, Crawford H, Perreau M, Campos-Xavier B, van Spaendonck-Zwarts K, Vermeer C, Russo M, Zambelli PY, Stevenson B, Royer-Bertrand B, Rivolta C, Candotti F, Unger S, Munier FL, Superti-Furga A, Bonafé L

Am J Med Genet A. 2015 Dec;167A(12):2902-12

Safety of human immunisation with a live-attenuated Mycobacterium tuberculosis vaccine: a randomised, double-blind, controlled phase I trial.

Spertini F, Audran R, Chakour R, Karoui O, Steiner-Monard V, Thierry AC, Mayor CE, Rettby N, Jaton K, Vallotton L, Lazor-Blanchet C, Doce J, Puentes E, Marinova D, Aguilo N, Martin C

Lancet Respir Med. 2015 Dec;3(12):953-62

Relapse in herpes simplex virus encephalitis: It's not just about the virus.

Bale JF Jr, Du Pasquier R

Neurology. 2015 Nov 17;85(20):1730-1

Broad spectrum of autoantibodies in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia.

Crestani E, Volpi S, Candotti F, Giliani S, Notarangelo LD, Chu J, Aldave Becerra JC, Buchbinder D, Chou J, Geha RS, Kanariou M, King A, Mazza C, Moratto D, Sokolic R, Garabedian E, Porta F, Putti MC, Wakim RH, Tsitsikov E, Pai SY, Notarangelo LD

J Allergy Clin Immunol. 2015 Nov;136(5):1401-4.e1-3

Immune correlates of vaccine protection against HIV-1 acquisition.

Corey L, Gilbert PB, Tomaras GD, Haynes BF, Pantaleo G, Fauci AS

Sci Transl Med. 2015 Oct 21;7(310):310rv7

Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice.

Yokoyama T, Yoshizaki A, Simon KL, Kirby MR, Anderson SM, Candotti F

PLoS One. 2015;10(10):e0139729

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.

Pala F, Morbach H, Castiello MC, Schickel JN, Scaramuzza S, Chamberlain N, Cassani B, Glauzy S, Romberg N, Candotti F, Aiuti A, Bosticardo M, Villa A, Meffre E

J Clin Invest. 2015 Oct 1;125(10):3941-51

CSF lactate for accurate diagnosis of community-acquired bacterial meningitis.

Giulieri S, Chapuis-Taillard C, Jaton K, Cometta A, Chuard C, Hugli O, Du Pasquier R, Bille J, Meylan P, Manuel O, Marchetti O

Eur J Clin Microbiol Infect Dis. 2015 Oct;34(10):2049-55

Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome.

Kolhatkar NS, Brahmandam A, Thouvenel CD, Becker-Herman S, Jacobs HM, Schwartz MA, Allenspach EJ, Khim S, Panigrahi AK, Luning Prak ET, Thrasher AJ, Notarangelo LD, Candotti F, Torgerson TR, Sanz I, Rawlings DJ

J Exp Med. 2015 Sep 21;212(10):1663-77

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.

Søgaard OS, Graversen ME, Leth S, Olesen R, Brinkmann CR, Nissen SK, Kjaer AS, Schleimann MH, Denton PW, Hey-Cunningham WJ, Koelsch KK, Pantaleo G, Krogsgaard K, Sommerfelt M, Fromentin R, Chomont N, Rasmussen TA, Østergaard L, Tolstrup M

PLoS Pathog. 2015 Sep;11(9):e1005142

Schistosoma mansoni and HIV acquisition in fishing communities of Lake Victoria, Uganda: a nested case-control study.

Ssetaala A, Nakiyingi-Miiro J, Asiki G, Kyakuwa N, Mpendo J, Van Dam GJ, Corstjens PL, Pala P, Nielsen L, Bont J, Pantaleo G, Kiwanuka N, Kaleebu P, Kamali A, Elliott AM

Trop Med Int Health. 2015 Sep;20(9):1190-1195

A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-up.

Derfuss T, Curtin F, Guebelin C, Bridel C, Rasenack M, Matthey A, Du Pasquier R, Schluep M, Desmeules J, Lang AB, Perron H, Faucard R, Porchet H, Hartung HP, Kappos L, Lalive PH

J Neuroimmunol. 2015 Aug 15;285:68-70

Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman Primates.

García-Arriaza J, Perdiguero B, Heeney J, Seaman M, Montefiori DC, Labranche C, Yates NL, Shen X, Tomaras GD, Ferrari G, Foulds KE, McDermott A, Kao SF, Roederer M, Hawkins N, Self S, Yao J, Farrell P, Phogat S, Tartaglia J, Barnett SW, Burke B, Cristillo

J Virol. 2015 Aug;89(16):8525-39

Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.

Shen X, Duffy R, Howington R, Cope A, Sadagopal S, Park H, Pal R, Kwa S, Ding S, Yang OO, Fouda GG, Le Grand R, Bolton D, Esteban M, Phogat S, Roederer M, Amara RR, Picker LJ, Seder RA, McElrath MJ, Barnett S, Permar SR, Shattock R, DeVico AL, Felber BK,

J Virol. 2015 Aug;89(16):8643-50

Decreasing Proportion of Recent Infections among Newly Diagnosed HIV-1 Cases in Switzerland, 2008 to 2013 Based on Line-Immunoassay-Based Algorithms.

Schüpbach J, Niederhauser C, Yerly S, Regenass S, Gorgievski M, Aubert V, Ciardo D, Klimkait T, Dollenmaier G, Andreutti C, Martinetti G, Brandenberger M, Gebhardt MD

PLoS One. 2015;10(7):e0131828

Emerging single-cell technologies in immunology.

Herderschee J, Fenwick C, Pantaleo G, Roger T, Calandra T

J Leukoc Biol. 2015 Jul;98(1):23-32

Identification and visualization of multidimensional antigen-specific T-cell populations in polychromatic cytometry data.

Lin L, Frelinger J, Jiang W, Finak G, Seshadri C, Bart PA, Pantaleo G, McElrath J, DeRosa S, Gottardo R

Cytometry A. 2015 Jul;87(7):675-82

Assessing the Paradox Between Transmitted and Acquired HIV Type 1 Drug Resistance Mutations in the Swiss HIV Cohort Study From 1998 to 2012.

Yang WL, Kouyos R, Scherrer AU, Böni J, Shah C, Yerly S, Klimkait T, Aubert V, Furrer H, Battegay M, Cavassini M, Bernasconi E, Vernazza P, Held L, Ledergerber B, Günthard HF, Swiss HIV Cohort Study.

J Infect Dis. 2015 Jul 1;212(1):28-38

Capacity for science in sub-Saharan Africa.

Elliott A, Nerima B, Bagaya B, Kambugu A, Joloba M, Cose S, Pantaleo G, Yazdanbakhsh M, Mabey D, Dunne D, Moffett A, Rwakishaya EK, Kaleebu P, Mbidde EK

Lancet. 2015 Jun 20;385(9986):2435-7

Individualized iterative phenotyping for genome-wide analysis of loss-of-function mutations.

Johnston JJ, Lewis KL, Ng D, Singh LN, Wynter J, Brewer C, Brooks BP, Brownell I, Candotti F, Gonsalves SG, Hart SP, Kong HH, Rother KI, Sokolic R, Solomon BD, Zein WM, Cooper DN, Stenson PD, Mullikin JC, Biesecker LG

Am J Hum Genet. 2015 Jun 4;96(6):913-25

Increases in Condomless Sex in the Swiss HIV Cohort Study.

Kouyos RD, Hasse B, Calmy A, Cavassini M, Furrer H, Stöckle M, Vernazza PL, Bernasconi E, Weber R, Günthard HF, Swiss HIV Cohort Study., Aubert V, Battegay M, Bernasconi E, Böni J, Bucher HC, Burton-Jeangros C, Calmy A, Cavassini M, Dollenmaier G, Egger M

Open Forum Infect Dis. 2015 Apr;2(2):ofv077

Synthetic long peptide booster immunization in rhesus macaques primed with replication-competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1.

Mooij P, Koopman G, Drijfhout JW, Nieuwenhuis IG, Beenhakker N, Koestler J, Bogers WM, Wagner R, Esteban M, Pantaleo G, Heeney JL, Jacobs BL, Melief CJ

J Gen Virol. 2015 Jun;96(Pt 6):1478-83

Assessment of Immature Platelet Fraction in the Diagnosis of Wiskott-Aldrich Syndrome.

Sokolic R, Oden N, Candotti F

Front Pediatr. 2015;3:49

A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients.

Derfuss T, Curtin F, Guebelin C, Bridel C, Rasenack M, Matthey A, Du Pasquier R, Schluep M, Desmeules J, Lang AB, Perron H, Faucard R, Porchet H, Hartung HP, Kappos L, Lalive PH

Mult Scler. 2015 Jun;21(7):885-93

COMPASS identifies T-cell subsets correlated with clinical outcomes.

Lin L, Finak G, Ushey K, Seshadri C, Hawn TR, Frahm N, Scriba TJ, Mahomed H, Hanekom W, Bart PA, Pantaleo G, Tomaras GD, Rerks-Ngarm S, Kaewkungwal J, Nitayaphan S, Pitisuttithum P, Michael NL, Kim JH, Robb ML, O'Connell RJ, Karasavvas N, Gilbert P, C De

Nat Biotechnol. 2015 Jun;33(6):610-6

Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein Boost.

Hulot SL, Korber B, Giorgi EE, Vandergrift N, Saunders KO, Balachandran H, Mach LV, Lifton MA, Pantaleo G, Tartaglia J, Phogat S, Jacobs B, Kibler K, Perdiguero B, Gomez CE, Esteban M, Rosati M, Felber BK, Pavlakis GN, Parks R, Lloyd K, Sutherland L, Scea

J Virol. 2015 Jun;89(12):6462-80

Outcomes in two Japanese adenosine deaminase-deficiency patients treated by stem cell gene therapy with no cytoreductive conditioning.

Otsu M, Yamada M, Nakajima S, Kida M, Maeyama Y, Hatano N, Toita N, Takezaki S, Okura Y, Kobayashi R, Matsumoto Y, Tatsuzawa O, Tsuchida F, Kato S, Kitagawa M, Mineno J, Hershfield MS, Bali P, Candotti F, Onodera M, Kawamura N, Sakiyama Y, Ariga T

J Clin Immunol. 2015 May;35(4):384-98

Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins.

Delaloye J, Filali-Mouhim A, Cameron MJ, Haddad EK, Harari A, Goulet JP, Gomez CE, Perdiguero B, Esteban M, Pantaleo G, Roger T, Sékaly RP, Calandra T

J Virol. 2015 Apr;89(7):3819-32

Multicontrast connectometry: a new tool to assess cerebellum alterations in early relapsing-remitting multiple sclerosis.

Romascano D, Meskaldji DE, Bonnier G, Simioni S, Rotzinger D, Lin YC, Menegaz G, Roche A, Schluep M, Pasquier RD, Richiardi J, Van De Ville D, Daducci A, Sumpf T, Fraham J, Thiran JP, Krueger G, Granziera C

Hum Brain Mapp. 2015 Apr;36(4):1609-19

NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses.

Di Pilato M, Mejías-Pérez E, Zonca M, Perdiguero B, Gómez CE, Trakala M, Nieto J, Nájera JL, Sorzano CO, Combadière C, Pantaleo G, Planelles L, Esteban M

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1333-42

Eculizumab to treat antibody-mediated rejection in a 7-year-old kidney transplant recipient.

Chehade H, Rotman S, Matter M, Girardin E, Aubert V, Pascual M

Pediatrics. 2015 Feb;135(2):e551-5

Combined use of Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis.

Rozot V, Patrizia A, Vigano S, Mazza-Stalder J, Idrizi E, Day CL, Perreau M, Lazor-Blanchet C, Ohmiti K, Goletti D, Bart PA, Hanekom W, Scriba TJ, Nicod L, Pantaleo G, Harari A

Clin Infect Dis. 2015 Feb 1;60(3):432-7

Virological and immunological characterization of novel NYVAC-based HIV/AIDS vaccine candidates expressing clade C trimeric soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as virus-like particles.

Perdiguero B, Gómez CE, Cepeda V, Sánchez-Sampedro L, García-Arriaza J, Mejías-Pérez E, Jiménez V, Sánchez C, Sorzano CÓ, Oliveros JC, Delaloye J, Roger T, Calandra T, Asbach B, Wagner R, Kibler KV, Jacobs BL, Pantaleo G, Esteban M

J Virol. 2015 Jan 15;89(2):970-88

2014

HIV-specific humoral responses benefit from stronger prime in phase Ib clinical trial.

Bart PA, Huang Y, Karuna ST, Chappuis S, Gaillard J, Kochar N, Shen X, Allen MA, Ding S, Hural J, Liao HX, Haynes BF, Graham BS, Gilbert PB, McElrath MJ, Montefiori DC, Tomaras GD, Pantaleo G, Frahm N

J Clin Invest. 2014 Nov;124(11):4843-56

Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders.

Perreau M, Vigano S, Bellanger F, Pellaton C, Buss G, Comte D, Roger T, Lacabaratz C, Bart PA, Levy Y, Pantaleo G

J Exp Med. 2014 Sep 22;211(10):2033-45

A 3 years retrospective study of survival for zirconia-based single crowns fabricated from intraoral digital impressions.

Gherlone E, Mandelli F, Capparè P, Pantaleo G, Traini T, Ferrini F

J Dent. 2014 Sep;42(9):1151-5

The dysfunction of T follicular helper cells.

Cubas R, Perreau M

Curr Opin HIV AIDS. 2014 Sep;9(5):485-91

HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment.

Castro E, Zhao H, Cavassini M, Mullins JI, Pantaleo G, Bart PA

AIDS. 2014 Jul 31;28(12):1840-4

Safety and immunogenicity of the M72/AS01 candidate tuberculosis vaccine in HIV-infected adults on combination antiretroviral therapy: a phase I/II, randomized trial.

Thacher EG, Cavassini M, Audran R, Thierry AC, Bollaerts A, Cohen J, Demoitié MA, Ejigu D, Mettens P, Moris P, Ofori-Anyinam O, Spertini F

AIDS. 2014 Jul 31;28(12):1769-81

Safety and immunogenicity of immunotherapy with Bet v 1-derived contiguous overlapping peptides.

Spertini F, Perrin Y, Audran R, Pellaton C, Boudousquié C, Barbier N, Thierry AC, Charlon V, Reymond C

J Allergy Clin Immunol. 2014 Jul;134(1):239-240.e13

Clustering of HCV coinfections on HIV phylogeny indicates domestic and sexual transmission of HCV.

Kouyos RD, Rauch A, Böni J, Yerly S, Shah C, Aubert V, Klimkait T, Kovari H, Calmy A, Cavassini M, Battegay M, Vernazza PL, Bernasconi E, Ledergerber B, Günthard HF, Swiss HIV Cohort Study (SHCS).

Int J Epidemiol. 2014 Jun;43(3):887-96

Natalizumab treatment alters the expression of T-cell trafficking marker LFA-1 α-chain (CD11a) in MS patients.

Jilek S, Mathias A, Canales M, Lysandropoulos A, Pantaleo G, Schluep M, Du Pasquier RA

Mult Scler. 2014 Jun;20(7):837-42

Safety and efficacy of the peptide-based therapeutic vaccine for HIV-1, Vacc-4x: a phase 2 randomised, double-blind, placebo-controlled trial.

Pollard RB, Rockstroh JK, Pantaleo G, Asmuth DM, Peters B, Lazzarin A, Garcia F, Ellefsen K, Podzamczer D, van Lunzen J, Arastéh K, Schürmann D, Clotet B, Hardy WD, Mitsuyasu R, Moyle G, Plettenberg A, Fisher M, Fätkenheuer G, Fischl M, Taiwo B, Baksaas I

Lancet Infect Dis. 2014 Apr;14(4):291-300

Long-term follow-up of a randomized trial on 118 patients with polyarteritis nodosa or microscopic polyangiitis without poor-prognosis factors.

Samson M, Puéchal X, Devilliers H, Ribi C, Cohen P, Bienvenu B, Ruivard M, Terrier B, Pagnoux C, Mouthon L, Guillevin L, French Vasculitis Study Group (FVSG).

Autoimmun Rev. 2014 Feb;13(2):197-205

[News in neurology 2013].

Spatola M, Rossetti AO, Michel P, Kuntzer T, Benninger D, Nater B, Démonet JF, Schluep M, Du Pasquier RA, Vingerhoets F

Rev Med Suisse. 2014 Jan 15;10(412-413):78-81

Comparison of two oral probiotic preparations in a randomized crossover trial highlights a potentially beneficial effect of Lactobacillus paracasei NCC2461 in patients with allergic rhinitis.

Perrin Y, Nutten S, Audran R, Berger B, Bibiloni R, Wassenberg J, Barbier N, Aubert V, Moulin J, Singh A, Magliola C, Mercenier A, Spertini F

Clin Transl Allergy. 2014 Jan 6;4(1):1

Role of secretory IgA in the mucosal sensing of commensal bacteria.

Mathias A, Pais B, Favre L, Benyacoub J, Corthésy B

Gut Microbes. 2014;5(6):688-95

Treatment-naive individuals are the major source of transmitted HIV-1 drug resistance in men who have sex with men in the Swiss HIV Cohort Study.

Drescher SM, von Wyl V, Yang WL, Böni J, Yerly S, Shah C, Aubert V, Klimkait T, Taffé P, Furrer H, Battegay M, Ambrosioni J, Cavassini M, Bernasconi E, Vernazza PL, Ledergerber B, Günthard HF, Kouyos RD, Swiss HIV Cohort Study.

Clin Infect Dis. 2014 Jan;58(2):285-94

Bone and soft tissue non-Hodgkin lymphoma of the maxillofacial area: report of two cases, literature review and new therapeutic strategies.

Cortese A, Pantaleo G, Ferrara I, Vatrella A, Cozzolino I, Di Crescenzo V, Amato M

Int J Surg. 2014;12 Suppl 2:S23-S28

2013

Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than "Exhaustion" of Human CD8 T Cells.

Legat A, Speiser DE, Pircher H, Zehn D, Fuertes Marraco SA

Front Immunol. 2013;4:455

[Granulomatous lymphocytic interstitial lung disease in common variable immunodeficiency].

Bianchi MP, Letovanec I, Spertini F, Nicod LP, Lazor R

Rev Med Suisse. 2013 Nov 20;9(407):2175-80

Rotavirus specific plasma secretory immunoglobulin in children with acute gastroenteritis and children vaccinated with an attenuated human rotavirus vaccine.

Herrera D, Vásquez C, Corthésy B, Franco MA, Angel J

Hum Vaccin Immunother. 2013 Nov;9(11):2409-17

[Biomarkers in clinical immunology].

Pardon A, Aubert V, Bart PA

Rev Med Suisse. 2013 Oct 30;9(404):1982, 1984-6, 1988-91

Origin of minority drug-resistant HIV-1 variants in primary HIV-1 infection.

Metzner KJ, Scherrer AU, Preiswerk B, Joos B, von Wyl V, Leemann C, Rieder P, Braun D, Grube C, Kuster H, Böni J, Yerly S, Klimkait T, Aubert V, Furrer H, Battegay M, Vernazza PL, Cavassini M, Calmy A, Bernasconi E, Weber R, Günthard HF, Swiss HIV Cohort

J Infect Dis. 2013 Oct 1;208(7):1102-12

Assessing risks of multiple sclerosis therapies.

Parfenov V, Schluep M, Du Pasquier R

J Neurol Sci. 2013 Sep 15;332(1-2):59-65

Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma.

Lange CM, Bibert S, Dufour JF, Cellerai C, Cerny A, Heim MH, Kaiser L, Malinverni R, Müllhaupt B, Negro F, Semela D, Moradpour D, Kutalik Z, Bochud PY, Swiss Hepatitis C Cohort Study Group.

J Hepatol. 2013 Sep;59(3):504-9

Gene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vector.

Horino S, Uchiyama T, So T, Nagashima H, Sun SL, Sato M, Asao A, Haji Y, Sasahara Y, Candotti F, Tsuchiya S, Kure S, Sugamura K, Ishii N

PLoS One. 2013;8(8):e71594

Multi-faceted functions of secretory IgA at mucosal surfaces.

Corthésy B

Front Immunol. 2013;4:185

Thirty years of HIV: what have we learned?

Cooper DA, Pantaleo G

Curr Opin HIV AIDS. 2013 Jul;8(4):304-5

Immune response to HIV.

Perreau M, Levy Y, Pantaleo G

Curr Opin HIV AIDS. 2013 Jul;8(4):333-40

Molecular insights for optimizing T cell receptor specificity against cancer.

Hebeisen M, Oberle SG, Presotto D, Speiser DE, Zehn D, Rufer N

Front Immunol. 2013;4:154

IL-12-mediated STAT4 signaling and TCR signal strength cooperate in the induction of CD40L in human and mouse CD8+ T cells.

Stark R, Hartung A, Zehn D, Frentsch M, Thiel A

Eur J Immunol. 2013 Jun;43(6):1511-7

Novel birch pollen specific immunotherapy formulation based on contiguous overlapping peptides.

Pellaton C, Perrin Y, Boudousquié C, Barbier N, Wassenberg J, Corradin G, Thierry AC, Audran R, Reymond C, Spertini F

Clin Transl Allergy. 2013 Jun 1;3(1):17

Mycobacterium tuberculosis-specific CD8+ T cells are functionally and phenotypically different between latent infection and active disease.

Rozot V, Vigano S, Mazza-Stalder J, Idrizi E, Day CL, Perreau M, Lazor-Blanchet C, Petruccioli E, Hanekom W, Goletti D, Bart PA, Nicod L, Pantaleo G, Harari A

Eur J Immunol. 2013 Jun;43(6):1568-77

Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development.

Lange CM, Miki D, Ochi H, Nischalke HD, Bojunga J, Bibert S, Morikawa K, Gouttenoire J, Cerny A, Dufour JF, Gorgievski-Hrisoho M, Heim MH, Malinverni R, Müllhaupt B, Negro F, Semela D, Kutalik Z, Müller T, Spengler U, Berg T, Chayama K, Moradpour D, Bochu

PLoS One. 2013;8(5):e64053

An analysis of the benefit of using HEV genotype 3 antigens in detecting anti-HEV IgG in a European population.

Schnegg A, Bürgisser P, André C, Kenfak-Foguena A, Canellini G, Moradpour D, Abravanel F, Izopet J, Cavassini M, Darling KE

PLoS One. 2013;8(5):e62980

Vaccine and immunotherapeutic interventions.

Pantaleo G, Lévy Y

Curr Opin HIV AIDS. 2013 May;8(3):236-42

[Head inflammation].

Du Pasquier RA, Lalive PH

Rev Med Suisse. 2013 May 1;9(384):907

[New treatment options in multiple sclerosis and their complications].

Schluep M, Lalive PH, Du Pasquier RA

Rev Med Suisse. 2013 May 1;9(384):940-3

[Peripheral blood eosinophilia: diagnostic value and further assessment].

Chappuis S, Ribi C, Greub G, Spertini F

Rev Med Suisse. 2013 Apr 17;9(382):819-25

[The bureaucratic jungle of off-list and off-label patients].

Seebach JD, Spertini F

Rev Med Suisse. 2013 Apr 17;9(382):795-6

Role of secretory IgA in infection and maintenance of homeostasis.

Corthésy B

Autoimmun Rev. 2013 Apr;12(6):661-5

Lack of Mycobacterium tuberculosis-specific interleukin-17A-producing CD4+ T cells in active disease.

Perreau M, Rozot V, Welles HC, Belluti-Enders F, Vigano S, Maillard M, Dorta G, Mazza-Stalder J, Bart PA, Roger T, Calandra T, Nicod L, Harari A

Eur J Immunol. 2013 Apr;43(4):939-48

MOBP-specific cellular immune responses are weaker than MOG-specific cellular immune responses in patients with multiple sclerosis and healthy subjects.

Jilek S, Schluep M, Pantaleo G, Du Pasquier RA

Neurol Sci. 2013 Apr;34(4):539-43

The candidate tuberculosis vaccine Mtb72F/AS02 in PPD positive adults: a randomized controlled phase I/II study.

Spertini F, Audran R, Lurati F, Ofori-Anyinam O, Zysset F, Vandepapelière P, Moris P, Demoitié MA, Mettens P, Vinals C, Vastiau I, Jongert E, Cohen J, Ballou WR

Tuberculosis (Edinb). 2013 Mar;93(2):179-88

Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α-kinoid.

Lauwerys BR, Hachulla E, Spertini F, Lazaro E, Jorgensen C, Mariette X, Haelterman E, Grouard-Vogel G, Fanget B, Dhellin O, Vandepapelière P, Houssiau FA

Arthritis Rheum. 2013 Feb;65(2):447-56

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production.

Perreau M, Savoye AL, De Crignis E, Corpataux JM, Cubas R, Haddad EK, De Leval L, Graziosi C, Pantaleo G

J Exp Med. 2013 Jan 14;210(1):143-56

Marked increase of the astrocytic marker S100B in the cerebrospinal fluid of HIV-infected patients on LPV/r-monotherapy.

Du Pasquier RA, Jilek S, Kalubi M, Yerly S, Fux CA, Gutmann C, Cusini A, Günthard HF, Cavassini M, Vernazza PL, Swiss HIV Cohort Study.

AIDS. 2013 Jan 14;27(2):203-10

[Systemic mastocytosis--new therapeutic strategies].

Maniu CM, Ribi C, Spertini F

Rev Med Suisse. 2013 Jan 9;9(368):17-21

[Management of adverse events induced by TNFalpha blocking agents].

Chappuis S, Ribi C, Spertini F

Rev Med Suisse. 2013 Jan 9;9(368):12-6

[2012: news in neurology].

Alvarez V, Rossetti AO, Michel P, Kuntzer T, Nater B, Démonet JF, Schluep M, Du Pasquier R, Vingerhoets F

Rev Med Suisse. 2013 Jan 9;9(368):62-5

A light in the cognitive fog?

Cavassini M, Du Pasquier RA

Antivir Ther. 2013;18(2):149-51

The individualized genetic barrier predicts treatment response in a large cohort of HIV-1 infected patients.

Beerenwinkel N, Montazeri H, Schuhmacher H, Knupfer P, von Wyl V, Furrer H, Battegay M, Hirschel B, Cavassini M, Vernazza P, Bernasconi E, Yerly S, Böni J, Klimkait T, Cellerai C, Günthard HF, Swiss HIV Cohort Study.

PLoS Comput Biol. 2013;9(8):e1003203

Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells.

Viganò S, Bellutti Enders F, Miconnet I, Cellerai C, Savoye AL, Rozot V, Perreau M, Faouzi M, Ohmiti K, Cavassini M, Bart PA, Pantaleo G, Harari A

PLoS Pathog. 2013;9(7):e1003423

2012

Impairment of JCV-specific T-cell response by corticotherapy: effect on PML-IRIS management?

Antoniol C, Jilek S, Schluep M, Mercier N, Canales M, Le Goff G, Campiche C, Pantaleo G, Du Pasquier RA

Neurology. 2012 Dec 4;79(23):2258-64

The role of secretory immunoglobulin A in the natural sensing of commensal bacteria by mouse Peyer's patch dendritic cells.

Rol N, Favre L, Benyacoub J, Corthésy B

J Biol Chem. 2012 Nov 16;287(47):40074-82

FluxEXPLORER: a new high-speed laser Doppler imaging system for the assessment of burn injuries.

Erba P, Espinoza D, Koch N, Christen T, Serov A, Raffoul W

Skin Res Technol. 2012 Nov;18(4):456-61

NYVAC immunization induces polyfunctional HIV-specific T-cell responses in chronically-infected, ART-treated HIV patients.

Harari A, Rozot V, Cavassini M, Bellutti Enders F, Vigano S, Tapia G, Castro E, Burnet S, Lange J, Moog C, Garin D, Costagliola D, Autran B, Pantaleo G, Bart PA

Eur J Immunol. 2012 Nov;42(11):3038-48

T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology.

King CG, Koehli S, Hausmann B, Schmaler M, Zehn D, Palmer E

Immunity. 2012 Oct 19;37(4):709-20

Immune response to hepatitis B vaccination in HIV-positive adults with isolated antibodies to HBV core antigen.

Kaech C, Pache I, Bürgisser P, Elzi L, Darling KE, Cavassini M

J Infect. 2012 Aug;65(2):157-64

The number of Toll-like receptor 9-agonist motifs in the adenovirus genome correlates with induction of dendritic cell maturation by adenovirus immune complexes.

Perreau M, Welles HC, Pellaton C, Gjoksi B, Potin L, Martin R, Harari A, Bett A, Casimiro D, Gall J, Barouch DH, Kremer EJ, Pantaleo G

J Virol. 2012 Jun;86(11):6279-85

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities.

McNerney R, Maeurer M, Abubakar I, Marais B, McHugh TD, Ford N, Weyer K, Lawn S, Grobusch MP, Memish Z, Squire SB, Pantaleo G, Chakaya J, Casenghi M, Migliori GB, Mwaba P, Zijenah L, Hoelscher M, Cox H, Swaminathan S, Kim PS, Schito M, Harari A, Bates M,

J Infect Dis. 2012 May 15;205 Suppl 2:S147-58

Nonrandom distribution of cryptic repeating triplets of purines and pyrimidines (RNY)(n) in gp120 of HIV Type1.

De Crignis E, Guglietta S, Foley BT, Negroni M, Di Narzo AF, Waelti Da Costa V, Cavassini M, Bart PA, Pantaleo G, Graziosi C

AIDS Res Hum Retroviruses. 2012 May;28(5):493-504

HLA-B7-restricted EBV-specific CD8+ T cells are dysregulated in multiple sclerosis.

Jilek S, Schluep M, Harari A, Canales M, Lysandropoulos A, Zekeridou A, Pantaleo G, Du Pasquier RA

J Immunol. 2012 May 1;188(9):4671-80

Modulation of human memory T-cell function by different antigen-presenting cells.

Perreau M, Welles HC, Harari A, Calandra T, Roger T, Pantaleo G

Eur J Immunol. 2012 Mar;42(3):799-802

Positive and negative regulation of cellular immune responses in physiologic conditions and diseases.

Viganò S, Perreau M, Pantaleo G, Harari A

Clin Dev Immunol. 2012;2012:485781

Functional avidity: a measure to predict the efficacy of effector T cells?

Viganò S, Utzschneider DT, Perreau M, Pantaleo G, Zehn D, Harari A

Clin Dev Immunol. 2012;2012:153863

2011

[Immunological signatures: a new tool to diagnose active tuberculosis disease?].

Rozot V, Perreau M, Harari A, Pantaleo G

Med Sci (Paris). 2011 Oct;27(10):808-11

Large TCR diversity of virus-specific CD8 T cells provides the mechanistic basis for massive TCR renewal after antigen exposure.

Miconnet I, Marrau A, Farina A, Taffé P, Vigano S, Harari A, Pantaleo G

J Immunol. 2011 Jun 15;186(12):7039-49

HIV-1 vaccines and adaptive trial designs.

Corey L, Nabel GJ, Dieffenbach C, Gilbert P, Haynes BF, Johnston M, Kublin J, Lane HC, Pantaleo G, Picker LJ, Fauci AS

Sci Transl Med. 2011 Apr 20;3(79):79ps13

Early and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-term non-progressors.

Cellerai C, Harari A, Stauss H, Yerly S, Geretti AM, Carroll A, Yee T, Ainsworth J, Williams I, Sweeney J, Freedman A, Johnson M, Pantaleo G, Kinloch-de Loes S

PLoS One. 2011 Apr 5;6(4):e18164

Effect of Lactobacillus paracasei ST11 on a nasal provocation test with grass pollen in allergic rhinitis.

Wassenberg J, Nutten S, Audran R, Barbier N, Aubert V, Moulin J, Mercenier A, Spertini F

Clin Exp Allergy. 2011 Apr;41(4):565-73

Dominant TNF-α+ Mycobacterium tuberculosis-specific CD4+ T cell responses discriminate between latent infection and active disease.

Harari A, Rozot V, Bellutti Enders F, Perreau M, Stalder JM, Nicod LP, Cavassini M, Calandra T, Blanchet CL, Jaton K, Faouzi M, Day CL, Hanekom WA, Bart PA, Pantaleo G

Nat Med. 2011 Mar;17(3):372-6

2010

HIV-1 drug resistance transmission networks in southwest Switzerland.

Castro E, Khonkarly M, Ciuffreda D, Bürgisser P, Cavassini M, Yerly S, Pantaleo G, Bart PA

AIDS Res Hum Retroviruses. 2010 Nov;26(11):1233-8

Randomized double-blind controlled Phase I/IIa trial to assess the efficacy of malaria vaccine PfCS102 to protect against challenge with P. falciparum.

Genton B, D'Acremont V, Lurati-Ruiz F, Verhage D, Audran R, Hermsen C, Wolters L, Reymond C, Spertini F, Sauerwein R

Vaccine. 2010 Sep 14;28(40):6573-80

Poxvirus vector-based HIV vaccines.

Pantaleo G, Esteban M, Jacobs B, Tartaglia J

Curr Opin HIV AIDS. 2010 Sep;5(5):391-6

Cytokine mRNA profile of Epstein-Barr virus-stimulated highly differentiated T cells in multiple sclerosis: a pilot study.

Jaquiéry E, Jilek S, Schluep M, Le Goff G, Garcia M, Pantaleo G, Du Pasquier RA

J Neuroimmunol. 2010 Aug 25;225(1-2):167-70

Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells.

Krieg C, Létourneau S, Pantaleo G, Boyman O

Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11906-11

Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression.

Cellerai C, Perreau M, Rozot V, Bellutti Enders F, Pantaleo G, Harari A

J Virol. 2010 Apr;84(8):3868-78

Long sequence duplications, repeats, and palindromes in HIV-1 gp120: length variation in V4 as the product of misalignment mechanism.

Guglietta S, Pantaleo G, Graziosi C

Virology. 2010 Mar 30;399(1):167-175

Immune responses to JC virus in patients with multiple sclerosis treated with natalizumab: a cross-sectional and longitudinal study.

Jilek S, Jaquiéry E, Hirsch HH, Lysandropoulos A, Canales M, Guignard L, Schluep M, Pantaleo G, Du Pasquier RA

Lancet Neurol. 2010 Mar;9(3):264-72

Intrathecal immune responses to EBV in early MS.

Jaquiéry E, Jilek S, Schluep M, Meylan P, Lysandropoulos A, Pantaleo G, Du Pasquier RA

Eur J Immunol. 2010 Mar;40(3):878-87

IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25.

Létourneau S, van Leeuwen EM, Krieg C, Martin C, Pantaleo G, Sprent J, Surh CD, Boyman O

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2171-6

Hepatitis C virus infection after liver transplantation is associated with lower levels of activated CD4(+)CD25(+)CD45RO(+)IL-7ralpha(high) T cells.

Ciuffreda D, Codarri L, Buhler L, Vallotton L, Giostra E, Mentha G, Morel P, Pantaleo G, Pascual M

Liver Transpl. 2010 Jan;16(1):49-55

2009

Are all donor-specific antibodies detected by solid-phase assay before transplantation clinically relevant ?

Aubert V., Venetz J.-P., Pantaleo G. and Pascual M.

Transplantation. 2009 Jun 27;87(12):1897-8

Associations of serum EBV DNA and gammopathy with post-transplant lymphoproliferative disease.

Rosselet A., Vu D.H., Meylan P., Chaubert A.S., Schapira M., Pascual M., Aubert V., Tissot J.D. and Duchosal M.A.

Clin Transplant. 2009 Jan-Feb;23(1):74-82

Allergie rhinoconjunctivitis and immunotherapy: an uptodate.

Leimgruber A. and Spertini F.

Rev Med Suisse. 2009 Jan 14;5(186):88-93

IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets.

Létourneau S., Krieg C., Pantaleo G. and Boyman O.

J Allergy Clin Immunol. 2009 Apr;123(4):758-62

Comparison of human and rhesus macaque T-cell responses elicited by boosting with NYVAC encoding HIV-1 clade C immunogens.

Mooij P., Balla-Jhagjhoorsingh S.S., Beenhakker N., van Haaften P., Baak I., Nieuwenhuis I.G., Heidari S., Wolf H., Frachette M.J., Bieler K., Sheppard N., Harari A., Bart P.-A., Liljeström P., Wagner R., Pantaleo G. and Heeney JL.

J Virol. 2009 Jun;83(11):5881-9

Encephalitis, HSV-2 in the cerebrospinal fluid and anti-RI (ANNA-2) antibodies: an infectious or a paraneoplastic syndrome ?

Novy J., Carota A., Eggiman D., Pusztaszeri M., Rossetti A.O. and Du Pasquier R.A.

BMJ Case Reports. August 11, 2009.

Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated Plasmodium falciparum protein PFF0165c.

Olugbile S., Kulangara C., Bang G., Bertholet S., Suzarte E., Villard V., Frank G., Audran R., Razaname A., Nebie I., Awobusuyi O., Spertini F., Kajava A.V., Felger I., Druilhe P. and Corradin G.

Infect Immun. 2009 Dec;77(12):5701-9

Allergen-specific antibody and cytokine responses, mast cell reactivity and intestinal permeability upon oral challenge of sensitized and tolerized mice.

Perrier C., Thierry A.C., Mercenier A. and Corthésy B.

Clin Exp Allergy. 2010 Jan;40(1):153-62

Use of autoantibodies in clinical practice.

Petitpierre S., Aubert V., Leimgruber A., Spertini F. and Bart P.-A.

Rev Med Suisse. 2009 Apr 15;5(199):823-31

Prevalence of etravirine mutations and impact on response to treatment in routine clinical care: the Swiss HIV Cohort Study (SHCS).

Scherrer A.U., Hasse B., von Wyl V., Yerly S., Böni J., Bürgisser P., Klimkait T., Bucher H.C., Ledergerber B. and Günthard H.F.

HIV Med. 2009 Nov;10(10):647-56

Autoantibodies in neurological diseases: clinical implications

Lalive P.H., Chofflon M., Du Pasquier R.A. and Burkhard P.R.

Rev Med Suisse. 2009 Apr 29;5(201):942-4, 946-8, 950

Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells.

Schmutz S., Bosco N., Chappaz S., Boyman O., Acha-Orbea H., Ceredig R., Rolink A.G. and Finke D.

J Immunol. 2009 Aug 15;183(4):2217-21

Progressive decline of decision-making performances during multiple sclerosis.

Simioni S., Ruffieux C., Kleeberg J., Bruggimann L., du Pasquier R.A., Annoni J.M. and Schluep M.

J Int Neuropsychol Soc. 2009 Mar;15(2):291-5

Allergology and clinical immunology: a crossover discipline.

Spertini F. and Seebach J.

Rev Med Suisse. 2009 Apr 15;5(199):803-4

Predictors of asthma control in everyday clinical practice in Switzerland.

Taegtmeyer A.B., Steurer-Stey C., Price D.B., Wildhaber J.H., Spertini F. and Leuppi JD.

Curr Med Res Opin. 2009 Oct;25(10):2549-55

Allergic rhinitis in patients with asthma: the Swiss LARA (Link Allergic Rhinitis in Asthma) survey.

Taegtmeyer A.B., Steurer-Stey C., Spertini F., Bircher A., Helbling A., Miedinger D., Schafroth S., Scherer K. and Leuppi J.D.

Curr Med Res Opin. 2009 May;25(5):1073-80

Conditioned polarized Caco-2 cell monolayers allow to discriminate for the ability of gut-derived microorganisms to modulate permeability and antigen-induced basophil degranulation.

Thierry A.C., Bernasconi E., Mercenier A. and Corthésy B.

Clin Exp Allergy. 2009 Apr;39(4):527-36

In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression.

Webster K.E., Walters S., Kohler R.E., Mrkvan T., Boyman O., Surh C.D., Grey S.T. and Sprent J.

J Exp Med. 2009 Apr 13;206(4):751-60

Pyoderma gangrenosum: a rare pathology or an omitted diagnosis ?

Lê Huu S., Spertini F., Roggero P., Egloff D.V. and Raffoul W.

Ann Chir Plast Esthet. 2009 Feb;54(1):82-7

The role of chemokines in cancer immune surveillance by the adaptive immune system.

Krieg C. and Boyman O.

Semin Cancer Biol. 2009 Apr;19(2):76-83

Low levels of human leukocyte antigen donor-specific antibodies detected by solid phase assay before transplantation are frequently clinically irrelevant.

Aubert V., Venetz J.-P., Pantaleo G. and Pascual M.

Hum Immunol. 2009 Aug;70(8):580-3

Secretory immunoglobulin A: well beyond immune exclusion at mucosal surfaces.

Corthésy B.

Immunopharmacol Immunotoxicol. 2009 Jun;31(2):174-9

The synthetic Plasmodium falciparum circumsporozoite peptide PfCS102 as a malaria vaccine candidate: a randomized controlled phase I trial.

Audran R., Lurati-Ruiz F., Genton B., Blythman H.E., Ofori-Anyinam O., Reymond C., Corradin G. and Spertini F.

PLoS One. 2009 Oct 2;4(10):e7304

The polymorphic nature of HIV type 1 env V4 affects the patterns of potential N-glycosylation sites in proviral DNA at the intrahost level.

Bélair M., Dovat M., Foley B., Mayerat C., Pantaleo G. and Graziosi C.

AIDS Res Hum Retroviruses. 2009 Feb;25(2):199-206

CD4+CD25+ T cell depletion impairs tolerance induction in a murine model of asthma.

Boudousquié C., Pellaton C., Barbier N. and Spertini F.

Clin Exp Allergy. 2009 Sep;39(9):1415-26

Secretory IgA-mediated neutralization of Shigella flexneri prevents intestinal tissue destruction by down-regulating inflammatory circuits.

Boullier S., Tanguy M., Kadaoui K.A., Caubet C., Sansonetti P., Corthésy B. and Phalipon A.

J Immunol. 2009 Nov 1;183(9):5879-85

Homeostatic proliferation and survival of naïve and memory T cells.

Boyman O., Létourneau S., Krieg C. and Sprent J.

Eur J Immunol. 2009 Aug;39(8):2088-94

Antigen exposure regulates the balance between proliferating and cytotoxic subsets of virus-specific CD8 T-cells

Cellerai C., Perreau M., Rozot V., Bellutti Enders F., Bart P.-A., Pantaleo G. and Harari A.

Retrovirology 2009, 6(Suppl 3):261.

Prolonged seroconversion in an elite controller of HIV-1 infection.

Clerc O., Cavassini M., Böni J., Schüpbach J. and Bürgisser P.

J Clin Virol. 2009 Dec;46(4):371-3

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.

Delaloye J., Roger T., Steiner-Tardivel Q.G., Le Roy D., Knaup Reymond M., Akira S., Petrilli V., Gomez C.E., Perdiguero B., Tschopp J., Pantaleo G., Esteban M. and Calandra T.

PLoS Pathog. 2009 Jun;5(6):e1000480

JC virus-specific immune responses in human immunodeficiency virus type 1 patients with progressive multifocal leukoencephalopathy.

Khanna N., Wolbers M., Mueller N.J., Garzoni C., Du Pasquier R.A., Fux C.A., Vernazza P., Bernasconi E., Viscidi R., Battegay M. and Hirsch H.H.; Swiss HIV Cohort Study.

J Virol. 2009 May;83(9):4404-11

Distinct profiles of cytotoxic granules in memory CD8 T-cells correlate with function, differentiation stage and antigen exposure.

Harari A., Bellutti Enders F., Cellerai C., Bart P.-A. and Pantaleo G.

J Virol. 2009 Apr;83(7):2862-71

Functional analysis of monocyte MHC class II compartments.

Bunbury A., Potolicchio I., Maitra R. and Santambrogio L.

FASEB J. 2009 Jan;23(1):164-71

Therapeutic strategies in idiopatic inflammatory myopathies.

Chakour R., Leimgruber A., Bart P.-A. and Spertini F.

Rev Med Suisse. 2009 Apr 15;5(199):812-8

Surveillance of HIV-1 drug resistance among naive patients from Venezuela.

Castillo J., Comegna M., Quijada W., Jauvin V., Pinson P., Masquelier B., Fleury H. and Castro E.

AIDS Res Hum Retroviruses. 2009 Dec;25(12):1329-33

Mastocytosis: when should it be considered ?

Comte-Perret S., Bart P.-A., Spertini F. and Leimgruber A.

Rev Med Suisse. 2009 Apr 15;5(199):837-42

New spectrum of HIV-associated cognitive disorders in the HAART era.

Du Pasquier R., Cavassini M., Simioni S., Annoni J.M., Giacobini E. and Hirschel B.

Rev Med Suisse. 2009 Apr 29;5(201):955-6, 958-61

Increased EBV reactivation in the cerebrospinal fluid of patients with early multiple sclerosis.

Jaquiéry E. , Jilek S. , Schluep M. , Meylan P. , Lysandropoulos A. , Pantaleo G. and Du Pasquier R.A.

J. Neurovirol. 2009, 15:38.

Viral- and myelin-specific cellular immune response in patients treated with natalizumab: a cross-sectional and a longitudinal prospective study.

Jilek Terrasse S. , Lysandropoulos A. , Jaquiéry E. , Canales M. , Guignard L. , Campiche C. , Schluep M. , Pantaleo G. and Du Pasquier R.A.

J. Neurovirol. 2009, 15 (Suppl. 1):39-40.

Preclinical evaluation of the immunogenicity of C-type HIV-1-based DNA and NYVAC vaccines in the Balb/C mouse model.

Wild J., Bieler K., Köstler J., Frachette M.J., Jeffs S., Vieira S., Esteban M., Liljeström P., Pantaleo G., Wolf H. and Wagner R.

Viral Immunol. 2009 Oct;22(5):309-19

2008

Improved diagnoses of autoimmune hepatitis using an anti-actin ELISA.

Aubert V., Graf Pisler I. and Spertini F.

J Clin Lab Anal. 2008;22(5):340-5

HIV-1-specific immune response.

Harari A. and Pantaleo G.

Adv Pharmacol. 2008;56:75-92

HIV-1 coreceptor usage and CXCR4-specific viral load predict clinical disease progression during combination antiretroviral therapy.

Weiser B., Philpott S., Klimkait T., Burger H., Kitchen C., Bürgisser P., Gorgievski M., Perrin L., Piffaretti J.C. and Ledergerber B.; Swiss HIV Cohort Study.

AIDS. 2008 Feb 19;22(4):469-79

The eternal gap...

Villard J. and Spertini F.

Rev Med Suisse. 2008 Apr 23;4(154):1011

Severe anaphylactic shock to Patent Blue V with cardiac arrest during breast carcinoma surgery with lymphatic mapping.

Thierrin L., Steiger D., Zuber J.-P., Spertini F., Brunisholz Y. and Delaloye J.-F.

Eur J Obstet Gynecol Reprod Biol. 2008 Sep;140(1):140-1

T cell homeostasis.

Sprent J., Cho J.H., Boyman O. and Surh C.D.

Immunol Cell Biol. 2008 May-Jun;86(4):312-9

Heerfordt syndrome with unilateral facial nerve palsy: a rare presentation of sarcoidosis.

Petropoulos I.K., Zuber J.-P. and Guex-Crosier Y.

Klin Monbl Augenheilkd. 2008 May;225(5):453-6

The multiple etiologies of angioedema

Petitpierre S., Bart P.-A., Spertini F. and Leimgruber A.

Rev Med Suisse. 2008 Apr 23;4(154):1030-4, 1036-8

Activation of a dendritic cell–T cell axis by Ad5 immune complexes creates an improved environment for replication of HIV in T cells.

Perreau M., Pantaleo G. and Kremer E.J.

J Exp Med. 2008 Nov 24;205(12):2717-25

HIV-1 T-cell vaccines: evaluating the next step.

Pantaleo G.

Lancet Infect Dis. 2008 Feb;8(2):82-3

Multicenter study of a new fully automated HBsAg screening assay with enhanced sensitivity for the detection of HBV mutants.

Muhlbacher A., Weber B., Burgisser P., Eiras A., Cabrera J., Louisirirotchanakul S., Tiller F.W., Kim H.S., Helden J.V., Bossi V. and Echevarria J.M.

Med Microbiol Immunol. 2008 Mar;197(1):55-64

A soluble hexameric form of CD40 ligand activates human dendritic cells and augments memory T cell response.

Miconnet I. and Pantaleo G.

Vaccine. 2008 Jul 29;26(32):4006-14

EV02: A Phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C alone.

McCormack S., Stöhr W., Barber T., Bart P.-A., Harari A., Moog C., Ciuffreda D., Cellerai C., Cowen M., Gamboni R., Burnet S., Legg K., Brodnicki E., Wolf H., Wagner R., Heeney J., Frachette M.J., Tartaglia J., Babiker A., Pantaleo G. and Weber J.

Vaccine. 2008 Jun 13;26(25):3162-74

Allergic reactions to nonsteroidal anti-inflammatory drugs.

Leimgruber A.

Rev Med Suisse. 2008 Jan 16;4(140):100-3

Inaugural description of Cogan syndrome in an HIV-infected person.

Kleeberg J., Maire R., Chave J.-P., Pournaras J.-A., Guex-Crosier Y. and Du Pasquier R.A.

J Neurol. 2008 Sep;255(9):1427-8

Strong EBV-specific CD8+ T cell response in patients with early multiple sclerosis.

Jilek S., Schluep M., Meylan P., Vingerhoets F., Guignard L., Monney A., Kleeberg J., Le Goff G., Pantaleo G. and Du Pasquier R.A.

Brain. 2008 Jul;131(Pt 7):1712-21

Insight in the factors associated with the presence of protective antiviral T-cell response.

Harari A., Bellutti Enders F., Garcia M. and Pantaleo G.

Cytometry B. Clin. Cytom. 2008, 1:47.

Rare food allergies.

Bandelier C., Leimgruber A., Wassenberg J., Bart P.-A. and Spertini F.

Rev Med Suisse. 2008 Apr 23;4(154):1024-6, 1028-9

Neuropsychiatry.

Burkhard P.R., Vingerhoets F.J., Landis T. and Du Pasquier R.A.

Rev Med Suisse. 2008 May 7;4(156):1131-2

When should consider antiphospholipid syndrome ?

Bart P.-A.

Rev Med Suisse. 2008 Jan 16;4(140):97-9

EV01: A phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium.

Bart P.-A., Goodall R., Barber T., Harari A., Guimaraes-Walker A., Khonkarly M., Sheppard N.C., Bangala Y., Frachette M.J., Wagner R., Liljeström P., Kraehenbuhl J.-P., Girard M., Goudsmit J., Esteban M., Heeney J., Sattentau Q., McCormack S., Babiker A.,

Vaccine. 2008 Jun 13;26(25):3153-61

Severe occlusive vasculitis as a complication of cat scratch disease1.

Berguiga M., Abouzeid H., Bart P.-A. and Guex-Crosier Y.

Klin Monbl Augenheilkd. 2008 May;225(5):486-7

Phenotype and function of protective T cell immune rsponses in HIV.

Betts M.R. and Harari A.

Curr Opin HIV AIDS. 2008 May;3(3):349-55

IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T Cell expansion without lymphopenia.

Boyman O., Ramsey C., Kim D.M., Sprent J. and Surh C.D.

J Immunol. 2008 Jun 1;180(11):7265-75

c-Cbl expression levels regulate the functional responses of human central and effector memory CD4 T cells.

Brembilla N.C., Weber J., Rimoldi D., Pradervand S., Schutz F., Pantaleo G., Ruegg C., Quadroni M., Harshman K. and Doucey M.-A.

Blood. 2008 Aug 1;112(3):652-60

Restoration of anti-tetanus toxoid responses in patients initiating highly active antiretroviral therapy with or without a boost immunization: an INITIO substudy.

Burton C.T., Goodall R.L., Samri A., Autran B., Kelleher A.D., Poli G., Pantaleo G., Gotch F.M., Imami N.; INITIO Trial International Co-ordinating Committee.

Clin Exp Immunol. 2008 May;152(2):252-7

An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses.

Harari A., Bart P.-A., Stöhr W., Tapia G., Garcia M., Medjitna-Rais E., Burnet S., Cellerai C., Erlwein O., Barber T., Moog C., Liljestrom P., Wagner R., Wolf H., Kraehenbuhl J.-P., Esteban M., Heeney J., Frachette M.J., Tartaglia J., McCormack S., Babike

J Exp Med. 2008 Jan 21;205(1):63-77

Independent evolution of hypervariable regions of HIV-1 gp120: V4 as a swarm of N-Linked glycosylation variants.

Castro E., Bélair M., Rizzardi G.P., Bart P.-A., Pantaleo G. and Graziosi C.

AIDS Res Hum Retroviruses. 2008 Jan;24(1):106-13

Neurology.

Cereda C. and Du Pasquier R.

Rev Med Suisse. 2008 Jan 9;4(139):49-50, 52-6

Polyfunctional HCV-specific T-cell responses are associated with effective control of HCV replication.

Ciuffreda D., Comte D., Cavassini M., Giostra E., Bühler L., Perruchoud M., Heim M.H., Battegay M., Genné D., Mulhaupt B., Malinverni R., Oneta C., Bernasconi E., Monnat M., Cerny A., Chuard C., Borovicka J., Mentha G., Pascual M., Gonvers J.J., Pantaleo

Eur J Immunol. 2008 Oct;38(10):2665-77

Aerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenic.

Corbett M., Bogers W.M., Heeney J.L., Gerber S., Genin C., Didierlaurent A., Oostermeijer H., Dubbes R., Braskamp G., Lerondel S., Gomez C.E., Esteban M., Wagner R., Kondova I., Mooij P., Balla-Jhagjhoorsingh S., Beenhakker N., Koopman G., van der Burg S.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2046-51

Effect of antiretroviral therapy on apoptosis markers and morphology in peripheral lymph nodes of HIV-infected Individuals.

Ehrhard S., Wernli M., Kaufmann G., Pantaleo G., Rizzardi G.P., Gudat F., Erb P. and Battegay M.

Infection. 2008 Mar;36(2):120-9

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses.

Gaucher D., Therrien R., Kettaf N., Angermann B.R., Boucher G., Filali-Mouhim A., Moser J.M., Mehta R.S., Drake III D.R., Castro E., Akondy R., Rinfret A., Yassine-Diab B., Said E.A., Chouikh Y., Cameron M.J., Clum R., Kelvin D., Somogyi R., Greller L.D.,

J Exp Med. 2008 Dec 22;205(13):3119-31

Behçet's disease: from hippocrates to TNF-alpha-blockers.

Zuber J.-P., Bart P.-A., Leimgruber A. and Spertini F.

Rev Med Suisse. 2008 Apr 23;4(154):1045-8, 1050-4

2007

Functional patterns of HIV-1-specific CD4 T-cell responses in children are influenced by the extent of virus suppression and exposure.

Correa R., Harari A., Vallelian F., Resino S., Munoz-Fernandez M.A. and Pantaleo G.

AIDS. 2007 Jan 2;21(1):23-30

New trends in asthma therapy: is there a place for biologicals in 2007 ?

Bart P.-A.

Rev Med Suisse. 2007 Jan 17;3(94):103-6

Neuromyelitis optica following CMV primo-infection.

Tran C., Du Pasquier R.A., Cavassini M., Guex-Crosier Y., Meuli R., Ciuffreda D. and Waeber G.

J Intern Med. 2007 May;261(5):500-3

Modern nutrition and development of new allergies.

Wassenberg J., Ciuffreda D., Bart P.-A., Leimgruber A. and Spertini F.

Rev Med Suisse. 2007 Apr 25;3(108):1032-4, 1036-7

Lupine-induced anaphylaxis in a child without known food allergy.

Wassenberg J. and Hofer M.

Ann Allergy Asthma Immunol. 2007 Jun;98(6):589-90

Emergence of HIV-1 drug resistance in previously untreated patients initiating combination antiretroviral treatment: a comparison of different regimen types.

Von Wyl V., Yerly S., Boni J., Burgisser P., Klimkait T., Battegay M., Furrer H., Telenti A., Hirschel B., Vernazza P.L., Bernasconi E., Rickenbach M., Perrin L., Ledergerber B. and Gunthard H.F.; for the Swiss HIV Cohort Study.

Arch Intern Med. 2007 Sep 10;167(16):1782-90

Chimeric immune receptors (CIRs) specific to JC virus for immunotherapy in progressive multifocal leukoencephalopathy (PML).

Yang W., Beaudoin E.L., Lu L., Du Pasquier R.A., Kuroda M.J., Willemsen R.A., Koralnik I.J. and Junghans R.P.

Int Immunol. 2007 Sep;19(9):1083-93

Transmission of HIV-1 drug resistance in Switzerland: a 10-year molecular epidemiology survey.

Yerly S., von Wyl V., Ledergerber B., Böni J., Schüpbach J., Bürgisser P., Klimkait T., Rickenbach M., Kaiser L., Günthard H.F. and Perrin L.; Swiss HIV Cohort Study.

AIDS. 2007 Oct 18;21(16):2223-9

Sequence analysis of the novel HLA-B35 (B*3576) allele in an African individual.

Aubert V., Mayerat C., Lopez N. and Pantaleo G.

Tissue Antigens. 2007 Nov;70(5):439-41

Ex vivo monitoring of antigen specific CD4+ T cells after recall immunization with Tetanus toxoid.

Barbey C., Pradervand E., Barbier N. and Spertini F.

Clin Vaccine Immunol. 2007 Sep;14(9):1108-16

Solution structure of human secretory component and implications for biological function.

Bonner A., Perrier C., Corthésy B. and Perkins S.J.

J Biol Chem. 2007 Jun 8;282(23):16969-80

Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells.

Shi L., Qiu D., Zhao G., Corthésy B., Lees-Miller S., Reeves W.H. and Kao P.N.

Nucleic Acids Res. 2007;35(7):2302-10

Neurology.

Botez S., Carota A., Dunand M., Du Pasquier R., Kuntzer T., Michel P., Morier J., Schluep M. and Rossetti A.O.

Rev Med Suisse. 2007 Jan 10;3(93):39-47

HIV type 1 drug resistance among naive patients from Venezuela.

Bouchard M., Masquelier B., Moreno M., Deibis L., de Pérez G., Fleury H. and Castro E.

AIDS Res Hum Retroviruses. 2007 Mar;23(3):482-5

The pathogenic role of tissue-resident immune cells in psoriasis.

Boyman O., Conrad C., Tonel G., Gilliet M. and Nestle F.O.

Trends Immunol. 2007 Feb;28(2):51-7

Cytokines and T-cell homeostasis.

Boyman O., Purton J.F., Surh C.D. and Sprent J.

Curr Opin Immunol. 2007 Jun;19(3):320-6

Severe interference between retinal angiography and automated four-color flow cytometry analysis of blood mononuclear cells.

Burgisser P., Vaudaux J. and Bart P.-A.

Cytometry A. 2007 Aug;71(8):632-6

Functional and phenotypic characterization of tetanus toxoid-specific human CD4(+) T cells following re-immunization.

Cellerai C., Harari A., Vallelian F., Boyman O. and Pantaleo G.

Eur J Immunol. 2007 Apr;37(4):1129-38

An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.

Cho J.H., Boyman O., Kim H.O., Hahm B., Rubinstein M.P., Ramsey C., Kim D.M., Surh C.D. and Sprent J.

J Exp Med. 2007 Aug 6;204(8):1787-801

Effects of immunosuppressive drugs on HIV infection: implications for solid-organ transplantation.

Ciuffreda D., Pantaleo G. and Pascual M.

Transpl Int. 2007 Aug;20(8):649-58

Expansion and tissue infiltration of an allospecific CD4+CD25+CD45RO+IL-7R{alpha}high cell population in solid organ transplant recipients.

Codarri L., Vallotton L., Ciuffreda D., Venetz J.P., Garcia M., Hadaya K., Buhler L., Rotman S., Pascual M. and Pantaleo G.

J Exp Med. 2007 Jul 9;204(7):1533-41

New concepts for the therapy of systemic lupus erythematosus.

Spertini F.

Rev Med Suisse. 2007 Jan 17;3(94):98-102

Assessment of recent HIV-1 infection by a line immunoassay for HIV-1/2 confirmation.

Schüpbach J., Gebhardt M.D., Tomasik Z., Niederhauser C., Yerly S., Bürgisser P., Matter L., Gorgievski M., Dubs R., Schultze D., Steffen I., Andreutti C., Martinetti G., Güntert B., Staub R., Daneel S. and Vernazza P.

PLoS Med. 2007 Dec;4(12):e343

Roundtrip ticket for secretory IgA: Role in mucosal homeostasis ?

Corthésy B.

J Immunol. 2007 Jan 1;178(1):27-32

CSF enrichment of highly differentiated CD8+ T cells in early multiple sclerosis.

Jilek S., Schluep M., Rosseti A.O., Guignard L., Le Goff G., Pantaleo G. and Du Pasquier R.A.

Clin Immunol. 2007 Apr;123(1):105-13

Cross-talk between probiotic bacteria and the host immune system.

Corthésy B., Gaskins H.R. and Mercenier A.

J Nutr. 2007 Mar;137(3 Suppl 2):781S-90S

Anaphylactic reaction to methylprednisolone in multiple sclerosis: a practical approach to alternative corticosteroids.

Deruaz C.A., Spertini F., Souza Lima F., Du Pasquier R.A. and Schluep M.

Mult Scler. 2007 May;13(4):559-60

Limbic encephalitis: another example of molecular mimicry ?

Du Pasquier R.

Eur Neurol. 2007;57(4):191-2

Impact of the molecular form of immunoglobulin A on functional activity in defense against Streptococcus pneumoniae.

Fasching C.E., Grossman T., Corthésy B., Plaut A.G., Weiser J.N. and Janoff E.N.

Infect Immun. 2007 Apr;75(4):1801-10

The trap: professional exposure to human immunodeficiency virus antibody negative blood with high viral load.

Giulieri S., Schiffer V., Yerly S., Bürgisser P., Hirschel B. and Cavassini M.

Arch Intern Med. 2007 Dec 10;167(22):2524-6

Generation and immunogenicity of novel HIV/AIDS vaccine candidates targeting HIV-1 Env/Gag-Pol-Nef antigens of clade C.

Gomez C.E., Najera J.L., Jimenez V., Bieler K., Wild J., Kostic L., Heidari S., Chen M., Frachette M.J., Pantaleo G., Wolf H., Liljestrom P., Wagner R. and Esteban M.

Vaccine. 2007 Mar 1;25(11):1969-92

Head-to-head comparison on the immunogenicity of two HIV/AIDS vaccine candidates based on the attenuated poxvirus strains MVA and NYVAC co-expressing in a single locus the HIV-1BX08 gp120 and HIV-1(IIIB) Gag-Pol-Nef proteins of clade B.

Gomez C.E., Najera J.L., Jimenez E.P., Jimenez V., Wagner R., Graf M., Frachette M.J., Liljestrom P., Pantaleo G. and Esteban M.

Vaccine. 2007 Apr 12;25(15):2863-85

Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype.

Harari A., Cellerai C., Bellutti Enders F., Köstler J., Codarri L., Tapia G., Boyman O., Castro E., Gaudieri S., James I., John M., Wagner R., Mallal S. and Pantaleo G.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16233-8

Severe post-EBV encephalopathy associated with myelin oligodendrocyte glycoprotein-specific immune response.

Jilek S., Kuhle J., Meylan P., Reichhart M.D., Pantaleo G. and Du Pasquier R.A.

J Neuroimmunol. 2007 Dec;192(1-2):192-7

Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment.

Kadaoui K.A. and Corthésy B.

J Immunol. 2007 Dec 1;179(11):7751-7

Three-year immune reconstitution in PI-sparing and PI-containing antiretroviral regimens in advanced HIV-1 disease.

Samri A., Goodall R., Burton C., Imami N., Pantaleo G., Kelleher A., Poli G., Gotch F. and Autran B.

Antivir Ther. 2007;12(4):553-8

B and T lymphocyte attenuator regulates CD8+ T cell-intrinsic homeostasis and memory cell generation.

Krieg C., Boyman O., Fu Y.X. and Kaye J.

Nat Immunol. 2007 Feb;8(2):162-71

Treatment of asthma and rhinits during pregnancy and breast feeding.

Leimgruber A.

Rev Med Suisse. 2007 Apr 25;3(108):1044-6, 1048-9

GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.

Mantel P.Y., Kuipers H., Boyman O., Rhyner C., Ouaked N., Rückert B., Karagiannidis C., Lambrecht B.N., Hendriks R.W., Crameri R., Akdis C.A., Blaser K. and Schmidt-Weber CB.

PLoS Biol. 2007 Dec;5(12):e329

Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region.

Mantis N.J., Palaia J., Hessell A.J., Mehta S., Zhu Z., Corthésy B., Neutra M.R., Burton D.R. and Janoff E.N.

J Immunol. 2007 Sep 1;179(5):3144-52

Oxidized low-density lipoproteins activate CD4+ T cell apoptosis in patients with end-stage renal disease through Fas engagement.

Meier P., Spertini F., Blanc E. and Burnier M.

J Am Soc Nephrol. 2007 Jan;18(1):331-42

Studies of a prophylactic HIV-1 vaccine candidate based on modified vaccinia virus Ankara (MVA) with and without DNA priming: Effects of dosage and route on safety and immunogenicity.

Peters B.S., Jaoko W., Vardas E., Panayotakopoulos G., Fast P., Schmidt C., Gilmour J., Bogoshi M., Omosa-Manyonyi G., Dally L., Klavinskis L., Farah B., Tarragona T., Bart P.-A., Robinson A., Pieterse C., Stevens W., Thomas R., Barin B., McMichaelk A.J.,

Vaccine. 2007 Mar 1;25(11):2120-7

Large vessel vasculitis: giant cell arteritis and Takayasu arteritis.

Petitpierre S., Bart P.-A., Leimgruber A., Prior J. and Spertini F.

Rev Med Suisse. 2007 Apr 25;3(108):1056-60, 1062-3

Allergy to betalactam antibiotics in children: a prospective follow-up study in retreated children after negative responses in skin and challenge tests.

Ponvert C., Weilenmann C., Wassenberg J., Walecki P., Bourgeois M.L., de Blic J. and Scheinmann P.

Allergy. 2007 Jan;62(1):42-6

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8+ T cell responses.

Precopio M.L., Betts M.R., Parrino J., Price D.A., Gostick E., Ambrozak D.R., Asher T.E., Douek D.C., Harari A., Pantaleo G., Bailer R., Graham B.S., Roederer M. and Koup R.A.

J Exp Med. 2007 Jun 11;204(6):1405-16

alpha(1)beta(1) integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.

Conrad C., Boyman O., Tonel G., Tun-Kyi A., Laggner U., de Fougerolles A., Kotelianski V., Gardner H. and Nestle F.O.

Nat Med. 2007 Jul;13(7):836-42

2006

Omics for prevention: gene, protein and metabolite profiling to better understand individual disposition to disease.

Affolter M., Bergonzelli G.E., Blaser K., Blum-Sperisen S., Corthésy B., Fay L.B., Garcia-Rodenas C., Lopes L.V., Marvin-Guy L., Mercenier A., Mutch D.M., Panchaud A., Raymond F., Schmidt-Weber C., Schumann A., Spertini F., Williamson G. and Kussmann M.

Nestle Nutr Workshop Ser Pediatr Program. 2006;57:247-50; discussion 250-5

Glycans on secretory component participate in innate protection against mucosal pathogens.

Perrier C., Sprenger N. and Corthésy B.

J Biol Chem. 2006 May 19;281(20):14280-7

Anaphylaxie p182-183; Aspergillose allergique bronchopulmonaire p409; Urticaire et angioedème p410; Allergie aux hyménoptères p411; Maladie de Widal p420; Allergie à la Pénicilline p1021.

Leimgruber A.

P. Furger. SURF Guide thérapeutique de Médecine interne et Diagnostic différentiel selon INVESTI-MED. Editions D & F GMBH, Suisse 2006, p1-1328.

Allergo-immunology.

Leimgruber A.

Rev Med Suisse. 2006 Jan 11;2(48):89-92

Specific interferon-gamma assays: a modern tool for tuberculosis diagnosis.

Lurati Ruiz F., Audran R., Harari A. and Spertini F.

Rev Med Suisse. 2006 Apr 19;2(62):1042, 1044-7

Fondaparinux is a safe alternative in case of heparin intolerance during pregnancy.

Mazzolai L., Hohlfeld P., Spertini F., Hayoz D., Schapira M. and Duchosal M.A.

Blood. 2006 Sep 1;108(5):1569-70

Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.

Pantaleo G. and Harari A.

Nat Rev Immunol. 2006 May;6(5):417-23

Recurrent ibuprofen-induced aseptic meningitis: evidence against an antigen-specific immune response.

Periard D., Mayor C., Aubert V. and Spertini F.

Neurology. 2006 Aug 8;67(3):539-40

Clinical proteomics: Study of a cryogel.

Robert D., Barelli S., Crettaz D., Bart P.-A., Schifferli J.A., Betticher D. and Tissot J.-D.

Proteomics. 2006 Jul;6(13):3958-60

Functional signatures of protective antiviral T-cell immunity in human virus infections.

Harari A., Dutoit V., Cellerai C., Bart P.-A., Du Pasquier R.A. and Pantaleo G.

Immunol Rev. 2006 Jun;211:236-54

MHC class II compartment subtypes: structure and function.

Stern L.J., Potolicchio I. and Santambrogio L.

Curr Opin Immunol. 2006 Feb;18(1):64-9

Favourable outcome of progressive multifocal leukoencephalopathy in two patients with dermatomyositis.

Vulliemoz S., Lurati-Ruiz F., Borruat F.X., Delavelle J., Koralnik I.J., Kuntzer T., Bogousslavsky J., Picard F., Landis T. and Du Pasquier R.A.

J Neurol Neurosurg Psychiatry. 2006 Sep;77(9):1079-82

Multicenter evaluation of a new 4th generation HIV screening assay elecsys HIV combi.

Weber B., Orazi B., Raineri A., Thorstensson R., Bürgisser P., Mühlbacher A., Areal C., Eiras A., Villaescusa R., Camacho R., Diogo I., Roth H.-J., Zahn I., Bartel J., Bossi V., Piro F., Atamasirikul K., Permpikul P., Webber L. and Singh S.

Clin. Lab. 2006, 52:463-473.

Sinnlose Allergietests: Stellungnahme der Fachkommission der Schweizerischen Gesellschaft für Allergologie und Immunologie (SGAI) zur IgG/IG4-Bestimmung gegen Nahrungsmittel.

Wüthrich B., Frei P.C., Bircher A., Dayer E., Hauser C., Pichler W., Schmid-Grendelmeier P., Spertini F., Olgiati D. and Müller U.

Pipette Swiss Laboratory Medicine 2006, 2:9-12.

Pathogenic mechanisms in systemic sclerosis and their therapeutical consequences. Part 1: pathogenesis.

Zuber J.-P., Chizzolini C., Leimgruber A., Bart P.-A. and Spertini F.

Rev Med Suisse. 2006 Apr 19;2(62):1052-7

Pathogenic mechanisms in systemic sclerosis and their therapeutical consequences. Part 2: treatment.

Zuber J.-P., Chizzolini C., Leimgruber A., Bart P.-A. and Spertini F.

Rev Med Suisse. 2006 Apr 19;2(62):1058, 1060-6

Immunological basis of systemic sclerosis.

Zuber J.-P. and Spertini F.

Rheumatology (Oxford). 2006 Oct;45 Suppl 3:iii23-5

Immunité et neurodégénérescence: nouveaux concepts dans la sclérose en plaques.

Lalive P.H., Schluep M., Chofflon M. and Du Pasquier R.

Rev Med Suisse. 2006 May 3;2(64):1166-8, 1170

Role of HIV-1-specific CD4 T cells.

Harari A., Cellerai C. and Pantaleo G.

Curr Opin HIV AIDS. 2006 Jan;1(1):22-7

Molecular defects of the C7 gene in two patients with complement C7 deficiency.

Barroso S., Rieubland C., Jose alvarez A., Lopez-Trascasa M., Bart P.-A., Nunez-Roldan A. and Sanchez B.

Immunology. 2006 Jun;118(2):257-60

Interplay of cellular and humoral immune responses against BK virus in kidney transplant recipients with polyomavirus nephropathy.

Chen Y., Trofe J., Gordon J., Du Pasquier R.A., Roy-Chaudhury P., Kuroda M.J., Woodle E.S., Khalili K. and Koralnik I.J.

J Virol. 2006 Apr;80(7):3495-505

Clinical studies of experimental vaccines.

Bart P.-A., Harari A. and Pantaleo G.

Curr Opin HIV AIDS. 2006 Jul;1(4):286-93

Immune-based interventions in HIV infection: doing the right studies, getting the right answers.

Bart P.-A. and Pantaleo G.

AIDS. 2006 Feb 28;20(4):617-8

Understanding the Raynaud's phenomenon: towards a better treatment.

Bart P.-A. and Waeber B.

Rev Med Suisse. 2006 Jan 11;2(48):93-6

Specific effects of denaturation, hydrolysis and exposure to Lactococcus lactis on bovine beta-lactoglobulin transepithelial transport, antigenicity and allergenicity.

Bernasconi E., Fritsché R. and Corthésy B.

Clin Exp Allergy. 2006 Jun;36(6):803-14

A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells.

Boyman O., Cho J.H., Tan J.T., Surh C.D. and Sprent J.

J Exp Med. 2006 Jul 10;203(7):1817-25

Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease.

Boyman O., Surh C.D. and Sprent J.

Expert Opin Biol Ther. 2006 Dec;6(12):1323-31

CpG oligodeoxynucleotides activate dendritic cells in vivo and induce a functional and protective vaccine immunity against a TERT derived modified cryptic MHC class I-restricted epitope.

Cornet S., Menez-Jamet J., Lemonnier F., Kosmatopoulos K. and Miconnet I.

Vaccine. 2006 Mar 10;24(11):1880-8

Patient with HIV-HCV co-infections.

Furger P., Berger A., Bounameaux H., Burri H., Buclin T., Fumeaux T., Leimgruber A., Sarasin F., Schmidt P, Martin Suter T., Pruvot E., Reichart M. and Zanetti G.

Editions D & F GMBH, Suisse 2006, p1-564.

Optimal organization of a polypeptide-based candidate cancer vaccine composed of cryptic tumor peptides with enhanced immunogenicity.

Cornet S., Miconnet I., Menez J., Lemonnier F. and Kosmatopoulos K.

Vaccine. 2006 Mar 15;24(12):2102-9

Rotavirus anti-VP6 secretory IgA contributes to protection via intracellular neutralization but not via immune exclusion.

Corthésy B., Benureau Y., Perrier C., Fourgeux C., Parez N., Greenberg H. and Schwartz-Cornil I.

J Virol. 2006 Nov;80(21):10692-9

In Process Citation.

Dayer J.-M. and Spertini F.

Rev Med Suisse. 2006 Apr 19;2(62):1019

High prevalence of secondary resistance mutations in Venezuelan HIV-1 isolates.

Dieudonne M., Garzaro D., Torres J., Naranjo L., Suàrez J.A., Castro J., Martínez N., Castro E., Berrueta L., Salmen S., Devesa M., Rangel H.R. and Pujol F.H.

Invest Clin. 2006 Mar;47(1):27-34

JC virus induces a vigorous CD8+ cytotoxic T cell response in multiple sclerosis patients.

Du Pasquier R.A., Stein M.C., Lima M.A., Dang X., Jean-Jacques J., Zheng Y., Letvin N.L. and Koralnik I.J.

J Neuroimmunol. 2006 Jul;176(1-2):181-6

Anti-HLA antibody repertoire after IVIg infusion in highly sensitised patients waiting for kidney transplantation.

Ferrari-Lacraz S., Aubert V., Buhler L., Pascual M., Andresen I., Binet I., Martin P.-Y. and Villard J.

Swiss Med Wkly. 2006 Oct 28;136(43-44):696-702

Prevention of cryoprecipitation during cardiopulmonary bypass in a patient with HIV-HCV co-infections.

Fontana M., Ruchat P., Horisberger J., Aubert V., Mayor C. and Spertini F.

Perfusion. 2006 Dec;21(5):263-5

Food products and allergy development, prevention and treatment.

Zuercher A.W., Fritsche R., Corthésy B. and Mercenier A.

Curr Opin Biotechnol. 2006 Apr;17(2):198-203

2005

Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen.

Audran R., Cachat M., Lurati F., Soe S., Leroy O., Corradin G., Druilhe P. and Spertini F.

Infect Immun. 2005 Dec;73(12):8017-26

La Triade de Widal (asthme-polypose nasale-intolérance à l'aspirine) : une anomalie du métabolisme inflammatoire.

Leimgruber A.

Rev Med Suisse. 2005 Jan 5;1(1):15-8

Sarcoidosis: new therapeutic and pathogenic aspects for an "old" disease.

Zuber J.-P., Spertini F., Leimgruber A. and Bart P.-A.

Rev Med Suisse. 2005 Apr 13;1(15):1026, 1029-34, 1036-8

HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells.

Zimmerli S.C., Harari A., Cellerai C., Vallelian F., Bart P.-A. and Pantaleo G.

Proc Natl Acad Sci U S A. 2005 May 17;102(20):7239-44

Allergo-immunology.1. Eosinophiles: old knowledge... and new pathologies.

Spertini F.

Rev Med Suisse. 2005 Jan 5;1(1):10-4

About the article "Sports and immunology-allergology.

Spertini F., Dayer J.M. and Gremion G.

Rev Med Suisse. 2005 Apr 13;1(15):987-8

Traitements immunomodulateurs/suppresseurs en neurologie.

Schluep M., Chofflon M., Kuntzer T. and Du Pasquier R.

Rev Med Suisse. 2005 May 4;1(18):1229-32

Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression.

Roger T., Miconnet I., Schiesser A.L., Kai H., Miyake K. and Calandra T.

Biochem J. 2005 Apr 15;387(Pt 2):355-65

Pyelonephritic Escherichia coli expressing P fimbriae decrease immune response of the mouse kidney.

Rice J.C., Peng T., Spence J.S., Wang H.Q., Goldblum R.M., Corthésy B. and Nowicki B.J.

J Am Soc Nephrol. 2005 Dec;16(12):3583-91

Immune responses induced by lower airway mucosal immunisation with a human papillomavirus type 16 virus-like particle vaccine.

Nardelli-Haefliger D., Lurati F., Wirthner D., Spertini F., Schiller J.T., Lowy D.R., Ponci F. and De Grandi P.

Vaccine. 2005 May 25;23(28):3634-41

Standardization of cytokine flow cytometry assays.

Maecker H.T., Rinfret A., D'Souza P., Darden J., Roig E., Landry C., Hayes P., Birungi J., Anzala O., Garcia M., Harari A., Frank I., Baydo R., Baker M., Holbrook J., Ottinger J., Lamoreaux L., Epling C.L., Sinclair E., Suni M.A., Punt K., Calarota S., El

BMC Immunol. 2005 Jun 24;6:13

Predictive value of antineutrophil cytoplasmic antibodies in small-vessel vasculitis.

Lurati Ruiz F. and Spertini F.

J Rheumatol. 2005 Nov;32(11):2167-72

New therapeutic strategies in ANCA-associated systemic vasculitis.

Lurati Ruiz F. and Bart P.-A.

Rev Med Suisse. 2005 Jan 5;1(1):19-23

Loss of HIV-1-specific T cell proliferation in chronic HIV-1 infection: cause or consequence of viral replication ?

Lichterfeld M., Pantaleo G. and Altfeld M.

AIDS. 2005 Jul 22;19(11):1225-7

Differential insertion of GPI-anchored GFPs into lipid rafts of live cells.

Legler D.F., Doucey M.-A., Schneider P., Chapatte L., Bender F.C. and Bron C.

FASEB J. 2005 Jan;19(1):73-5

Trends of HIV-1 molecular epidemiology in Venezuela: introduction of subtype C and identification of a novel B/C mosaic genome.

Castro E., Moreno M., Deibis L., de Pérez G., Salmen S. and Berrueta L.

J Clin Virol. 2005 Mar;32(3):257-8

Functional heterogeneity of memory CD4 T cell responses in different conditions of antigen exposure and persistence.

Harari A., Vallelian F., Meylan P. and Pantaleo G.

J Immunol. 2005 Jan 15;174(2):1037-45

Understanding what makes a good versus a bad vaccine.

Harari A. and Pantaleo G.

Eur J Immunol. 2005 Sep;35(9):2528-31

Wegener Granulomatosis presenting with haemorragic stroke in a young adult.

Granziera C., Michel P., Rossetti A.O., Lurati F., Reymond S. and Bogousslavsky J.

J Neurol. 2005 May;252(5):615-6

Syndrome oral croisé et allergies alimentaires.

Fontana M., Spertini F., Bart P.-A. and Leimgruber A.

Rev Med Suisse. 2005 Apr 13;1(15):1010, 1013-7

Dermite caustique du visage après activation d'un air-bag: à propos d'un cas.

Fontana M., Delarive P. and Panizzon R.G.

Ann Dermatol Venereol. 2005 Feb;132(2):164-5

Secretory IgA possesses intrinsic modulatory properties stimulating mucosal and systemic immune responses.

Favre L., Spertini F. and Corthésy B.

J Immunol. 2005 Sep 1;175(5):2793-800

Intravenous immunoglobulin replacement prevents severe and lower respiratory tract infections, but not upper respiratory tract and non-respiratory infections in common variable immune deficiency.

Favre O., Leimgruber A., Nicole A. and Spertini F.

Allergy. 2005 Mar;60(3):385-90

Differences in HCV-specific T cell responses between chronic HCV infection and HIV/HCV co-infection.

Dutoit V., Ciuffreda D., Comte D., Gonvers J.J. and Pantaleo G.

Eur J Immunol. 2005 Dec;35(12):3493-504

Presence of JC virus-specific CTL in the cerebrospinal fluid of PML patients: rationale for immune-based therapeutic strategies.

Du Pasquier R.A., Autissier P., Zheng Y., Jean-Jacques J. and Koralnik I.J.

AIDS. 2005 Dec 2;19(18):2069-76

A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum.

Druilhe P., Spertini F., Soesoe D., Corradin G., Mejia P., Singh S., Audran R., Bouzidi A., Oeuvray C. and Roussilhon C.

PLoS Med. 2005 Nov;2(11):e344

Skin tests in allergology: really so simple ?

Deruaz C.A., von Feilitzen A., Leimgruber A., Bart P.-A. and Spertini F.

Rev Med Suisse. 2005 Apr 13;1(15):997-1002

Oral immunization of mice with lactic acid bacteria producing Helicobacter pylori urease B subunit partially protects against challenge with Helicobacter felis.

Corthésy B., Boris S., Isler P., Grangette C. and Mercenier A.

J Infect Dis. 2005 Oct 15;192(8):1441-9

Tests d'allergie inutiles. Prise de position de la Commission de spécialité de la Société Suisse d'Allergologie et Immunologie (SSAI) sur les déterminations des IgG/IgG4 contre les aliments.

Wüthricha B., Frei P.C., Bircher A., Dayer E., Hauser C., Pichler W., Schmid-Grendelmeierg P., Spertini F., Olgiati D. and Müller U.

Bulletin des médecins suisses 2005, 86:1569-1571.

2004

Le point sur l'allergie: mécanismes et diagnostic in vitro.

Aubert V.

Labmed 2004, 31:458-462.

Childhood and malaria vaccines combined in biodegradable microspheres produce immunity with synergistic interactions.

Peyre M., Audran R., Estevez F., Corradin G., Gander B., Sesardic D. and Johansen P.

J Control Release. 2004 Oct 19;99(3):345-55

Immunology. Keeping the gut microflora at bay.

Kraehenbuhl J.P. and Corbett M.

Science. 2004 Mar 12;303(5664):1624-5

Vasculites cutanées : les implications en immunologie clinique.

Lapointe A.-L., Leimgruber A., Spertini F., Künzle N., Laffitte E. and Bart P.-A.

Méd. & Hyg. 2004, 62:430-436.

Médication.

Leimgruber A.

Le Guide Suisse des allergies. Edition Mancassola, Le Mont-sur-Lausanne 2004, 4.3:109-112.

Que doit retenir le praticien des immunodéficiences primaires ?

Lurati Ruiz F., Bart P.-A., Hofer M., Périard D., Leimgruber A. and Spertini F.

Méd. & Hyg. 2004, 62:451-458.

Dendritic cells: the host Achille's heel for mucosal pathogens ?

Niedergang F., Didierlaurent A., Kraehenbuhl J.P. and Sirard J.C.

Trends Microbiol. 2004 Feb;12(2):79-88

De novo T-cell generation in patients at different ages and stages of HIV-1 disease.

Nobile M., Correa R., Borghans J.A., D'Agostino C., Schneider P., De Boer R.J. and Pantaleo G.

Blood. 2004 Jul 15;104(2):470-7

Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know.

Pantaleo G. and Kroup R.A.

Nat Med. 2004 Aug;10(8):806-10

Le syndrome des antiphospholipides.

Périard D., Bart P.-A., Deruaz C.A., Spertini F. and Leimgruber A.

Méd. & Hyg. 2004, 62:438-442.

Targeting of secretory IgA to Peyer's patch dendritic cells and T cells following transport by intestinal M cells.

Rey J., Garin N., Spertini F. and Corthésy B.

J Immunol. 2004 Mar 1;172(5):3026-33

Elevation of myoinositol is associated with disease containment in progressive multifocal leukoencephalopathy.

Katz-Brull R., Lenkinski R.E., Du Pasquier R.A. and Koralnik I.J.

Neurology. 2004 Sep 14;63(5):897-900

How the gut links innate and adaptive immunity.

Rumbo M., Anderle P., Didierlaurent A., Sierro F., Debard N., Sirard J.C. and Kraehenbuhl J.P.

Ann N Y Acad Sci. 2004 Dec;1029:16-21

Lymphotoxin ß receptor signaling induces the chemokine CCL20 in intestinal epithelium.

Rumbo M., Sierro F., Debard N., Kraehenbuhl J.P. and Finke D.

Gastroenterology. 2004 Jul;127(1):213-23

Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS.

Scherer A., Frater J., Oxenius A., Agudelo J., Price D.A., Günthard H.F., Barnardo M., Perrin L., Hirschel B., Phillips R.E., McLean A.R. and the Swiss HIV Cohort Study.

Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12266-70

Désensibilisation.

Spertini F.

Le Guide Suisse des allergies. Edition Mancassola, Le Mont-sur-Lausanne 2004, 4.4:113-117.

Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signaling events in human activated T cells.

Spertini F., Perret-Menoud V., Barbier N., Chatila T., Barbey C. and Corthésy B.

Immunology. 2004 Dec;113(4):441-52

Zwitterionic polysaccharides stimulate T cells with no preferential Vbeta usage and promote anergy resulting in protection against experimental abscess formation.

Stingele F., Corthésy B., Kusy N., Porcelli S.A., Kasper D.L. and Tzianabos A.O.

J Immunol. 2004 Feb 1;172(3):1483-90

Long-term efficacy and safety of atazanavir with stavudine and lamivudine in patients previously treated with nelfinavir or atazanavir.

Wood R., Phanuphak P., Cahn P., Pokrovskiy V., Rozenbaum W., Pantaleo G., Sension M., Murphy R., Mancini M., Kelleher T., and Giordano M.

J Acquir Immune Defic Syndr. 2004 Jun 1;36(2):684-92

HIV-1 co/super-infection in intravenous drug users.

Yerly S., Jost S., Monnat M., Telenti A., Cavassini M., Chave J.-P., Kaiser L., Bürgisser P., Perrin L. and the Swiss HIV Cohort Study.

AIDS. 2004 Jul 2;18(10):1413-21

Infection VIH: dix points clefs pour la prise en charge par les praticiens.

Khonkarly M.B., Merlani G., Halfon P., Bellini C., Pellet A., Kazadi K., Cavassini M. and Tarr P.

Méd. & Hyg. 2004, 62:862-868.

Isolation of dendritic cells from mouse Peyer's patches using magnetic cell sorting.

Kadaoui K.A. and Corthésy B.

Customer Report MACS & more 2004, 8:10-13.

Long-term persistence of HIV-1 vaccine-induced CD4+CD45RA-CD62L-CCR7- memory T-helper cells.

Balla-Jhagjhoorsingh S.S., Koopman G., Mooij P., Koornstra W., McCormack S., Weber J., Pantaleo G., Heeney J.L.

AIDS. 2004 Apr 9;18(6):837-48

Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response.

Didierlaurent A., Ferrero I., Otten L.A., Dubois B., Reinhardt M., Carlsen H., Blomhoff R., Akira S., Kraehenbuhl J.P. and Sirard, J.C.

J Immunol. 2004 Jun 1;172(11):6922-30

Intranasal treatment with ovalbumin but not the major T cell epitope ovalbumin 323-339 generates interleukin-10 secreting T cells and results in the induction of allergen systemic tolerance.

Barbey C., Donatelli-Dufour N., Batard P., Corradin G. and Spertini F.

Clin Exp Allergy. 2004 Apr;34(4):654-62

Human polymeric IgA is superior to IgG and single-chain Fv of the same monoclonal specificity to inhibit urease activity associated with Helicobacter pylori.

Berdoz J. and Corthésy B.

Mol Immunol. 2004 Aug;41(10):1013-22

Prevalence of human T-cell leukemia virus types I and II in Switzerland.

Böni J., Bisset L.R., Burckhardt J.J., Joller-Jemelka H.I., Bürgisser P., Perrin L., Gorgievski M., Erb P., Fierz W., Piffaretti J.-C., Schüpbach J. and the Swiss HIV Cohort Study.

J Med Virol. 2004 Feb;72(2):328-37

Lung immunity: necessity is the mother of induction.

Corbett M. and Kraehenbuhl JP.

Nat Med. 2004 Sep;10(9):904-5

Medicinal application of long synthetic peptide technology.

Corradin G., Spertini F. and Verdini A.

Expert Opin Biol Ther. 2004 Oct;4(10):1629-39

Latex: de l’allergie professionnelle au syndrome latex-fruit.

Deruaz C.A., Lapointe A.-K., Bart P.-A., Leimgruber A. and Spertini F.

Méd. & Hyg. 2004, 62:421-426.

Levocetirizine better protects than desloratadine in a nasal provocation with allergen.

Deruaz C., Leimgruber A., Berney M., Pradervand E. and Spertini F.

J Allergy Clin Immunol. 2004 Apr;113(4):669-76

Reply to: Modern histamine H1-receptor antagonists in the unified airway.

Deruaz C. and Spertini F.

J. Allergy Clin. Immunol. 2004, 114:698-699.

Attenuated poxviruses expressing a synthetic HIV protein stimulate HLA-A2-restricted cytotoxic T-cell responses.

Didierlaurent A., Ramirez J.C., Gherardi M., Zimmerli S.C., Graf M., Acha-Orbea H., Pantaleo G., Wagner R., Esteban M., Kraehenbuhl J.-P. and Sirard J.C.

Vaccine. 2004 Sep 3;22(25-26):3395-403

Modulation of allergic responses in mice by using biodegradable poly(lactide-co-glycolide) microspheres.

Jilek S., Walter E., Merkle H.P. and Corthésy B.

J Allergy Clin Immunol. 2004 Oct;114(4):943-50

Detection of JC virus-specific cytotoxic T lymphocytes in healthy individuals.

Du Pasquier R.A., Schmitz J.E., Jean-Jacques J., Zheng Y., Gordon J., Khalili K., Letvin N.L. and Koralnik I.J.

J Virol. 2004 Sep;78(18):10206-10

Spezifische Immuntherapie in der Schweiz - sublingual oder subkutan ? Immunothérapie spécifique en Suisse - sublinguale ou sous-cutanée ?

Eng P., Hauser C., Helbling A., Schmid-Grendelmeier P., Spertini F. and Bircher A.

Schweiz Med. Forum 2004, 4:1269-1276.

Eotaxin-1 (CCL11) up-regulation in tears during seasonal allergic conjunctivitis.

Eperon S., Sauty A., Lanz R., Leimgruber A., Lurati F. and Guex-Crosier Y.

Graefes Arch Clin Exp Ophthalmol. 2004 Nov;242(11):966-70

Prevention of cryoglobulins during extracorporeal circulation in a patient with HIV-HCV co-infections.

Fontana M., Ruchat P., Horisberger J., Aubert V., Mayor C. and Spertini F.

Swiss Med. Wkly 2004, 134 (suppl. 140):S8.

Functional characterization of HIV-1-specific CD4 T cells.

Harari A. and Pantaleo G.

EPHIS Book, 2004.

Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy.

Harari A., Petitpierre F., Vallelian F. and Pantaleo G.

Blood. 2004 Feb 1;103(3):966-72

Phenotypic heterogeneity of antigen-specific CD4 T cells under different conditions of antigen persistence and antigen load.

Harari A., Vallelian F. and Pantaleo G.

Eur J Immunol. 2004 Dec;34(12):3525-33

Cytomegalovirus (CMV)-specific cellular immune responses.

Harari A., Zimmerli S. and Pantaleo G.

Hum Immunol. 2004 May;65(5):500-6

Infrequent transmission of HIV-1 drug-resistant variants.

Yerly S., Jost S., Telenti A., Flepp M., Kaiser L., Chave J.-P., Vernazza P., Battegay M., Furrer H., Chanzy B., Bürgisser P., Rickenbach M., Gebhardt M., Bernard M.-C., Perneger T., Hirschel B., Perrin L. and the Swiss HIV Cohort Study.

Antivir Ther. 2004 Jun;9(3):375-84

2003

Ethique et laboratoire.

Aubert V.

Croix-Rouge suisse 2003, Journal dossier 2, septembre:20-22.

Allergologie et immunologie clinique. Allergie et anaphylaxie : nouveautés thérapeutiques.

Leimgruber A.

Méd. & Hyg. 2003, 61:12-13.

Indications to specific immunotherapy in asthma.

Spertini, F.

Asthme de l'enfant et de l'adulte, Foundation for Education and Research in Allergy and Immunology, 2003, p 152-161.

Désensibilisation.

Spertini, F.

Le Guide Suisse des allergies. Edition Mancassola, Le Mont-sur-Lausanne, 2003, 4.4:116-121.

Augmentation de la fréquence des allergies : un problème de société.Plantes, Pollens et Allergies, p 124-131

Spertini F.

Plantes, Pollens et Allergies 2003, p 124-13.

Allergologie et immunologie clinique. Régulation de la réponse allergique et prévention primaire : stratégies parallèles ?

Spertini F. and Longaretti C.

Méd. & Hyg. 2003, 61:8-11.

La formation continue : plus qu'un simple enseignement, un enjeu politique.

Spertini F. and Dayer J.-M.

Méd. & Hyg. 2003 , 61:795-796.

Novel functions of the polymeric Ig receptor: well beyond transport of immunoglobulins.

Phalipon A. and Corthésy B.

Trends Immunol. 2003 Feb;24(2):55-8

Connectivite mixte : mise au point.

Perrin E., Leimgruber A., Spertini F. and Bart P.-A.

Méd. & Hyg. 2003, 61:823-828.

Effects of CCR5-Delta32 and CCR2-64I alleles on HIV-1 disease progression: the protection varies with duration of infection.

Mulherin S.A., O'Brien T.R., Ioannidis J.P., Goedert J.J., Buchbinder S.P., Coutinho R.A., Jamieson B.D., Meyer L., Michael N.L., Pantaleo G., Rizzardi G.P., Schuitemaker H., Sheppard H.W., Theodorou I.D., Vlahov D. and Rosenberg P.S; International Meta-A

AIDS. 2003 Feb 14;17(3):377-87

OM-174, a new adjuvant with a potential for human use, induces a prospective reponse when administred with the synthetic C-terminal fragment 242-310 from the circumsporozoite protein of Plasmodium berghei

Meraldi V., Audran R., Romero J.F., Brossars V., Bauer J., Lopez J.A. and Corradin G.

Vaccine. 2003 Jun 2;21(19-20):2485-91

Dual Transplant of Marginal kidneys. Case report and review of literature.

Matter M., Venetz J.-P., Aubert V., Gachet C., Burnier M. and Barbey F.

Swiss Surg. 2003;9(5):213-5

Intérêt des anticorps anti-cytoplasme des neutrophiles (ANCA) en clinique.

Lurati Ruiz F., Leimgruber A., Bart P.-A. and Spertini F.

Méd. & Hyg. 2003, 61:830-834.

The human polymeric immunoglobulin receptor binds to Streptococcus pneumoniae via domains 3 and 4.

Lu L., Lamm M.E., Li H., Corthésy B. and Zhang J.R.

J Biol Chem. 2003 Nov 28;278(48):48178-87

Médication.

Leimgruber A.

Le Guide Suisse des allergies. Edition Mancassola, Le Mont-sur-Lausanne 2003, p. 110-115.

Les manifestations cliniques de l'allergie pollinique et leur traitement.

Leimgruber A.

Plantes, Pollens et Allergies 2003, p 72-83.

Medicine. The need for a global HIV vaccine enterprise.

Klausner RD., Fauci AS., Corey L., Nabel GJ., Gayle H., Berkley S., Haynes BF., Baltimore D., Collins C., Douglas RG., Esparza J., Francis DP., Ganguly NK., Gerberding JL., Johnston MI., Kazatchkine MD., McMichael AJ., Makgoba MW., Pantaleo G., Piot P., S

Science. 2003 Jun 27;300(5628):2036-9

Encapsulation of peptides in biodegradable microspheres prolongs their MHC class-I presentation by dendritic cells and macrophages in vitro.

Audran R., Peter K., Dannull J., Men Y., Scandella E., Groettrup M., Gander B. and Corradin G.

Vaccine. 2003 Mar 7;21(11-12):1250-5

CD4 T-lymphocyte recovery in individuals with advanced HIV-1 infection receiving potent antiretroviral therapy for 4 years: the Swiss HIV Cohort Study.

Kaufmann G.R., Perrin L., Pantaleo G., Opravil M., Furrer H., Telenti A., Hirschel B., Ledergerber B., Vernazza P., Bernasconi E., Rickenbach M., Egger M. and Battegay M.

Arch Intern Med. 2003 Oct 13;163(18):2187-95

Les uvéites: approche diagnostique multi-disciplinaire actualisée à l'usage de l'ophtalmologue et de l'interniste. Partie 2 : investigations systémiques en cas duvéite et apport de linterniste.

Herbort C.P., Tao Tran V., Auer C. and Spertini F.

Méd. & Hyg. 2003, 61:1519-1522.

Les uvéites: approche diagnostique multi-disciplinaire actualisée à l'usage de l'ophtalmologue et de l'interniste. Partie 1 : la démarche diagnostique en ophtlamologie.

Herbort C.P., Tao Tran V., Auer C. and Spertini F.

Méd. & Hyg. 2003, 61:1371-1380.

Comment évaluer le risque oncologique d'un patient souffrant de dermatomyosite ?

Gainon J., Bart P.-A. and Waeber G.

Praxis 2003, 92:1734-1739.

Allergen-specific T-cell tolerance induction with allergen-derived long synthetic peptide results of a phase I trial.

Fellrath J.-M., Kettner A., Dufour N., Frigerio C., Schneeberger D., Leimgruber A., Corradin G. and Spertini F.

J Allergy Clin Immunol. 2003 Apr;111(4):854-61

Simplified procedure to recover recombinant antigenized secretory IgA to be used as a vaccine vector.

Favre L., Spertini F. and Corthésy B.

J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Mar 25;786(1-2):143-51

Plantes, Pollens et Allergies.

Felber F., Clot B., Leimgruber A. and Spertini F.

Presse de l'Université de Neuchâtel. 2003, p. 208.

Approche anti-inflammatoire de la rhinite allergique.

Deruaz C., Bart P.-A., Spertini F. and Leimgruber A.

Méd. & Hyg. 2003, 61:836-840.

Presence of Gal-alpha1,3Gal epitope on xenogeneic lines: implications for cellular gene therapy based on the encapsulation technology.

Deglon N., Aubert V., Spertini F., Winkel L. and Aebischer P.

Xenotransplantation. 2003 May;10(3):204-13

Passive immunity in Helicobacter-challenged neonatal mice conferred by immunized dams lasts until weaning.

Corthésy-Theulaz I., Corthésy B., Bachmann D., Velin D. and Kraehenbuhl J.-P.

Infect Immun. 2003 Apr;71(4):2226-9

Recombinant secretory immunoglobulin A in passive immunotherapy: linking immunology and biotechnology.

Corthésy B.

Curr Pharm Biotechnol. 2003 Feb;4(1):51-67

Atlas.

Clot B., Felber F., Leimgruber A. and Spertini F.

Plantes, Pollens et Allergies 2003, p.132-193.

Allergologie et immunologie clinique. Les immunosuppresseurs dans les maladies auto-immunes : nouveautés.

Bart P.-A.

Méd. & Hyg. 2003, 61:14-20.

Formation en Médecine Interne : de l'utilité des Case Reports.

Bart P.-A., Lamy O., Vollenweider P. and Waeber G.

Praxis 2003, 92:1711-1711.

Périartérite noueuse et hépatite C : association fortuite ?

Zuber J.-P., Deruaz C., Lobrinus J.A., Waeber G. and Bart P.-A.

Praxis 2003, 92:1717-1725.

2002

Behcet's disease in Western Switzerland: epidemiology and analysis of ocular involvement.

Ambresin A., Tran T., Spertini F. and Herbort C.

Ocul Immunol Inflamm. 2002 Mar;10(1):53-63

Selective adherence of IgA to murine Peyer's patch M cells: evidence for a novel IgA receptor.

Mantis N.J., Cheung M.C., Chintalacharuvu K.R., Rey J., Corthésy B. and Neutra M.R.

J Immunol. 2002 Aug 15;169(4):1844-51

Transcutaneous immunization using colonization factor and heat-labile enterotoxin induces correlates of protective immunity for enterotoxigenic Escherichia coli.

Yu J., Cassels F., Scharton-Kersten T., Hammond S.A., Hartman A., Angov E., Corthésy B., Alving C. and Glenn G.

Infect Immun. 2002 Mar;70(3):1056-68

Multicenter evaluation of a new automated fourth-generation human immunodeficiency virus screening assay with a sensitive antigen detection module and high specificity.

Weber B., Gurtler L., Thorstensson R., Michl U., Muhlbacher A., Burgisser P., Villaescusa R., Eiras A., Gabriel C., Stekel H., Tanprasert S., Oota S., Silvestre M.J., Marques C., Ladeira M., Rabenau H., Berger A., Schmitt U. and Melchior W.

J Clin Microbiol. 2002 Jun;40(6):1938-46

In vivo kinetics of the immunoglobulin E response to allergen: bystander effect of coimmunization and relationship with anaphylaxis.

Von Garnier C., Astori M., Kettner A., Dufour N., Corradin G. and Spertini F.

Clin Exp Allergy. 2002 Mar;32(3):401-10

The immunoglobulinopathies: From physiopathology to diagnosis.

Tissot J.D., Vu D.H., Aubert V., Schneider P., Vuadens F., Crettaz D. and Duchosal M.A.

Proteomics. 2002 Jul;2(7):813-24

Individualising HIV treatment--pharmacogenetics and immunogenetics.

Telenti A., Aubert V. and Spertini F.

Lancet. 2002 Mar 2;359(9308):722-3

Reduced acute phase response after laparoscopic total extraperitoneal bilateral hernia repair compared to open repair with the Stoppa procedure.

Suter M., Martinet O. and Spertini F.

Surg Endosc. 2002 Aug;16(8):1214-9

Combinaisons thérapeutiques dans l'asthme.

Spertini F. and Sauty A.

Méd. & Hyg. 2002, 60:8-14.

Potential role of immune modulation in the effective long-term control of HIV-1 infection.

Rizzardi G.P., Lazzarin A. and Pantaleo G.

J Biol Regul Homeost Agents. 2002 Jan-Mar;16(1):83-90

Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy.

Rizzardi G.P., Harari A., Capiluppi B., Tambussi G., Ellefsen K., Ciuffreda D., Champagne P., Bart P.-A., Chave J.P., Lazzarin A. and Pantaleo G.

J Clin Invest. 2002 Mar;109(5):681-8

Lymphoscintigraphy in a patient with polyserositis of unknown origin.

Prior J.O., Boubaker A., Spertini F. and Delaloye A.B.

Clin Nucl Med. 2002 Dec;27(12):905-6

Secretory component: a new role in secretory IgA-mediated immune exclusion in vivo.

Phalipon A., Cardona A., Kraehenbuhl J.-P., Edelman L., Sansonetti P.J. and Corthésy B.

Immunity. 2002 Jul;17(1):107-15

La desloratadine, un nouvel antihistaminique : plus puissant ?

Leimgruber A.

Méd. & Hyg. 2002, 60:12-14.

The immunopathogenesis of HIV-1 infection.

Bart P.-A. and Pantaleo G.

In: Infectious Diseases. Cohen & Powderly, London (UK): Mosby.

Analysis of HIV-1- and CMV-specific memory CD4 T-cell responses during primary and chronic infection.

Harari A., Rizzardi G.P., Ellfesen K., Ciuffreda D., Champagne P., Bart P.-A., Kaufmann D., Telenti A., Sahli R., Tambussi G., Kaiser L., Lazzarin A., Perrin L. and Pantaleo G.

Blood. 2002 Aug 15;100(4):1381-7

Antiviral memory T cell responses: correlation with protective immunity and implication for vaccine development.

Harari A., Ellefsen K., Champagne P., Nobile M. and Pantaleo G.

Adv Exp Med Biol. 2002;512:155-64

Spare non-occupational HIV post-exposure prophylaxis by active contacting and testing of the source person.

Greub G., Gallant S., Zurn P., Vannotti M., Bürgisser P., Francioli P., Zanetti G. and Telenti A.

AIDS. 2002 May 24;16(8):1171-6

Transepithelial transport of HIV-1 by M cells is receptor-mediated.

Fotopoulos G., Harari A., Michetti P., Trono D., Pantaleo G. and Kraehenbuhl J.-P.

Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9410-4

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study.

Fellay J., Marzolini C., Meaden E.R., Back D.J., Buclin T., Chave J.P., Decosterd L.A., Furrer H., Opravil M., Pantaleo G., Retelska D., Ruiz L., Schinkel A.H., Vernazza P., Eap C.B. and Telenti A.

Lancet. 2002 Jan 5;359(9300):30-6

Distribution and functional analysis of memory antiviral CD8 T cell responses in HIV-1 and cytomegalovirus infections.

Ellefsen K., Harari A., Champagne P., Bart P.-A., Sékaly R.P. and Pantaleo G.

Eur J Immunol. 2002 Dec;32(12):3756-64

In vitro microaerophilic conditions permit to mimic events occurring during in vivo Helicobacter pylori infection, and identify Rho/Ras-associated proteins in cellular signalling.

Cottet S., Corthésy-Theulaz I., Spertini F. and Corthésy B.

J Biol Chem. 2002 Sep 13;277(37):33978-86

Treatment of allergy using DNA vaccination.

Corthésy B.

BioWorld 6 2002, pp. 463-477.

Recombinant secretory immunoglobulin A: from fundamental to applied research in mucosal immunology.

Corthésy B.

Recent Res. Devel. Immunology 2002, 4:463-477.

Recombinant immunoglobulin A: powerful tools for fundamental and applied research.

Corthésy B.

Trends Biotechnol. 2002 Feb;20(2):65-71

Lactobacillus bulgaricus proteinase expressed in Lactococcus lactis is a powerful carrier for cell wall-associated and secreted bovine beta-lactoglobulin fusion proteins.

Bernasconi E., Germond J.E., Delley M., Fritsche R. and Corthésy B.

Appl Environ Microbiol. 2002 Jun;68(6):2917-23

Immunodeficiencies associated with immunosuppressive agents.

Bart P.-A. and Pantaleo G.

In: Infectious Diseases. Cohen & Powderly. London (UK): Mosby.

Thymic selection generates a large T cell pool recognizing a self-peptide in humans.Thymic selection generates a large T cell pool recognizing a self-peptide in humans.

Zippelius A., Pittet M.J., Batard P., Rufer N., de Smedt M., Guillaume P., Ellefsen K., Valmori D., Liénard D., Plum J., MacDonald H.R., Speiser D.E., Cerottini J.-C. and Romero P.

J Exp Med. 2002 Feb 18;195(4):485-94

Last updated on 10/08/2018 at 14:29

Publications

Phase 1 HIV vaccine trial to evaluate the safety and immunogenicity of HIV subtype C DNA and MF59-adjuvanted subtype C Env protein.

Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector.

Human gut microbiota is associated with HIV-reactive immunoglobulin at baseline and following HIV vaccination.

Heterologous Combination of VSV-GP and NYVAC Vectors Expressing HIV-1 Trimeric gp145 Env as Vaccination Strategy to Induce Balanced B and T Cell Immune Responses.

Neurologic complications of acute hepatitis E virus infection.

A Robust Method for Assaying the Immunoreactive Fraction in Nonequilibrium Systems.

The complex challenges of HIV vaccine development require renewed and expanded global commitment.

Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity.

Predictive factors of severe infections in patients with systemic necrotizing vasculitides: data from 733 patients enrolled in five randomized controlled trials of the French Vasculitis Study Group.

Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Antisense Protein (ASP) RNA Transcripts in Patients by Strand-Specific RT-PCR.

Risk of malignancy in patients treated for systemic necrotising vasculitis.

Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis.

Antigenic competition in CD4&lt;sup&gt;+&lt;/sup&gt; T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial.

A model for reticular dysgenesis shows impaired sensory organ development and hair cell regeneration linked to cellular stress.

Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.

Anti-C1q Antibodies as Occurring in Systemic Lupus Erythematosus Could Be Induced by an Epstein-Barr Virus-Derived Antigenic Site.

Nonvascularized human skin chronic allograft rejection.

T-cell exhaustion in HIV infection.

Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8&lt;sup&gt;+&lt;/sup&gt; T lymphocyte exhaustion.

Correction for Kibler et al., "Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC".

Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial.

DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial.

Management of allergy transfer upon solid organ transplantation.

Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania.

Anti-apolipoprotein A-1 autoantibodies correlate with disease activity in systemic lupus erythematosus.

Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement.

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART.

Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells.

Efficacy and Adverse Events During Janus Kinase Inhibitor Treatment of SAVI Syndrome.

Novel Nanofluidic IgE Assay versus a Reference Method: A Real-World Comparison.

The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes.

Corrigendum to "A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles" [Virology 507 (2017) 242-256].

Successful desensitization to pomalidomide in a patient with POEMS syndrome with delayed-type hypersensitivity to immunomodulatory imid drugs.

Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway.

[Side effects of immune checkpoint inhibitors: diagnosis and management].

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance.

The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis.

Multi-arm, multi-stage randomised controlled trials for evaluating therapeutic HIV cure interventions.

Gene therapy for Wiskott-Aldrich syndrome: here to stay.

HIV transmission chains exhibit greater HLA-B homogeneity than randomly expected.

[Autoimmune disorders during chronic human immunodeficiency virus (HIV) infection].

[Allergy to fish].

Davantage de silence.

[From isolated cutaneous vasculitis to systemic disease : a diagnostic approach to purpura in the adult patient].

Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting.

The Fatigue Assessment Scale as a simple and reliable tool in systemic lupus erythematosus: a cross-sectional study.

Detection of antisense protein (ASP) RNA transcripts in individuals infected with human immunodeficiency virus type 1 (HIV-1).

Treatment of chronic non-infectious uveitis and scleritis.

Emergence of drug resistance in the Swiss HIV Cohort Study under potent antiretroviral therapy is observed in socially disadvantaged patients.

Appropriate thiamin pyrophosphate levels are required for acclimation to changes in photoperiod.

A systematic phylogenetic approach to study the interaction of HIV-1 with coinfections, non-communicable and opportunistic diseases.

Viral diversity from next-generation sequencing of HIV-1 samples provides precise estimates of infection recency and time since infection.

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4&lt;sup&gt;+&lt;/sup&gt; T cells from ART-suppressed individuals.

High Number of Potential Transmitters Revealed in a Population-based Systematic Hepatitis C Virus RNA Screening Among Human Immunodeficiency Virus-infected Men Who Have Sex With Men.

Patterns of care for Multiple Sclerosis in a setting of universal care access: A cross-sectional study.

High Cure Rates With Grazoprevir-Elbasvir With or Without Ribavirin Guided by Genotypic Resistance Testing Among Human Immunodeficiency Virus/Hepatitis C Virus-coinfected Men Who Have Sex With Men.

Re-boost immunizations with the peptide-based therapeutic HIV vaccine, Vacc-4x, restores geometric mean viral load set-point during treatment interruption.

[Where are we with oral immunotherapy for food allergy ?]

[Side effects of cancer immunotherapies : important role for the clinical immunologist].

[Risk of treatment failure and therapeutic novelties in asthma].

New therapeutic perspectives to manage refractory immune checkpoint-related toxicities.

Comparative analysis and generation of a robust HIV-1 DNA quantification assay.

Signaling Lymphocytic Activation Molecule Family Member 1 Engagement Inhibits T Cell-B Cell Interaction and Diminishes Interleukin-6 Production and Plasmablast Differentiation in Systemic Lupus Erythematosus.

A severe case of refractory esophageal stenosis induced by nivolumab and responding to tocilizumab therapy.

HIV Infection Functionally Impairs &lt;i&gt;Mycobacterium tuberculosis-&lt;/i&gt;specific CD4 and CD8 T-cell responses.

PERISCOPE: road towards effective control of pertussis.

Importance of routine viral load monitoring: higher levels of resistance at ART failure in Uganda and Lesotho compared with Switzerland.

Antibodies to &lt;i&gt;Chlamydia trachomatis&lt;/i&gt; and reproductive health issues in women with SLE: a case-control study.

Replication-competent NYVAC-KC yields improved immunogenicity to HIV-1 antigens in rhesus macaques, compared to non-replicating NYVAC.

Priming with a potent HIV-1 DNA vaccine frames the quality of immune responses prior to a poxvirus and protein boost.

Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines.

Signaling lymphocyte activation molecule family in systemic lupus erythematosus.

Supplemental parenteral nutrition improves immunity with unchanged carbohydrate and protein metabolism in critically ill patients: The SPN2 randomized tracer study.

Prospective evaluation of the capillaroscopic skin ulcer risk index in systemic sclerosis patients in clinical practice: a longitudinal, multicentre study.

A severe case of neuro-Sjögren's syndrome induced by pembrolizumab.

Effect of national HIV testing recommendations and local interventions on HIV testing practices in a Swiss university hospital: a retrospective analysis between 2012 and 2015.

Autoantibodies Against Albumin in Patients With Systemic Lupus Erythematosus.

Immunogenicity and safety of double versus standard dose of the seasonal influenza vaccine in solid-organ transplant recipients: A randomized controlled trial.

TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs.

Antigenic competition in CD4<sup>+</sup> T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial.

Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8<sup>+</sup> T lymphocyte exhaustion.

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4<sup>+</sup> T cells from ART-suppressed individuals.

HIV Infection Functionally Impairs <i>Mycobacterium tuberculosis-</i>specific CD4 and CD8 T-cell responses.

Antibodies to <i>Chlamydia trachomatis</i> and reproductive health issues in women with SLE: a case-control study.

CD32<sup>+</sup> and PD-1<sup>+</sup> Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals.

Effect of high-intensity versus low-intensity praziquantel treatment on HIV disease progression in HIV and <i>Schistosoma mansoni</i> co-infected patients: a randomised controlled trial.

Hyperglycaemia is inversely correlated with live M. bovis BCG-specific CD4<sup>+</sup> T cell responses in Tanzanian adults with latent or active tuberculosis.

Exploring the effect of vitamin D<sub>3</sub> supplementation on the anti-EBV antibody response in relapsing-remitting multiple sclerosis.

Identification of a novel HLA-B18 allele, B18:119, using sequence-based typing in a caucasoid individual.