Laboratory equipment and available techniques
Our research group has a wide experience in the study of platelet function and coagulation anomalies related to thrombotic and bleeding disorders. The laboratory has complete equipment for investigating complex clinical situations complementing standard hemostasis routine diagnostic tests, as well as for basic and translational research projects.
We developed flow cytometric methods to study platelet activation and procoagulant activity, especially cytosolic ion fluxes and protein phosphorylations.
Thrombin generation assays
We use global hemostasis tests to investigate the correlation of parameters describing thrombin generation, clotting formation and fybrinolisis with phenotypes of patients presenting different state of hemostasis (from patients anticoagulated with DOACs to patients with rare bleeding disorders).
We aim to implement analysis of platelets with fluorescent microscopy coupled with a flow-based system.
Specific hematological and haemostasis assays