MD
Professeur associé UNIL
Médecin chef
Service et laboratoire central d'hématologie
Tél. +41 (0)21 314 4226
Contacter par mail
The research activity of our laboratory is focused on the study of the molecular mechanisms that regulate malignant leukocyte interactions with their microenvironment. We identified selectin ligands expressed by acute myeloid and lymphoblastic leukemia cells and characterized the role of PSGL-1, CD43 and CD44 in supporting myeloblast and lymphoblast interactions with selectins.
Presently, our aims are:
Brunel AS, Wójtowicz A, Lamoth F, Spertini O, Neofytos D, Calandra T, Marchetti O, Bochud PY
Haematologica. 2018 Nov;103(11):e527-e530
Rahmé R, Ades L, Thomas X, Guerci-Bresler A, Pigneux A, Vey N, Raffoux E, Castaigne S, Spertini O, Wittnebel S, Marolleau JP, Damaj G, Bordessoule D, Lejeune J, Chevret S, Fenaux P
Haematologica. 2018 Nov;103(11):e519-e521
Schnegg-Kaufmann A, Feller A, Baldomero H, Rovo A, Manz MG, Gregor M, Efthymiou A, Bargetzi M, Hess U, Spertini O, Chalandon Y, Passweg JR, Stussi G, Arndt V, Bonadies N, NICER Working Group.
Cancer Epidemiol. 2018 Feb;52:55-62
Kritikos A, Spertini O
Blood. 2017 Jul 6;130(1):95
Noetzli J, Gavillet M, Masouridi-Levrat S, Duchosal M, Spertini O
Clin Case Rep. 2017 Aug;5(8):1320-1322
Löwenberg B, Pabst T, Maertens J, van Norden Y, Biemond BJ, Schouten HC, Spertini O, Vellenga E, Graux C, Havelange V, de Greef GE, de Weerdt O, Legdeur MJ, Kuball J, Kooy MV, Gjertsen BT, Jongen-Lavrencic M, van de Loosdrecht AA, van Lammeren-Venema D, H
Blood. 2017 Mar 23;129(12):1636-1645
Gavillet M, Noetzli J, Blum S, Duchosal MA, Spertini O, Lambert JF
Haematologica. 2012 Dec;97(12):1929-31
Boller D, Doepfner KT, De Laurentiis A, Guerreiro AS, Marinov M, Shalaby T, Depledge P, Robson A, Saghir N, Hayakawa M, Kaizawa H, Koizumi T, Ohishi T, Fattet S, Delattre O, Schweri-Olac A, Höland K, Grotzer MA, Frei K, Spertini O, Waterfield MD, Arcaro A
Anticancer Res. 2012 Aug;32(8):3015-27
Spertini C, Baïsse B, Spertini O
J Biol Chem. 2012 Mar 23;287(13):10693-702
Fernandez P, Solenthaler M, Spertini O, Quarroz S, Rovo A, Lovey PY, Leoncini L, Ruault-Jungblut S, D'Asaro M, Schaad O, Docquier M, Descombes P, Matthes T, Swiss Cytometry Society.
PLoS One. 2012;7(11):e49010
Novy J, Rosselet A, Spertini O, Lobrinus JA, Pabst T, Kuntzer T
Muscle Nerve. 2010 Feb;41(2):286-7
Védy D, Muehlematter D, Rausch T, Stalder M, Jotterand M, Spertini O
J Clin Oncol. 2010 Jan 20;28(3):e33-5
Baïsse B, Galisson F, Giraud S, Schapira M, Spertini O
BMC Evol Biol. 2007 Sep 14;7:166
Doepfner KT, Spertini O, Arcaro A
Leukemia. 2007 Sep;21(9):1921-30
Abbal C, Lambelet M, Bertaggia D, Gerbex C, Martinez M, Arcaro A, Schapira M, Spertini O
Blood. 2006 Nov 15;108(10):3352-9
Carrera E, Lobrinus JA, Spertini O, Gherardi RK, Kuntzer T
Neuromuscul Disord. 2006 Jul;16(7):468-71
Siegenthaler M, Spertini O
N Engl J Med. 2006 May 4;354(18):1936
Dunand M, Lobrinus JA, Spertini O, Kuntzer T
Muscle Nerve. 2005 May;31(5):646-51
Martinez M, Joffraud M, Giraud S, Baïsse B, Bernimoulin MP, Schapira M, Spertini O
J Biol Chem. 2005 Feb 18;280(7):5378-90
Silva AP, Cavadas C, Baïsse-Agushi B, Spertini O, Brunner HR, Grouzmann E
Regul Pept. 2003 Nov 15;116(1-3):71-9
Bernimoulin MP, Zeng XL, Abbal C, Giraud S, Martinez M, Michielin O, Schapira M, Spertini O
J Biol Chem. 2003 Jan 3;278(1):37-47