Development of new TBC diagnosis tools
Past project's Collaborators
Virginie ROZOT (to September 2013)
Alexandre HARARI (to June 2013)
Current plans are to follow patients under therapy and to investigate the panel of cytokine/chemokine profiles in different cell subsets. These observations may also help to predict the efficacy of the therapy or possibly, the presence of multi-resistant Mtb strains.
- Harari A, Rozot V, Enders FB, Perreau M, Stalder JM, Nicod LP, Cavassini M, Calandra T, Blanchet CL, Jaton K, Faouzi M, Day CL, Hanekom WA, Bart PA, Pantaleo G. Dominant TNF-+ Mycobacterium tuberculosis-specific CD4+ T cell responses discriminate between latent infection and active disease. Nat. Med. 2011, 17:372-376. PubMed