Pharmacokinetic-dynamic and population modeling
Our research on "PK-PD modeling" consists in:
- detailed description and analysis of the effects of drugs tested, with regards to the time and to their concentrations in the body;
- identification of sources of variability of these effects;
- development of strategies for the individualization of dosage based on the measurement of plasma -or even intracellular- levels.
The therapeutic areas we are interested in mainly encompass:
- HIV protease inhibitors;
- anticancer drugs;
- angiotensin II receptor antagonists;
- antibiotics.