Creating a spatially-resolved omics reference database in oncology

MOSAIC is a joint project between Owkin, an AI biotech company, and a consortium of academic institutions. The goal of this collaborative initiative is to build one of the largest spatial omics datasets ever, by studying thousands of tumor samples from different types of cancer.

Using advanced spatial and single-cell technologies, MOSAIC dataset enables the development of AI models to discover new drug targets, improve predictions about patient response to treatments, and support more personalized cancer care.

To achieve this, MOSAIC integrates six data modalities to create a molecular and spatial atlas of cancer. Notably, for spatial transcriptomics, we analyze thousands of formalin-fixed paraffin-embedded tumor samples using the Visium spatial platform, a high-throughput technology selected as the platform of choice in our benchmarking study.

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