IICT Calls

IICT Calls

On 27 June 2025, the SNSF published a news about six new clinical trials funded by the Investigator Initiated Clinical Trials (IICT) programme, in which the SCTO network of CTUs are largely involved.

We are delighted to announce a new funded project obtained by a main applicant from Lausanne University Hospital:

2024 call : Repurposing of empagliflozin for paediatric heart failure: a pharmacometric-informed, seamless, double-blind, randomized clinical trial among children with heart failure (REPhART).
Main applicants: Dr Sebastiano Lava & Dr Stefano Di Bernardo, Université de Lausanne – LA, approved amount: 3'209’981 CHF

Previous granted SNSF IICT call projects obtained by applicants from the University of Lausanne, with the involvement of the CTU Lausanne:

• 2023 call : PREcision ScrEeniNg for ColoRectal Cancer: a randomized non-inferiority Trial (PRESENT CRC).Main applicants: Kevin Selby, Marie-Anne Durand, Viviane Hess, Université de Lausanne – LA, approved amount: 2'332'324 CHF (involvement of the Research Support Sector, Unisanté)
• 2022 call : Effect of pulsatile GnRH therapy on cognition in Down syndrome: a randomized placebo controlled trial (Pulse-UP). Main applicant: Prof. Nelly Pitteloud, Université de Lausanne – LA, approved amount : 1'544'424 CHF
• 2021 call : Neurorehabilitation of Cognitive Deficits in Multiple Sclerosis Using an Adaptive Cognitive Exergame. Main applicant: Prof. Arseny Sokolov, Université de Lausanne – LA, approved amount: 1'954’229 CHF
• 2020 call : Procalcitonin and lung ultrasonography based antibiotherapy in patients with lower respiratory tract infection in Swiss emergency departments: stepped-wedge cluster-randomized trial. Main applicant: Dr. Noémie Boillat Blanco, Université de Lausanne – LA, approved amount: 2'868’314 CHF
• 2019 call : Fecal microbiota transplantation versus vancomycin or fidaxomicin in Clostridioides difficile infection first recurrence (Fender) An interventional, pragmatic, prospective, randomized, controlled trial. Main applicant: Prof. Benoit Guery, Université de Lausanne – LA, approved amount: 1'963’647 CHF
• 2017 call : Using Genetic Risk Factors to Stratify Antifungal Prophylaxis in Patients with Acute Myeloid Leukemia. Main applicant: Prof. Pierre-Yves Bochud, Université de Lausanne – LA, approved amount: 2'205’222 CHF
• 2016 call : Reducing the Burden of Influenza after Solid-Organ Transplantation: the STOP-FLU trial [Swiss Trial in Solid Organ Transplantation on Prevention of influenza]. Main applicant: Prof. Oriol Manuel, Université de Lausanne – LA, approved amount: 1'651'666 CHF

To get more information on the yearly IICT calls, see the SNSF Grant search webpage.