Understanding cardiac metabolism & energy production

Hyperpolarized 13C-CMR technique

This technique can produce up to 10’000-times higher signal than conventional MRI.

We established this technique (in collaboration with Prof. A. Comment CIBM-EPFL) to measure non-invasively glycolysis, Krebs-cycle activity, and beta-oxidation in the ischemia/reperfusion model of the rat (SNF grant, PI. J. Schwitter).

An extension of the SNF grant allows for future research applications to explore the myocardial metabolism in ischemia/reperfusion, heart failure, cardiomyopathies, and to assess novel treatment strategies in these diseases.

Publications

A total of 73 articles were published as a result of the CRMC research activity since its foundation in 2009.

All publications

Contacts

Pr Juerg Schwitter
MD, FESC
Director CMR Center
CHUV
Rue du Bugnon 46
1011 Lausanne
Tél. +41 21 314 0010
Fax +41 21 314 0013
 Dernière mise à jour le 30/05/2018 à 15:06