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Publications spécialisées
Sorafenib plus selective internal radiotherapy with (90)Y resin microspheres for the treatment of uveal melanoma with liver metastasis: a phase I trial.
Berthod G, Cisarovsky C, Petrova T, Decosterd LA, Choong E, Celestini D, Cuendet MA, Boughdad S, Prior JO, Meuwly JY, Figg WD, Michielin O, Leyvraz S
Br J Cancer. 2026 Feb;134(4):589-597
Population Pharmacokinetics of Propofol in Critically Ill Patients with and Without Extracorporeal Membrane Oxygenation.
Bertin S, Haefliger D, Mercier T, Decosterd LA, Giraud R, Assouline B, Schneider A, Buclin T, Guidi M, Livio F
Clin Pharmacokinet. 2026 Feb;65(2):229-240
Therapeutic Drug Monitoring and Point-of-Care Technologies: Opportunities and Current Challenges.
Carrara S, Widmer N, Rodino F, Du L, Briki M, Decosterd LA, Marzolini C, Buclin T, Thoma Y, Guidi M
Ther Drug Monit. 2026 Feb 1;48(1):42-53
Polypharmacy in HIV: Rethinking what counts and why it matters.
Sukumaran L, Winston A, Marzolini C, Khoo S, Boffito M, Naous N, Sabin CA
HIV Med. 2026 Feb;27(2):186-199
Screening for antibiotic residues among adults with respiratory infections in primary care in Switzerland: evaluating over-the-counter use and environmental exposure.
Wäfler N, Knüsli J, Lhopitallier L, Senn N, Marzolini C, Boillat-Blanco N
Clin Microbiol Infect. 2026 Jan;32(1):196-198
The Feasibility and Quality of the European Prescribing Exam: An International Multicenter Pilot Study Among 3109 Medical Students From 16 Medical Schools.
Donker EM, Piët JD, Brinkman DJ, Richir MC, Papaioannidou P, Likic R, Sanz EJ, Christiaens T, Costa JN, De Ponti F, Böttiger Y, Kramers C, van Agtmael MA, Tichelaar J, Erasmus+ consortium EuroPE+ and the EACPT Education Working Group
Clin Pharmacol Ther. 2026 Jan;119(1):190-197
CFTR during pregnancy and adverse drug reactions: A pharmacovigilance disproportionality analysis in VigiBase.
Abolhassani N, Dao K, Noseda R, Bedussi F, Ceschi A, Panchaud A, Winterfeld U
J Cyst Fibros. 2026 Jan;25(1):21-27
Major revision version 13.0 of the European AIDS Clinical Society guidelines 2025.
Ambrosioni J, Levi LI, Alagaratnam J, Sempere A, Mastrangelo A, Paioni P, Mussini C, Marzolini C, Nielsen SD, Béguelin C, Welch S, Koval A, Mendao L, Bamford A, Calmy A, Guaraldi G, Oprea C, Martínez E, Rockstroh JK, EACS Governing Board
HIV Med. 2026 Jan;27(1):18-32
Levetiracetam-induced rhabdomyolysis: a rare adverse effect in a patient with status epilepticus.
Crausaz L, Baumgartner T, Haefliger D, Rossetti AO
Neurol Sci. 2025 Dec 27;47(1):54
Piperacillin dosing in pediatric patients and augmented renal clearance: are current guidelines sufficient to achieve therapeutic concentration coverage?
Ravix A, Di Paolo ER, Dao K, Perez MH, Crisinel PA, Buclin T, André P, Marzolini C, Csajka C, Guidi M
J Antimicrob Chemother. 2025 Dec 2;80(12):3419-3430
Janus Kinase Inhibitors During Pregnancy and Adverse Drug Reactions: A Pharmacovigilance Disproportionality Analysis in VigiBase.
Abolhassani N, Noseda R, Dao K, Girardin FR, Bedussi F, Ceschi A, Panchaud A, Winterfeld U
Clin Transl Sci. 2025 Dec;18(12):e70429
Weight loss following gastric bypass increases aldosterone reactivity to orthostatic stress in patients with obesity.
Zahnd J, Vakilzadeh N, Schwotzer N, Hendriks-Balk M, Mantziari S, Sauser J, Maillard M, Grouzmann E, Favre L, Wuerzner G
Blood Press. 2025 Dec;34(1):2555452
Effects of Extracorporeal Membrane Oxygenation Circuits on Drug Sequestration: A Review of Ex Vivo Experiments.
Bertin S, Haefliger D, Schneider AG, Giraud R, Perez MH, Bechtold X, Di Paolo ER, Rothuizen LE, Buclin T, Livio F
J Clin Med. 2025 Nov 13;14(22)
International Collaboration to Develop and Harmonize Drug Interaction Guidance for Nirmatrelvir/Ritonavir During COVID-19: Lessons Learned for Future Pandemic Preparedness.
Kuriakose S, Tseng A, Boyd S, Gibbons S, Chiong J, Marra F, Boyle A, Senneker T, George J, Lund C, Belperio P, Crew P, Eschenauer G, Scarsi KK, Khoo SH, Pau A, Marzolini C, LiON-PK collaboration
Clin Infect Dis. 2025 Nov 3
Percutaneous Radiofrequency Ablation After Incomplete Adrenalectomy in a Lateralized Case of Primary Aldosteronism.
Rigon PA, Villard N, Abid KA, Zingg T, Eimer S, Wuerzner G
JCEM Case Rep. 2025 Dec;3(12):luaf251
Communicating medication risks in pregnancy: Towards shared decision making.
Winterfeld U, Hodson K, Berlin M, Marin B, Ceulemans M, Weber-Schoendorfer C, Girardin FR, Baud D, Schaad B, Panchaud A
Front Drug Saf Regul. 2025;5:1712216
Leukocyte count and new-onset diabetes mellitus in people with HIV: A longitudinal study.
Meyer SC, Klein Z, Schoepf IC, Thorball CW, Labarile M, Kootstra NA, Reiss P, Ryom L, Braun DL, Thurnheer MC, Marzolini C, Kahlert CR, Bernasconi E, Cavassini M, Marinosci A, Fellay J, Günthard HF, Kouyos RD, Ledergerber B, Tarr PE, Swiss HIV Cohort Study
HIV Med. 2025 Oct;26(10):1585-1599
Therapeutic drug monitoring of Janus kinase inhibitors for precision dosing: where do we stand ?
Tachet J, Marzolini C, Decosterd LA, Guidi M, Girardin FR
Expert Rev Clin Pharmacol. 2025 Oct;18(10):1-17
Therapeutic Drug Monitoring for Precision Dosing of Janus Kinase Inhibitors: Protocol for a Prospective Observational Study.
Tachet J, Decosterd LA, Guidi M, Girardin FR
JMIR Res Protoc. 2025 Sep 9;14:e70312
A Scoping Review of Human Teratogens and Their Impact on the Developing Brain: A Contribution From the ConcePTION Project.
Bluett-Duncan M, Adams J, Berkovitch M, Berlin M, Cahoon A, Clayton-Smith J, Jackson C, Khanom S, Mølgaard-Nielsen D, Richardson JL, Simms V, Stellfeld M, Winterfeld U, Yates LM, Bromley RL
Birth Defects Res. 2025 Sep;117(9):e2497
Untargeted Metabolite Profile Associations with Body Mass Index, Waist-Hip Ratio, and Antiretroviral Therapy in >1300 People with HIV: the Swiss HIV Cohort Study.
Labarile M, Schoepf IC, Pasin C, Oumelloul MA, Thorball CW, Riebensahm C, Surial B, Wandeler G, Braun DL, Marzolini C, Kahlert CR, Bernasconi E, Cavassini M, Calmy A, Nemeth J, Bally L, Reiss P, Telenti A, Ledergerber B, Günthard HF, Fellay J, Zamboni N, Kouyos RD, Tarr PE, Swiss HIV Cohort Study
J Infect Dis. 2025 Aug 27
A comparison between venous blood sampling and capillary volumetric absorptive microsampling for antibiotics levels monitoring in individuals with and without periodontal disease.
Lazaridi I, Choong E, Mercier T, Decosterd LA, Giannopoulou C, Zekeridou A
Clin Oral Investig. 2025 Aug 23;29(9):420
Is Therapeutic Drug Monitoring of Long-Acting Cabotegravir and Rilpivirine of Clinical Utility?
Marzolini C
Clin Infect Dis. 2025 Aug 18
Population pharmacokinetics of bictegravir in real-world people with HIV.
Ekobena P, Briki M, Dao K, Marzolini C, Andre P, Buclin T, Cavassini M, Guidi M, Thoueille P, Swiss HIV Cohort Study
J Antimicrob Chemother. 2025 Aug 13
Pragmatic and contextualized methods selection for safety assessment of infant systemic exposure through human milk: the Milk4baby decision tree approach - a contribution from the concePTION project.
Monfort A, Macente J, Van Neste M, Huang MC, Nauwelaerts N, Abza GB, Winterfeld U, Smits A, Allegaert K, Annaert P, Guidi M, Panchaud A
Front Pharmacol. 2025;16:1602018
Rifampicin Exposure in Tuberculosis Patients with Comorbidities in Sub-Saharan Africa: Prioritising Populations for Treatment-A Systematic Review and Meta-analysis.
Said B, Pétermann Y, Howlett P, Guidi M, Thoma Y, Kajogoo VD, Sariko M, Heysell SK, Alffenaar JW, Mpolya E, Mpagama S
Clin Pharmacokinet. 2025 Aug;64(8):1149-1163
Is Nonsustained Viral Suppression With Long-Acting Cabotegravir and Rilpivirine Really Independent of Drug Levels?
Thoueille P, Marzolini C, Guidi M, Cavassini M, Decosterd LA
Clin Infect Dis. 2025 Aug 1;81(1):e4-e5
Pharmacokinetics of levosimendan in critically Ill children on extracorporeal membrane oxygenation: a prospective observational study.
Bertin S, Haefliger D, Perez MH, Guidi M, Decosterd LA, Chanez V, Di Paolo ER, Buclin T, Livio F
Front Pediatr. 2025;13:1542417
Is the salivary concentration of lamotrigine and levetiracetam associated with clinical outcome?
Vassallo P, Choong E, Aícua-Rapún I, Stampfli C, André P, Rossetti AO, Buclin T, Decosterd LA, Novy J
Epilepsy Behav. 2025 Jul 21;171:110595
Numerical Verification of Tucuxi, a Promising Bayesian Adaptation Tool for Model-Informed Precision Dosing.
Ravix A, Cathignol AE, Buclin T, Csajka C, Guidi M, Thoma Y
CPT Pharmacometrics Syst Pharmacol. 2025 Jul 17
Influence of CYP2D6 Genotypes and Phenotypes on the Plasma Levels and Clinical Response to Aripiprazole.
Gras C, Piras M, Ranjbar S, Grosu C, Girardin FR, Vandenberghe F, Ansermot N, Grandjean C, Kaiser S, Gamma F, Plessen KJ, von Gunten A, Conus P, Crettol S, Eap CB
Schizophr Bull. 2025 Jul 14
A New Prognostic Score Based on Cell-Mediated Immunity for Cytomegalovirus Infection After Transplantation.
Kervella D, Casanova-Ferrer F, Kotton CN, Donadeu L, Kumar D, Pineda S, Crespo E, Meneghini M, González-Costelo J, García-Romero E, Lladó L, Cachero A, Melilli E, Torres IB, Martínez-Lacalle A, Castañeda Z, Martinez-Gallo M, Len O, Los-Arcos I, Trilla-Herrera E, Miret E, Giral M, Brouard S, Girardin FR, Villard J, Budde K, Lefaucheur C, Loupy A, Moreso F, Bestard O
Kidney Int Rep. 2025 Sep;10(9):3044-3057
Quality of Clinical Information in Pregnancy Pharmacovigilance Data Sources-A Contribution of the ConcePTION Project.
van Rijt-Weetink YRJ, van Gendt J, Egberts TCG, van Hunsel FPAM, Lewis DJ, Yates LM, Winterfeld U, van Puijenbroek EP
Pharmacoepidemiol Drug Saf. 2025 Jul;34(7):e70182
Mycobacterium tuberculosis Infection and Acute or Subclinical Coronary Artery Disease: the Swiss HIV Cohort Study.
Hilfiker A, Schoepf IC, Avery EF, Ledergerber B, Colin-Benoit E, Riebensahm C, Marzolini C, Kahlert CR, Bernasconi E, Cavassini M, Marinosci A, Günthard HF, Kouyos R, Nemeth J, Tarr PE, Swiss HIV Cohort Study
J Acquir Immune Defic Syndr. 2025 Jun 20
Types of Myocardial Infarction in People With HIV in Switzerland.
Kleynhans JN, Cobo NN, Avery EF, Buechel RR, Thorball CW, Schoepf IC, Coscia T, Braun DL, Colin-Benoit E, Marzolini C, Kahlert CR, Bernasconi E, Cavassini M, Marinosci A, Kusejko K, Fellay J, Günthard HF, Ledergerber B, Tarr PE, Swiss HIV Cohort Study
Open Forum Infect Dis. 2025 Jul;12(7):ofaf357
Type I interferon autoantibody footprints reveal neutralizing mechanisms and allow inhibitory decoy design.
Groen K, Kuratli R, Enkelmann J, Fernbach S, Wendel-Garcia PD, Staiger WI, Lejeune M, Sauras-Colón E, Roche-Campo F, Filippidis P, Rauch A, Swiss HIV Cohort Study, Trkola A, Günthard HF, Kouyos RD, Brugger SD, Hale BG
J Exp Med. 2025 Jun 2;222(6)
Multidisciplinary consensus on prevention, screening and monitoring of clozapine-associated myocarditis and clozapine rechallenge after myocarditis.
Wagner E, Korman N, Solmi M, Mortazavi M, Aminifarsani Z, Dubrovin Leão D, Burrage MK, Siskind D, McMahon L, Howes OD, Correll CU, CAM Expert Group, Hasan A
Br J Psychiatry. 2025 Jun 2:1-9
Dose Evaluation and Optimization of Amoxicillin in Children Treated for Lyme Disease.
Ravix A, Gotta V, Pfister M, Berger C, Glauser A, Paioni P, Csajka C, Guidi M
J Clin Pharmacol. 2025 Jun;65(6):742-750
Delphi Method Consensus on Statistical Analysis and Reporting Recommendations for Single-Arm Pregnancy Medication Safety Studies Investigating Pregnancy, Birth and Neonatal Health Outcomes: A Contribution from IMI-ConcePTION.
Richardson JL, Moore A, Stellfeld M, Geissbühler Y, Winterfeld U, Favre G, Chambers C, Beck E, Onken M, Dathe K, Ceulemans M, Diav-Citrin O, Shechtman S, Oliver AM, Hodson KK, Shiller DD, Alexe A, van Puijenbroek EP, Lewis DJ, Yates LM
Drug Saf. 2025 Jun;48(6):643-654
[Glucagon-like peptide 1 agonists : the fourth pillar of nephroprotection in type 2 diabetes].
Lamine F, Chtioui H, Zanchi A
Rev Med Suisse. 2025 May 28;21(920):1117-1120
Roux-en-Y gastric bypass in a patient with Wilson's disease and obesity.
Balaphas A, Sempoux C, Samer CF, Chtioui H, Saadi A, Collaborators
J Hepatol. 2025 May;82(5):e222-e223
Statin use in HIV: European AIDS Clinical Society guidance for the primary prevention of cardiovascular disease.
Alagaratnam J, van Bremen K, Behrens GMN, Boccara F, Cinque P, Gisslén M, Guaraldi G, Konopnicki D, Kowalska JD, Mallon PWG, Marzolini C, Mendão L, Miró JM, Negredo E, Reiss P, Ryom L, van der Valk M, Winston A, Nielsen SD, Martínez E
Lancet HIV. 2025 May;12(5):e382-e392
A Liquid Chromatography-Tandem Mass Spectrometry Method for the Quantification of Cystic Fibrosis Drugs (Caftors) in Plasma and Its Application for Therapeutic Monitoring.
D'Atri V, Corrado F, Versace F, Saldanha SA, Mercier T, Guidi M, Thoueille P, Blanchon S, Koutsokera A, Vogeser M, Marzolini C, Girardin F, Mitropoulou G, Balmpouzis Z, Rochat I, Sauty A, Decosterd LA, Choong E
Molecules. 2025 Apr 22;30(9)
Risk of adverse obstetrical and neonatal outcomes in women consuming recreational drugs during pregnancy.
Kandhasamy S, Lepigeon K, Baggio S, Céline R, Ceulemans M, Winterfeld U, Jenkinson SP, Francini K, Maisonneuve E, Panchaud A
BMC Pregnancy Childbirth. 2025 Apr 16;25(1):456
Initiating or Resuming Cancer Treatment After Ischemic Stroke and Clinical Outcomes.
Costamagna G, Hottinger AF, Strambo D, Livio F, Navi BB, Michel P
Neurology. 2025 Apr 8;104(7):e213458
Sustained viral suppression with once daily dolutegravir-containing regimen in presence of the strong inducer carbamazepine.
Pallanza M, Thoueille P, Briki M, Alves Saldanha S, Cavassini M, Marzolini C
Antivir Ther. 2025 Apr;30(2):13596535251335080
Highly sensitive ultra-high-performance liquid chromatography coupled with tandem mass spectrometry method for the multiplex analysis of levosimendan and its metabolites OR-1855 and OR-1896 in human plasma.
Bertin S, Versace F, Mercier T, Murisier A, Sauvain G, Haefliger D, Girardin FR, Perez MH, Giraud R, Schneider A, Buclin T, Decosterd LA, Choong E, Livio F
J Pharm Biomed Anal. 2025 Mar 15;255:116612
Individualization of piperacillin dosage based on therapeutic drug monitoring with or without model-informed precision dosing: a scenario analysis.
Haefliger D, Mina L, Guidi M, Marzolini C, Thoueille P, Rothuizen LE, Thoma Y, Decosterd LA, Guery B, Girardin FR, Buclin T
J Antimicrob Chemother. 2025 Mar 3;80(3):840-847
N-of-1 tests in general practice: pharmacological considerations.
Diezi L, Anastasi M, Brutus L, Buclin T
Br J Gen Pract. 2025 Mar;75(752):132-135
Microvascular Inflammation of Kidney Allografts and Clinical Outcomes.
Sablik M, Sannier A, Raynaud M, Goutaudier V, Divard G, Astor BC, Weng P, Smith J, Garro R, Warady BA, Zahr RS, Twombley K, Dharnidharka VR, Dandamudi RS, Fila M, Huang E, Sellier-Leclerc AL, Tönshoff B, Rabant M, Verine J, Del Bello A, Berney T, Boyer O, Catar RA, Danger R, Giral M, Yoo D, Girardin FR, Alsadi A, Gourraud PA, Morelon E, Le Quintrec M, Try M, Villard J, Zhong W, Bestard O, Budde K, Chauveau B, Couzi L, Brouard S, Hogan J, Legendre C, Anglicheau D, Aubert O, Kamar N, Lefaucheur C, Loupy A
N Engl J Med. 2025 Feb 20;392(8):763-776
Population-Based Prevalence of Antibiotic Residuals in Low, Moderate and High Malaria Endemicity Areas in Tanzania.
Lotto T, Gallay J, Zuakulu M, Ternon B, Decosterd LA, Kulinkina AV, Genton B
Antibiotics (Basel). 2025 Feb 13;14(2)
Enhancing perinatal health patient information through ChatGPT - An accuracy study.
de Vries PLM, Baud D, Baggio S, Ceulemans M, Favre G, Gerbier E, Legardeur H, Maisonneuve E, Pena-Reyes C, Pomar L, Winterfeld U, Panchaud A
PEC Innov. 2025 Jun;6:100381
Pénurie de médicaments : « Les actions concrètes restent relativement limitées ».
Buclin T
Rev Med Suisse. 2025 Feb 5;21(904):249-250
Neurodevelopmental outcomes of infants after in utero exposure to SARS-CoV-2 or mRNA-COVID-19 vaccine compared with unexposed infants: a COVI-PREG prospective cohort study.
Favre G, Bromley RL, Bluett-Duncan M, Maisonneuve E, Pomar L, Daire C, Radan AP, Raio L, Surbek D, Blume C, Kalimeris S, Madec Y, Schneider J, Bickle Graz M, Winterfeld U, Panchaud A, Baud D
Clin Microbiol Infect. 2025 Feb;31(2):266-273
Improving Understanding of Fexofenadine Pharmacokinetics to Assess Pgp Phenotypic Activity in Older Adult Patients Using Population Pharmacokinetic Modeling.
Gaspar F, Jacost-Descombes C, Gosselin P, Reny JL, Guidi M, Csajka C, Samer C, Daali Y, Terrier J
Clin Pharmacokinet. 2025 Feb;64(2):275-283
Clinical value of saliva therapeutic drug monitoring of newer antiseizure medications.
Choong E, Vassallo P, Aícua-Rapún I, Stampfli C, André P, Rossetti AO, Buclin T, Novy J, Decosterd LA
Seizure. 2025 Feb;125:106-112
Antibacterial and antifungal drug concentrations in intra-abdominal abscesses: a prospective clinical study.
Cancela Costa A, Grass F, Andres Cano I, Desgranges F, Delabays C, Kritikos A, Glampedakis E, Buclin T, Duran R, Guery B, Pagani J-L, Uldry E, Decosterd LA, Lamoth F
Antimicrob Agents Chemother. 2025 Jan 31;69(1):e0117824
[Teratovigilance. Antiepileptics during pregnancy and paternal use].
Dao K, Diezi L, Haefliger D, Novy J, Girardin FR, Winterfeld U
Rev Med Suisse. 2025 Jan 15;21(900-1):77-80
Acute aseptic meningitis temporally associated with trimethoprim and sulfamethoxazole: Systematic review.
Bernasconi GF, Milani GP, De Felice ELT, Laurence C, Faré PB, Terziroli Beretta-Piccoli B, Bianchetti MG, Lava SAG
Br J Clin Pharmacol. 2025 Jan;91(1):236-243
Population pharmacokinetic modelling of cetirizine concentrations in human breast milk-A contribution from the ConcePTION project.
Melander E, Nielsen EI, Lindqvist A, Hovd M, Gandia P, Panchaud A, Guidi M, Annaert P, Baranczewski P, Spigset O, Nordeng H
Basic Clin Pharmacol Toxicol. 2025 Jan;136(1):e14100
Removal of Meropenem and Piperacillin during Experimental Hemoadsorption with the HA380 Cartridge.
Furukawa T, Lankadeva Y, Baldwin I, Ow PCC, Hood S, Schneider A, Decosterd LA, May CN, Bellomo R
Blood Purif. 2025;54(2):102-110
Removal of Psychotropic Drugs by Hemoadsorption with the HA380 Cartridge.
Furukawa T, Lankadeva YR, Baldwin IC, Ow PCC, Hood S, Eap CB, Schneider A, Decosterd LA, Bellomo R
Blood Purif. 2025;54(12):715-722
Removal of Ticagrelor by Hemoadsorption with the HA380 Cartridge.
Furukawa T, Lankadeva YR, Baldwin IC, Ow PCC, Hood S, Daali Y, Schneider A, Decosterd LA, May CN, Bellomo R
Blood Purif. 2025;54(4-5):226-230
Drug-drug interactions potential with the HIV-1 capsid inhibitor lenacapavir.
Marzolini C, Gibbons S, Seddon D, Khoo S
Expert Opin Drug Metab Toxicol. 2025 Jan-Feb;21(2):161-172
Importance of Sex-Dependent Differences for Dosing Selection and Optimization of Chemotherapeutic Drugs.
Seydoux C, Briki M, Wagner AD, Choong E, Guidi M, Carrara S, Thoma Y, Livio F, Girardin FR, Marzolini C, Buclin T, Decosterd LA
Chemotherapy. 2025;70(2):92-101
Impact of adolescents' binge drinking on blood chemistry.
Pistritto E, Schera FMF, Vassilopoulou E, Corsello A, Alberti I, Lava SAG, Betti C, Bianchetti MG, Agostoni C, Camozzi P, Milani GP
Eur J Pediatr. 2024 Dec 12;184(1):77
Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells.
Sáez-Cirión A, Mamez AC, Avettand-Fenoel V, Nabergoj M, Passaes C, Thoueille P, Decosterd L, Hentzien M, Perdomo-Celis F, Salgado M, Nijhuis M, Mélard A, Gardiennet E, Lorin V, Monceaux V, Chapel A, Gourvès M, Lechartier M, Mouquet H, Wensing A, Martinez-Picado J, Yerly S, Rougemont M, Calmy A
Nat Med. 2024 Dec;30(12):3544-3554
Population pharmacokinetics of rilpivirine following oral administration and long-acting intramuscular injection in real-world people with HIV.
Thoueille P, Saldanha SA, Schaller F, Choong E, Veuve F, Munting A, Cavassini M, Braun D, Günthard HF, Duran Ramirez JJ, Surial B, Furrer H, Rauch A, Ustero P, Calmy A, Stöckle M, Di Benedetto C, Bernasconi E, Schmid P, Marzolini C, Girardin FR, Buclin T, Decosterd LA, Guidi M
Front Pharmacol. 2024;15:1437400
State of the art of real-life concentration monitoring of rifampicin and its implementation contextualized in resource-limited settings: the Tanzanian case.
Petermann YJ, Said B, Cathignol AE, Sariko ML, Thoma Y, Mpagama SG, Csajka C, Guidi M
JAC Antimicrob Resist. 2024 Dec;6(6):dlae182
Effects of maternal modafinil treatment on fetal development and neonatal growth parameters - a multicenter case series of the European Network of Teratology Information Services (ENTIS).
Onken M, Lohse L, Coulm B, Beghin D, Richardson JL, Bermejo-Sánchez E, Aguilera C, Bosch M, Cassina M, Chouchana L, De Santis M, Duman MK, Gören MZ, Johnson D, Bera APJ, Kaplan YC, Kennedy D, Kwok S, Lacroix I, Lepelley M, Pistelli A, Schaefer C, Te Winkel B, Uysal N, Winterfeld U, Yakuwa N, Diav-Citrin O, Vial T, Dathe K
Acta Psychiatr Scand. 2024 Nov;150(5):372-384
A population pharmacokinetic model for sertraline in women during the perinatal period-A contribution from the ConcePTION project.
Monfort A, Cardoso E, Eap CB, Ansermot N, Crettol S, Fischer Fumeaux CJ, Graz MB, Harari MM, Weisskopf E, Gandia P, Allegaert K, Annaert P, Nordeng H, Hascoët JM, Claris O, Epiney M, Ferreira E, Leclair G, Csajka C, Panchaud A, Guidi M, collaborators of the SSRI Breast Milk study
Br J Clin Pharmacol. 2024 Nov;90(11):2849-2860
Vancomycin Dosing Strategy for the Treatment of Peritonitis in a Child on Automated Peritoneal Dialysis: A First Pediatric Case Report.
Haefliger D, Chehade H, Livio F, Rodrigues-Veiga V, Diezi L, Marzolini C
Semin Dial. 2024 Nov-Oct;37(6):461-465
Toward a Clinical Decision Support System for Monitoring Therapeutic Antituberculosis Medical Drugs in Tanzania (Project TuberXpert): Protocol for an Algorithm' Development and Implementation.
Thoma Y, Cathignol AE, Pétermann YJ, Sariko ML, Said B, Csajka C, Guidi M, Mpagama SG
JMIR Res Protoc. 2024 Oct 21;13:e58720
Efficacy and Safety of Dolutegravir Plus Emtricitabine vs Combined Antiretroviral Therapy for the Maintenance of HIV Suppression: Results Through Week 144 of the SIMPL'HIV Trial.
Marinosci A, Sculier D, Wandeler G, Yerly S, Stoeckle M, Bernasconi E, Braun DL, Vernazza P, Cavassini M, Decosterd L, Günthard HF, Schmid P, Limacher A, Branca M, Calmy A, Swiss HIV Cohort Study
Open Forum Infect Dis. 2024 Nov;11(11):ofae618
Weight, Anthropometric and Metabolic Changes After Discontinuing Antiretroviral Therapy Containing Tenofovir Alafenamide in People With HIV.
Damas J, Munting A, Fellay J, Haerry D, Marzolini C, Tarr PE, Steffen A, Braun DL, Stoeckle M, Bernasconi E, Nawej Tshikung O, Fux CA, Darling KEA, Béguelin C, Wandeler G, Cavassini M, Surial B, Swiss HIV Cohort Study (SHCS)
Clin Infect Dis. 2024 Oct 15;79(4):990-998
Ideal Time to Conduct a Pharmacokinetic Investigation After Delivery to Fully Capture the Effect of Pregnancy on Drug Exposure.
Berton M, Stader F, Bettonte S, Battegay M, Marzolini C
Open Forum Infect Dis. 2024 Oct;11(10):ofae585
Epstein-Barr virus as promoter of Lemierre syndrome: systematic literature review.
Delcò AA, Montorfani SMMA, Gualtieri R, Lava SAG, Milani GP, Bianchetti MG, Bronz G, Faré PB, Kottanattu L
Eur Arch Otorhinolaryngol. 2024 Oct;281(10):5497-5502
Novel Patient-Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced Palatability, Controlled Absorption, and Less Variability: High Potential for Pediatric Use.
Dao K, Buettcher M, Golhen K, Kost J, Schittny A, Duthaler U, Atkinson A, Haefliger D, Guidi M, Bardinet C, Chtioui H, Boulekbache A, Buclin T, Huwyler J, Pfister M, Rothuizen LE
J Clin Pharmacol. 2024 Oct;64(10):1295-1303
Transient secondary pseudo-hypoaldosteronism in infants with urinary tract infections: systematic literature review.
Betti C, Lavagno C, Bianchetti MG, Kottanattu L, Lava SAG, Schera F, Lacalamita MC, Milani GP
Eur J Pediatr. 2024 Oct;183(10):4205-4214
Drug-Related Pyroglutamic Acidosis: Systematic Literature Review.
Scafetta T, Kovacs O, Milani GP, Bronz G, Lava SAG, Betti C, Vanoni F, Bianchetti MG, Faré PB, Camozzi P
J Clin Med. 2024 Sep 27;13(19)
Gender Disparities in Statin Prescriptions in People With HIV With Low/Moderate to High Cardiovascular Risk.
Abela IA, Chammartin F, Amstutz A, Surial B, Ballif M, Marzolini C, Aebi-Popp K, Notter J, Segeral O, Stoeckle M, Cavassini M, Bernasconi E, Günthard HF, Kouyos RD, Pasin C, Swiss HIV Cohort Study
Open Forum Infect Dis. 2024 Sep;11(9):ofae502
Pharmacometrics to Evaluate Dosing of the Patient-Friendly Ivermectin CHILD-IVITAB in Children ≥ 15 kg and <15 kg.
Golhen K, Buettcher M, Huwyler J, van den Anker J, Gotta V, Dao K, Rothuizen LE, Kobylinski K, Pfister M
Pharmaceutics. 2024 Sep 7;16(9)
Prevalence of actionable pharmacogenetic variants and high-risk drug prescriptions: A Swiss hospital-based cohort study.
Hodel F, De Min MB, Thorball CW, Redin C, Vollenweider P, Girardin F, Fellay J
Clin Transl Sci. 2024 Sep;17(9):e70009
Bridging the Evidence Gap: Sotrovimab Use in Pregnancy and the Need for Comprehensive Drug Safety Data.
Winterfeld U
Drug Saf. 2024 Sep;47(9):841-842
Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN).
Goutaudier V, Danger R, Catar RA, Racapé M, Philippe A, Elias M, Raynaud M, Aubert O, Bouton D, Girardin F, Vicaut É, Yaiche S, Demotes J, Heidecke H, Taupin JL, Randoux-Lebrun C, Zaidan M, Papuchon E, Le Mai H, Nguyen TV, Moreso F, Berney T, Villard J, Legendre C, Dragun D, Papalois V, Potena L, Giral M, Gourraud PA, Brouard S, Crespo E, Halleck F, Budde K, Bestard O, Loupy A, Lefaucheur C, EU-TRAIN Consortium
Kidney Int. 2024 Aug 27
Effect of Obesity on the Exposure of Long-acting Cabotegravir and Rilpivirine: A Modeling Study.
Bettonte S, Berton M, Stader F, Battegay M, Marzolini C
Clin Infect Dis. 2024 Aug 16;79(2):477-486
Prevalence and predictors of residual antibiotics in children's blood in community settings in Tanzania.
Lotto T, Renggli S, Kaale E, Masanja H, Ternon B, Décosterd LA, D'Acremont V, Genton B, Kulinkina AV
Clin Microbiol Infect. 2024 Aug;30(8):1042-1048
Exposures to non-therapeutic chemicals before, during and after pregnancy: data from the Swiss Teratogen Information Service (STIS).
Srikantha P, Winterfeld U, Girardin F, Panchaud A, Ochsenbein-Kölble N, Simões-Wüst AP
Swiss Med Wkly. 2024 Jul 16;154:3751
Antifungal drug penetration in soft tissue abscesses: a comparative analysis.
Cancela Costa A, Kritikos A, Glampedakis E, Da Silva Pereira Clara J, Schaller F, Mercier T, Strasser R, Balmpouzis Z, Koutsokera A, Manuel O, Buclin T, Decosterd LA, Lamoth F
J Antimicrob Chemother. 2024 Jul 1;79(7):1668-1672
Oritavancin use in patients with recurrent bone infections by methicillin-resistant Staphylococcus aureus with monitoring of concentrations.
Bongiovanni M, Thoueille P, Barda B, Mercier T, Marzolini C, Ramponi N, Choong E, Cantù M, Decosterd LA, Bernasconi E
Eur J Clin Microbiol Infect Dis. 2024 Jul;43(7):1503-1504
Neuropeptide Y and Derivates Are Not Ready for Prime Time in Prostate Cancer Early Detection.
Maurer J, Eugster PJ, Collins K, Vocat C, Oke J, Nicholson B, Rakauskas A, Grouzmann E, Valerio M
Eur Urol Open Sci. 2024 Aug;66:12-15
Quantification of endogenous Angiotensin 1-10, 1-9, 1-8, 1-7, and 1-5 in human plasma using micro-UHPLC-MS/MS: Outlining the importance of the pre-analytics for reliable results.
Maurer J, de Groot A, Martin L, Grouzmann E, Wuerzner G, Eugster PJ
J Pharm Biomed Anal. 2024 Jun 15;243:116101
Population Pharmacokinetics of Trametinib and Impact of Nonadherence on Drug Exposure in Oncology Patients as Part of the Optimizing Oral Targeted Anticancer Therapies Study.
Ravix A, Bandiera C, Cardoso E, Lata-Pedreira A, Chtioui H, Decosterd LA, Wagner AD, Schneider MP, Csajka C, Guidi M
Cancers (Basel). 2024 Jun 11;16(12)
Immunomodulation profile of the biosimilar trastuzumab MYL-1401O in a bioequivalence phase I study.
Audran R, Chtioui H, Thierry AC, Mayor CE, Vallotton L, Dao K, Rothuizen LE, Maghraoui A, Pennella EJ, Brunner-Ferber F, Buclin T, Spertini F
Sci Rep. 2024 Jun 4;14(1):12872
Population Pharmacokinetics of Cabotegravir Following Oral Administration and Long-Acting Intramuscular Injection in Real-World People with HIV.
Thoueille P, Saldanha SA, Schaller F, Choong E, Veuve F, Munting A, Cavassini M, Braun D, Günthard HF, Duran Ramirez JJ, Surial B, Furrer H, Rauch A, Ustero P, Calmy A, Stöckle M, Di Benedetto C, Bernasconi E, Schmid P, Marzolini C, Girardin FR, Buclin T, Decosterd LA, Guidi M, Swiss HIV Cohort Study
Clin Pharmacol Ther. 2024 Jun;115(6):1450-1459
Population Pharmacokinetics in Oncology and Its Clinical Applications.
Widmer N, Guidi M, Buclin T
Pharmaceutics. 2024 May 25;16(6)
Drug- and Toxin-Induced Opsoclonus - a Systematized Review, including a Case Report on Amantadine-Induced Opsoclonus in Multiple System Atrophy.
Cannilla H, Messe M, Girardin F, Borruat FX, Bally JF
Tremor Other Hyperkinet Mov (N Y). 2024;14:23
DeepARV: ensemble deep learning to predict drug-drug interaction of clinical relevance with antiretroviral therapy.
Pham T, Ghafoor M, Grañana-Castillo S, Marzolini C, Gibbons S, Khoo S, Chiong J, Wang D, Siccardi M
NPJ Syst Biol Appl. 2024 May 6;10(1):48
Development of a physiologically-based pharmacokinetic model to simulate the pharmacokinetics of intramuscular antiretroviral drugs.
Bettonte S, Berton M, Battegay M, Stader F, Marzolini C
CPT Pharmacometrics Syst Pharmacol. 2024 May;13(5):781-794
Isavuconazole for the Treatment of Fungal Infections: A Real-life Experience From the Fungal Infection Network of Switzerland (FUNGINOS).
Couchepin J, Reinhold I, Kronig I, Guidi M, Buclin T, Schreiber PW, Neofytos D, Lamoth F, Fungal Infection Network of Switzerland (FUNGINOS)
Open Forum Infect Dis. 2024 May;11(5):ofae223
Use of GLP1 receptor agonists in early pregnancy and reproductive safety: a multicentre, observational, prospective cohort study based on the databases of six Teratology Information Services.
Dao K, Shechtman S, Weber-Schoendorfer C, Diav-Citrin O, Murad RH, Berlin M, Hazan A, Richardson JL, Eleftheriou G, Rousson V, Diezi L, Haefliger D, Simões-Wüst AP, Addor MC, Baud D, Lamine F, Panchaud A, Buclin T, Girardin FR, Winterfeld U
BMJ Open. 2024 Apr 24;14(4):e083550
Costs and acceptability of simplified monitoring in HIV-suppressed patients switching to dual therapy: the SIMPL'HIV open-label, factorial randomised controlled trial.
Marinosci A, Sculier D, Wandeler G, Yerly S, Stoeckle M, Bernasconi E, Braun DL, Vernazza P, Cavassini M, Buzzi M, Metzner KJ, Decosterd L, Günthard HF, Schmid P, Limacher A, Branca M, Calmy A
Swiss Med Wkly. 2024 Apr 15;154:3762
Hypertension in a Patient With Polycystic Kidney Disease Complicated by Concomitant Pheochromocytoma.
Ameti A, Kopp PA, Pitteloud N, Wuerzner G, Grouzmann E, Matter M, Lamine F, Phan O
AACE Clin Case Rep. 2024 Jul-Aug;10(4):136-139
Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) methods for the therapeutic drug monitoring of cytotoxic anticancer drugs: An update.
Briki M, Murisier A, Guidi M, Seydoux C, Buclin T, Marzolini C, Girardin FR, Thoma Y, Carrara S, Choong E, Decosterd LA
J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Apr 1;1236:124039
Population pharmacokinetic analysis of doravirine in real-world people with HIV.
Thoueille P, Delarive L, Cavassini M, Buclin T, Decosterd LA, Marzolini C, Girardin FR, Guidi M, Swiss HIV Cohort Study
Br J Clin Pharmacol. 2024 Apr;90(4):1058-1065
Acute ischaemic stroke in active cancer versus non-cancer patients: stroke characteristics, mechanisms and clinical outcomes.
Costamagna G, Hottinger AF, Milionis H, Salerno A, Strambo D, Livio F, Navi BB, Michel P
Eur J Neurol. 2024 Apr;31(4):e16200
Drug Exposure of Long-Acting Cabotegravir and Rilpivirine in Older People With Human Immunodeficiency Virus: A Pharmacokinetic Modeling Study.
Bettonte S, Berton M, Stader F, Battegay M, Marzolini C
Open Forum Infect Dis. 2024 Apr;11(4):ofae171
Outcomes of Drug Interactions Between Antiretrovirals and Co-Medications, Including Over-the-Counter Drugs: A Real-World Study.
Ambrosioni J, Díaz NA, Marzolini C, Dragovic G, Imaz A, Calcagno A, Luque S, Curran A, Troya J, Tuset M, Khoo S, Burger D, Cortés CP, Naous N, Molto J
Infect Dis Ther. 2024 Mar;13(3):609-617
Improving Data Collection in Pregnancy Safety Studies: Towards Standardisation of Data Elements in Pregnancy Reports from Public and Private Partners, A Contribution from the ConcePTION Project.
Favre G, Richardson JL, Moore A, Geissbühler Y, Jehl V, Oliver A, Shechtman S, Diav-Citrin O, Berlin M, De Haan T, Baud D, Panchaud A, Mor A, Sabidó M, de Souza S, Chambers C, van Rijt-Weetink YRJ, van Puijenbroek EP, Yates LM, Girardin F, Stellfeld M, Winterfeld U
Drug Saf. 2024 Mar;47(3):227-236
Validation of a Novel Method to Assess the Clinical Quality of Information in Pregnancy-Related Pharmacovigilance Case Reports: A ConcePTION Project.
van Rijt-Weetink YRJ, Egberts TCG, van Hunsel FPAM, Lewis DJ, Yates LM, Winterfeld U, van Puijenbroek EP
Drug Saf. 2024 Mar;47(3):261-270
Contrast-enhanced ultrasonography reveals a lower cortical perfusion and a decreased renal flow reserve in hypertensive patients.
Damianaki A, Hendriks-Balk M, Brito W, Polychronopoulou E, Theiler K, Maillard M, Maurer J, Eugster P, Pruijm M, Wuerzner G
Nephrol Dial Transplant. 2024 Jan 31;39(2):242-250
Antiretroviral Drug Exposure and Response in Obese and Morbidly Obese People With Human Immunodeficiency Virus (HIV): A Study Combining Modelling and Swiss HIV Cohort Data.
Berton M, Bettonte S, Stader F, Decosterd L, Tarr PE, Livio F, Cavassini M, Braun DL, Kusejko K, Hachfeld A, Bernasconi E, Calmy A, Schmid P, Battegay M, Marzolini C, Swiss HIV Cohort Study
Clin Infect Dis. 2024 Jan 25;78(1):98-110
[Pharmacovigilance. Withdrawal and rebound effects: not just with psychotropic drugs].
Marouf R, Chtioui H, Girardin FR, Buclin T, Diezi L
Rev Med Suisse. 2024 Jan 17;20(856-7):96-101
Guidance for the Interpretation of Long-Acting Cabotegravir and Rilpivirine Concentrations Based on Real-World Therapeutic Drug Monitoring Data and Documented Failures.
Thoueille P, Cavassini M, Guidi M, Buclin T, Girardin FR, Decosterd LA, Marzolini C
Open Forum Infect Dis. 2024 Feb;11(2):ofae023
Real-world trough concentrations and effectiveness of long-acting cabotegravir and rilpivirine: a multicenter prospective observational study in Switzerland.
Thoueille P, Saldanha SA, Schaller F, Choong E, Munting A, Cavassini M, Braun D, Günthard HF, Kusejko K, Surial B, Furrer H, Rauch A, Rougemont M, Ustero P, Calmy A, Stöckle M, Marzolini C, Di Benedetto C, Bernasconi E, Schmid P, Piso RJ, Andre P, Girardin FR, Guidi M, Buclin T, Decosterd LA, Swiss HIV Cohort Study
Lancet Reg Health Eur. 2024 Jan;36:100793
The Deleterious Consequences of a Nonsteroidal Anti-inflammatory Drug in an Eisenmenger Patient.
Grütter S, Haefliger D, Wuerzner G, Yerly P, Bouchardy J, Rutz T
CJC Pediatr Congenit Heart Dis. 2024 Feb;3(1):11-13
Rue du Bugnon 17
CHUV, Centre hospitalier universitaire vaudois
CH-1011 Lausanne, Vaud, Suisse
+41 21 314 4260
Rue du Bugnon 17
CHUV, Centre hospitalier universitaire vaudois
CH-1011 Lausanne, Vaud, Suisse
+41 21 314 4260