Publications
Publications sélectionnées
Flavones, Flavonols, and Glycosylated Derivatives-Impact on <i>Candida albicans</i> Growth and Virulence, Expression of <i>CDR1</i> and <i>ERG11</i>, Cytotoxicity.
Ivanov M, Kannan A, Stojković DS, Glamočlija J, Calhelha RC, Ferreira ICFR, Sanglard D, Soković M
Pharmaceuticals (Basel). 2020 Dec 30;14(1)
New Data on the <i>In Vitro</i> Activity of Fenticonazole against Fluconazole-Resistant <i>Candida</i> Species.
Cacaci M, Menchinelli G, Torelli R, Sanglard D, Sanguinetti M, Posteraro B
Antimicrob Agents Chemother. 2020 Nov 17;64(12)
Identification and Characterization of Mediators of Fluconazole Tolerance in <i>Candida albicans</i>.
Delarze E, Brandt L, Trachsel E, Patxot M, Pralong C, Maranzano F, Chauvel M, Legrand M, Znaidi S, Bougnoux ME, d'Enfert C, Sanglard D
Front Microbiol. 2020;11:591140
Emerging echinocandin-resistant Candida albicans and glabrata in Switzerland.
Coste AT, Kritikos A, Li J, Khanna N, Goldenberger D, Garzoni C, Zehnder C, Boggian K, Neofytos D, Riat A, Bachmann D, Sanglard D, Lamoth F, Fungal Infection Network of Switzerland (FUNGINOS).
Infection. 2020 Oct;48(5):761-766
Signaling Pathways Governing the Caspofungin Paradoxical Effect in Aspergillus fumigatus.
Papon N, Morio F, Sanglard D
mBio. 2020 Aug 18;11(4)
Single yeast cell nanomotions correlate with cellular activity.
Willaert RG, Vanden Boer P, Malovichko A, Alioscha-Perez M, Radotić K, Bartolić D, Kalauzi A, Villalba MI, Sanglard D, Dietler G, Sahli H, Kasas S
Sci Adv. 2020 Jun;6(26):eaba3139
Large-scale genome mining allows identification of neutral polymorphisms and novel resistance mutations in genes involved in Candida albicans resistance to azoles and echinocandins.
Sitterlé E, Coste AT, Obadia T, Maufrais C, Chauvel M, Sertour N, Sanglard D, Puel A, D'Enfert C, Bougnoux ME
J Antimicrob Chemother. 2020 Apr 1;75(4):835-848
Machine Learning Approach for <i>Candida albicans</i> Fluconazole Resistance Detection Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.
Delavy M, Cerutti L, Croxatto A, Prod'hom G, Sanglard D, Greub G, Coste AT
Front Microbiol. 2019;10:3000
Comparative Genomics for the Elucidation of Multidrug Resistance in Candida lusitaniae.
Kannan A, Asner SA, Trachsel E, Kelly S, Parker J, Sanglard D
mBio. 2019 Dec 24;10(6)
Condition-specific series of metabolic sub-networks and its application for gene set enrichment analysis.
Tran VDT, Moretti S, Coste AT, Amorim-Vaz S, Sanglard D, Pagni M
Bioinformatics. 2019 Jul 1;35(13):2258-2266
Link between Heat Shock Protein 90 and the Mitochondrial Respiratory Chain in the Caspofungin Stress Response of Aspergillus fumigatus.
Aruanno M, Bachmann D, Sanglard D, Lamoth F
Antimicrob Agents Chemother. 2019 Jul;63(7)
Persistence of <i>Candida albicans</i> in the Oral Mucosa Induces a Curbed Inflammatory Host Response That Is Independent of Immunosuppression.
Kirchner FR, Littringer K, Altmeier S, Tran VDT, Schönherr F, Lemberg C, Pagni M, Sanglard D, Joller N, LeibundGut-Landmann S
Front Immunol. 2019;10:330
Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches.
Sanglard D
PLoS Pathog. 2019 Jan;15(1):e1007478
Implications of the EUCAST Trailing Phenomenon in Candida tropicalis for the <i>In Vivo</i> Susceptibility in Invertebrate and Murine Models.
Astvad KMT, Sanglard D, Delarze E, Hare RK, Arendrup MC
Antimicrob Agents Chemother. 2018 Dec;62(12)
Worldwide emergence of resistance to antifungal drugs challenges human health and food security.
Fisher MC, Hawkins NJ, Sanglard D, Gurr SJ
Science. 2018 May 18;360(6390):739-742
Azole Resistance of Environmental and Clinical Aspergillus fumigatus Isolates from Switzerland.
Riat A, Plojoux J, Gindro K, Schrenzel J, Sanglard D
Antimicrob Agents Chemother. 2018 Apr;62(4)
A standardized toolkit for genetic engineering of CTG clade yeasts.
Defosse TA, Courdavault V, Coste AT, Clastre M, de Bernonville TD, Godon C, Vandeputte P, Lanoue A, Touzé A, Linder T, Droby S, Rosa CA, Sanglard D, d'Enfert C, Bouchara JP, Giglioli-Guivarc'h N, Papon N
J Microbiol Methods. 2018 Jan;144:152-156
Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens.
Dorsaz S, Snäkä T, Favre-Godal Q, Maudens P, Boulens N, Furrer P, Ebrahimi SN, Hamburger M, Allémann E, Gindro K, Queiroz EF, Riezman H, Wolfender JL, Sanglard D
Antimicrob Agents Chemother. 2017 Sep;61(9)
Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata.
Vella A, De Carolis E, Mello E, Perlin DS, Sanglard D, Sanguinetti M, Posteraro B
Sci Rep. 2017 Aug 22;7(1):9099
Comparative Genomics of Two Sequential <i>Candida glabrata</i> Clinical Isolates.
Vale-Silva L, Beaudoing E, Tran VDT, Sanglard D
G3 (Bethesda). 2017 Aug 7;7(8):2413-2426
Red-Shifted Firefly Luciferase Optimized for <i>Candida albicans In vivo</i> Bioluminescence Imaging.
Dorsaz S, Coste AT, Sanglard D
Front Microbiol. 2017;8:1478
High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines.
Filipuzzi I, Cotesta S, Perruccio F, Knapp B, Fu Y, Studer C, Pries V, Riedl R, Helliwell SB, Petrovic KT, Movva NR, Sanglard D, Tao J, Hoepfner D
PLoS Genet. 2016 Nov;12(11):e1006374
Identification of Triterpenoids from Schefflera systyla, Odontadenia puncticulosa and Conostegia speciosa and In Depth Investigation of Their in vitro and in vivo Antifungal Activities
Favre-Godal, Q., Dorsaz, S., Marcourt, L., Bertini, V., Dormia, E., Michellod, E., Voinesco, F., Gupta, M., Gindro, K., Sanglard, D., Queiroz, E., and Wolfender, J.-L. (2016)
Journal of the Brazilian Chemical Society
Dual action antifungal small molecule modulates multidrug efflux and TOR signaling.
Shekhar-Guturja T, Gunaherath GM, Wijeratne EM, Lambert JP, Averette AF, Lee SC, Kim T, Bahn YS, Tripodi F, Ammar R, Döhl K, Niewola-Staszkowska K, Schmitt L, Loewith RJ, Roth FP, Sanglard D, Andes D, Nislow C, Coccetti P, Gingras AC, Heitman J, Gunatilak
Nat Chem Biol. 2016 Oct;12(10):867-75
Identification of Aspergillus fumigatus multidrug transporter genes and their potential involvement in antifungal resistance.
Meneau I, Coste AT, Sanglard D
Med Mycol. 2016 Aug 1;54(6):616-27
Pleiotropic effects of the vacuolar ABC transporter MLT1 of Candida albicans on cell function and virulence.
Khandelwal NK, Kaemmer P, Förster TM, Singh A, Coste AT, Andes DR, Hube B, Sanglard D, Chauhan N, Kaur R, d'Enfert C, Mondal AK, Prasad R
Biochem J. 2016 Jun 1;473(11):1537-52
Biological Characterization and in Vivo Assessment of the Activity of a New Synthetic Macrocyclic Antifungal Compound.
Deodato D, Maccari G, De Luca F, Sanfilippo S, Casian A, Martini R, D'Arezzo S, Bonchi C, Bugli F, Posteraro B, Vandeputte P, Sanglard D, Docquier JD, Sanguinetti M, Visca P, Botta M
J Med Chem. 2016 Apr 28;59(8):3854-66
Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.
Healey KR, Zhao Y, Perez WB, Lockhart SR, Sobel JD, Farmakiotis D, Kontoyiannis DP, Sanglard D, Taj-Aldeen SJ, Alexander BD, Jimenez-Ortigosa C, Shor E, Perlin DS
Nat Commun. 2016 Mar 29;7:11128
Emerging Threats in Antifungal-Resistant Fungal Pathogens.
Sanglard D
Front Med (Lausanne). 2016;3:11
A New Endogenous Overexpression System of Multidrug Transporters of Candida albicans Suitable for Structural and Functional Studies.
Banerjee A, Khandelwal NK, Sanglard D, Prasad R
Front Microbiol. 2016;7:261
Upregulation of the Adhesin Gene EPA1 Mediated by PDR1 in Candida glabrata Leads to Enhanced Host Colonization.
Vale-Silva LA, Moeckli B, Torelli R, Posteraro B, Sanguinetti M, Sanglard D
mSphere. 2016 Mar-Apr;1(2)
Antifungal Quinoline Alkaloids from Waltheria indica.
Cretton S, Dorsaz S, Azzollini A, Favre-Godal Q, Marcourt L, Ebrahimi SN, Voinesco F, Michellod E, Sanglard D, Gindro K, Wolfender JL, Cuendet M, Christen P
J Nat Prod. 2016 Feb 26;79(2):300-7
Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.
Nishikawa JL, Boeszoermenyi A, Vale-Silva LA, Torelli R, Posteraro B, Sohn YJ, Ji F, Gelev V, Sanglard D, Sanguinetti M, Sadreyev RI, Mukherjee G, Bhyravabhotla J, Buhrlage SJ, Gray NS, Wagner G, Näär AM, Arthanari H
Nature. 2016 Feb 25;530(7591):485-9
Novel Approaches for Fungal Transcriptomics from Host Samples.
Amorim-Vaz S, Sanglard D
Front Microbiol. 2015;6:1571
Acquired Multidrug Antifungal Resistance in Candida lusitaniae during Therapy.
Asner SA, Giulieri S, Diezi M, Marchetti O, Sanglard D
Antimicrob Agents Chemother. 2015 Dec;59(12):7715-22
Activity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms.
Sanglard D, Coste AT
Antimicrob Agents Chemother. 2016 Jan;60(1):229-38
RNA Enrichment Method for Quantitative Transcriptional Analysis of Pathogens In Vivo Applied to the Fungus Candida albicans.
Amorim-Vaz S, Tran Vdu T, Pradervand S, Pagni M, Coste AT, Sanglard D
MBio. 2015 Sep 22;6(5):e00942-15
Stepwise emergence of azole, echinocandin and amphotericin B multidrug resistance in vivo in Candida albicans orchestrated by multiple genetic alterations.
Jensen RH, Astvad KM, Silva LV, Sanglard D, Jørgensen R, Nielsen KF, Mathiasen EG, Doroudian G, Perlin DS, Arendrup MC
J Antimicrob Chemother. 2015 Sep;70(9):2551-5
Tipping the balance both ways: drug resistance and virulence in Candida glabrata.
Vale-Silva LA, Sanglard D
FEMS Yeast Res. 2015 Jun;15(4):fov025
Examining the virulence of Candida albicans transcription factor mutants using Galleria mellonella and mouse infection models.
Amorim-Vaz S, Delarze E, Ischer F, Sanglard D, Coste AT
Front Microbiol. 2015;6:367
Adaptation of a Gaussia princeps Luciferase reporter system in Candida albicans for in vivo detection in the Galleria mellonella infection model.
Delarze E, Ischer F, Sanglard D, Coste AT
Virulence. 2015;6(7):684-93
Mechanisms of Antifungal Drug Resistance.
Cowen LE, Sanglard D, Howard SJ, Rogers PD, Perlin DS
Cold Spring Harb Perspect Med. 2014 Nov 10;5(7):a019752
Pivotal role for a tail subunit of the RNA polymerase II mediator complex CgMed2 in azole tolerance and adherence in Candida glabrata.
Borah S, Shivarathri R, Srivastava VK, Ferrari S, Sanglard D, Kaur R
Antimicrob Agents Chemother. 2014 Oct;58(10):5976-86
Comprehensive approach for the detection of antifungal compounds using a susceptible strain of Candida albicans and confirmation of in vivo activity with the Galleria mellonella model.
Favre-Godal Q, Dorsaz S, Queiroz EF, Conan C, Marcourt L, Wardojo BP, Voinesco F, Buchwalder A, Gindro K, Sanglard D, Wolfender JL
Phytochemistry. 2014 Sep;105:68-78
Resistance of Candida spp. to antifungal drugs in the ICU: where are we now?
Maubon D, Garnaud C, Calandra T, Sanglard D, Cornet M
Intensive Care Med. 2014 Sep;40(9):1241-55
Molecular mechanisms of action of herbal antifungal alkaloid berberine, in Candida albicans.
Dhamgaye S, Devaux F, Vandeputte P, Khandelwal NK, Sanglard D, Mukhopadhyay G, Prasad R
PLoS One. 2014;9(8):e104554
Novel role of a family of major facilitator transporters in biofilm development and virulence of Candida albicans.
Shah AH, Singh A, Dhamgaye S, Chauhan N, Vandeputte P, Suneetha KJ, Kaur R, Mukherjee PK, Chandra J, Ghannoum MA, Sanglard D, Goswami SK, Prasad R
Biochem J. 2014 Jun 1;460(2):223-35
Distinct roles of Candida albicans drug resistance transcription factors TAC1, MRR1, and UPC2 in virulence.
Lohberger A, Coste AT, Sanglard D
Eukaryot Cell. 2014 Jan;13(1):127-42
Fermentative 2-carbon metabolism produces carcinogenic levels of acetaldehyde in Candida albicans.
Marttila E, Bowyer P, Sanglard D, Uittamo J, Kaihovaara P, Salaspuro M, Richardson M, Rautemaa R
Mol Oral Microbiol. 2013 Aug;28(4):281-91
Novel Macrocyclic Amidinoureas: Potent Non-Azole Antifungals Active against Wild-Type and Resistant Candida Species.
Sanguinetti M, Sanfilippo S, Castagnolo D, Sanglard D, Posteraro B, Donzellini G, Botta M
ACS Med Chem Lett. 2013 Sep 12;4(9):852-7
Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals.
Eddouzi J, Parker JE, Vale-Silva LA, Coste A, Ischer F, Kelly S, Manai M, Sanglard D
Antimicrob Agents Chemother. 2013 Jul;57(7):3182-93
Gain-of-function mutations in PDR1, a regulator of antifungal drug resistance in Candida glabrata, control adherence to host cells.
Vale-Silva L, Ischer F, Leibundgut-Landmann S, Sanglard D
Infect Immun. 2013 May;81(5):1709-20
Milbemycins: more than efflux inhibitors for fungal pathogens.
Silva LV, Sanguinetti M, Vandeputte P, Torelli R, Rochat B, Sanglard D
Antimicrob Agents Chemother. 2013 Feb;57(2):873-86
Characterization of a new clinical yeast species, Candida tunisiensis sp. nov., isolated from a strain collection from Tunisian hospitals.
Eddouzi J, Hofstetter V, Groenewald M, Manai M, Sanglard D
J Clin Microbiol. 2013 Jan;51(1):31-9
Identification and functional characterization of Rca1, a transcription factor involved in both antifungal susceptibility and host response in Candida albicans.
Vandeputte P, Pradervand S, Ischer F, Coste AT, Ferrari S, Harshman K, Sanglard D
Eukaryot Cell. 2012 Jul;11(7):916-31
Azole resistance by loss of function of the sterol Δ⁵,⁶-desaturase gene (ERG3) in Candida albicans does not necessarily decrease virulence.
Vale-Silva LA, Coste AT, Ischer F, Parker JE, Kelly SL, Pinto E, Sanglard D
Antimicrob Agents Chemother. 2012 Apr;56(4):1960-8
Species-specific recognition of Aspergillus fumigatus by Toll-like receptor 1 and Toll-like receptor 6.
Rubino I, Coste A, Le Roy D, Roger T, Jaton K, Boeckh M, Monod M, Latgé JP, Calandra T, Bochud PY
J Infect Dis. 2012 Mar 15;205(6):944-54
Sensing of mammalian IL-17A regulates fungal adaptation and virulence.
Zelante T, Iannitti RG, De Luca A, Arroyo J, Blanco N, Servillo G, Sanglard D, Reichard U, Palmer GE, Latgè JP, Puccetti P, Romani L
Nat Commun. 2012 Feb 21;3:683
In vitro effect of malachite green on Candida albicans involves multiple pathways and transcriptional regulators UPC2 and STP2.
Dhamgaye S, Devaux F, Manoharlal R, Vandeputte P, Shah AH, Singh A, Blugeon C, Sanglard D, Prasad R
Antimicrob Agents Chemother. 2012 Jan;56(1):495-506
Antifungal resistance and new strategies to control fungal infections.
Vandeputte P, Ferrari S, Coste AT
Int J Microbiol. 2012;2012:713687
The bZIP transcription factor Rca1p is a central regulator of a novel CO₂ sensing pathway in yeast.
Cottier F, Raymond M, Kurzai O, Bolstad M, Leewattanapasuk W, Jiménez-López C, Lorenz MC, Sanglard D, Váchová L, Pavelka N, Palková Z, Mühlschlegel FA
PLoS Pathog. 2012 Jan;8(1):e1002485
Interrogation of related clinical pan-azole-resistant Aspergillus fumigatus strains: G138C, Y431C, and G434C single nucleotide polymorphisms in cyp51A, upregulation of cyp51A, and integration and activation of transposon Atf1 in the cyp51A promoter.
Albarrag AM, Anderson MJ, Howard SJ, Robson GD, Warn PA, Sanglard D, Denning DW
Antimicrob Agents Chemother. 2011 Nov;55(11):5113-21
ADH1 expression inversely correlates with CDR1 and CDR2 in Candida albicans from chronic oral candidosis in APECED (APS-I) patients.
Siikala E, Bowyer P, Richardson M, Saxen H, Sanglard D, Rautemaa R
FEMS Yeast Res. 2011 Sep;11(6):494-8
Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A.
Florio AR, Ferrari S, De Carolis E, Torelli R, Fadda G, Sanguinetti M, Sanglard D, Posteraro B
BMC Microbiol. 2011 May 11;11:97
Loss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in mice.
Ferrari S, Sanguinetti M, De Bernardis F, Torelli R, Posteraro B, Vandeputte P, Sanglard D
Antimicrob Agents Chemother. 2011 May;55(5):1852-60
Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae.
Alcazar-Fuoli L, Mellado E, Cuenca-Estrella M, Sanglard D
Med Mycol. 2011 Apr;49(3):276-84
Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata.
Ferrari S, Sanguinetti M, Torelli R, Posteraro B, Sanglard D
PLoS One. 2011 Mar 9;6(3):e17589
Doxorubicin induces drug efflux pumps in Candida albicans.
Kofla G, Turner V, Schulz B, Storch U, Froelich D, Rognon B, Coste AT, Sanglard D, Ruhnke M
Med Mycol. 2011 Feb;49(2):132-42
In vivo systematic analysis of Candida albicans Zn2-Cys6 transcription factors mutants for mice organ colonization.
Vandeputte P, Ischer F, Sanglard D, Coste AT
PLoS One. 2011;6(10):e26962
Persistent Candida albicans colonization and molecular mechanisms of azole resistance in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients.
Siikala E, Rautemaa R, Richardson M, Saxen H, Bowyer P, Sanglard D
J Antimicrob Chemother. 2010 Dec;65(12):2505-13
Genetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infection.
MacCallum DM, Coste A, Ischer F, Jacobsen MD, Odds FC, Sanglard D
Antimicrob Agents Chemother. 2010 Apr;54(4):1476-83
PAP1 [poly(A) polymerase 1] homozygosity and hyperadenylation are major determinants of increased mRNA stability of CDR1 in azole-resistant clinical isolates of Candida albicans.
Manoharlal R, Gorantala J, Sharma M, Sanglard D, Prasad R
Microbiology. 2010 Feb;156(Pt 2):313-26
Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation.
Sanglard D, Coste A, Ferrari S
FEMS Yeast Res. 2009 Oct;9(7):1029-50
Functional analysis of cis- and trans-acting elements of the Candida albicans CDR2 promoter with a novel promoter reporter system.
Coste AT, Crittin J, Bauser C, Rohde B, Sanglard D
Eukaryot Cell. 2009 Aug;8(8):1250-67
Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence.
Ferrari S, Ischer F, Calabrese D, Posteraro B, Sanguinetti M, Fadda G, Rohde B, Bauser C, Bader O, Sanglard D
PLoS Pathog. 2009 Jan;5(1):e1000268
Divergent functions of three Candida albicans zinc-cluster transcription factors (CTA4, ASG1 and CTF1) complementing pleiotropic drug resistance in Saccharomyces cerevisiae.
Coste AT, Ramsdale M, Ischer F, Sanglard D
Microbiology. 2008 May;154(Pt 5):1491-501
The ATP-binding cassette transporter-encoding gene CgSNQ2 is contributing to the CgPDR1-dependent azole resistance of Candida glabrata.
Torelli R, Posteraro B, Ferrari S, La Sorda M, Fadda G, Sanglard D, Sanguinetti M
Mol Microbiol. 2008 Apr;68(1):186-201
Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates.
Coste A, Selmecki A, Forche A, Diogo D, Bougnoux ME, d'Enfert C, Berman J, Sanglard D
Eukaryot Cell. 2007 Oct;6(10):1889-904
Variability of voriconazole plasma levels measured by new high-performance liquid chromatography and bioassay methods.
Pascual A, Nieth V, Calandra T, Bille J, Bolay S, Decosterd LA, Buclin T, Majcherczyk PA, Sanglard D, Marchetti O
Antimicrob Agents Chemother. 2007 Jan;51(1):137-43
The CRH family coding for cell wall glycosylphosphatidylinositol proteins with a predicted transglycosidase domain affects cell wall organization and virulence of Candida albicans.
Pardini G, De Groot PW, Coste AT, Karababa M, Klis FM, de Koster CG, Sanglard D
J Biol Chem. 2006 Dec 29;281(52):40399-411
Identification of promoter elements responsible for the regulation of MDR1 from Candida albicans, a major facilitator transporter involved in azole resistance.
Rognon B, Kozovska Z, Coste AT, Pardini G, Sanglard D
Microbiology. 2006 Dec;152(Pt 12):3701-22
A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans.
Coste A, Turner V, Ischer F, Morschhäuser J, Forche A, Selmecki A, Berman J, Bille J, Sanglard D
Genetics. 2006 Apr;172(4):2139-56
CRZ1, a target of the calcineurin pathway in Candida albicans.
Karababa M, Valentino E, Pardini G, Coste AT, Bille J, Sanglard D
Mol Microbiol. 2006 Mar;59(5):1429-51
A human-curated annotation of the Candida albicans genome.
Braun BR, van Het Hoog M, d'Enfert C, Martchenko M, Dungan J, Kuo A, Inglis DO, Uhl MA, Hogues H, Berriman M, Lorenz M, Levitin A, Oberholzer U, Bachewich C, Harcus D, Marcil A, Dignard D, Iouk T, Zito R, Frangeul L, Tekaia F, Rutherford K, Wang E, Munro
PLoS Genet. 2005 Jul;1(1):36-57
Azole and fungicide resistance in clinical and environmental Aspergillus fumigatus isolates.
Meneau I, Sanglard D
Med Mycol. 2005 May;43 Suppl 1:S307-11
TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.
Coste AT, Karababa M, Ischer F, Bille J, Sanglard D
Eukaryot Cell. 2004 Dec;3(6):1639-52
Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters.
Karababa M, Coste AT, Rognon B, Bille J, Sanglard D
Antimicrob Agents Chemother. 2004 Aug;48(8):3064-79
Research Book Chapters
Chapter 5: Drug Combinations as a Strategy to Potentiate Existing Antifungal Agents
Dominique Sanglard and Leah Cowen
Chapter 13: Animal Models to Study Fungal Virulence and Antifungal Drugs
Alix T. Coste and Sara Amorim-Vaz
CHUV
Rue du Bugnon 48
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+41 21 314 4056
CHUV
Rue du Bugnon 48
CH-1011 Lausanne, Suisse
+41 21 314 4056