After a PhD in Neurosciences at the University of Geneva on synaptic plasticity in the hippocampus, I worked with Prof. Fred Gage at the Salk Institute, in San Diego, one of the first labs that rediscovered the existence of adult neurogenesis. After this, I worked at Hoffmann-La-Roche and AClmmune, on Alzheimer's disease. Since 2010, I established the Tonilab at the University of Lausanne.
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For my PhD, I studied the regulation of tissue type plasminogen activator with Pr. D. Vivien and Dr. F. Docagne, at the University of Caen, France. Then, I investigated the regulation of the sumoyJation machinery in neurons and astrocytes in the lab. of Dr S. Martin, in Sophia Antipolis, Nice.
Since March 2015, I am in the Tonilab, to study the role of astrocytes in the regulation of adult neurogenesis.
During my PhD in neurosciences, at the University or Bordeaux (NutriNeuro lab), I studied the mechanisms underlying the effect of omega-3 defficiency on anxiety- and depressive-related behaviors in mice. Then I have pursued my career as a postdoctoral researcher at the EPFL (LGC lab), in which I showed that social organization in a group of inbred mice differentially affects vulnerability/resilience to both chronic social defeat and chronic restraint stress.
I joined the Tonilab in September 2017 to investigate the role of blood circulating molecules in adult neurogenesis and behavior in mice.
During my PhD (CNRS, Toulouse, France), I provided new insight into the functional relevance of adult neurogenesis in for learning and memory processes in the context of Alzheimer's disease. Between 2015 and 2017, in the laboratory of Prof. Deglon in Lausanne, Switzerland, I demonstrated that hippocampal deficits could singularly explain the memory impairment observed in Huntington's disease. In addition, with the support from the Alzheimer's Swiss Foundation, we developed novel approaches to investigate the role of astrocytes for neuronal function and cognitive performances in tauopathies.
Since December 2017, I joined the Tonilab to investigate the role of astrocytic mitochondria in synapse formation and cognition.
After my graduation in Bsc Biotechnology at the University of Paris Sud, I worked ln the iPS platform at the Institute of Gustave Roussy (France). I cultured and characterized IPSc in the context of leukemia disease. Then I worked at the Oncology Department {CHUV, Lausanne) and Ludwig Cancer Research Lausanne, where I did comparative tests of different therapeutics molecules on human tumors, which can activate and proliferate.
I joined the Tonilab in April 2018 to help with the different projects of the team.
After obtaining my bachelor in Biology at the University of Lausanne, I continued my studies in Lausanne by following a Master in Medical Biology, with a specialization in Neurosciences. I conducted my premaster work in the lab of Prof. Bernard Thorens, in the Center for lntegrative Genomics. I was working on the int1uence of postnatal overnutrition on the innervation of the arcuate nucleus of the hypothalamus.
Since May 2018, I joined the Tonilab to conduct my Master Project by working on the identifications of molecules released by astrocytes that influence adult neurogenesis, under the supervision of Dr Frédéric Cassé.
During my biomedical Master in Lausanne, I realized a first step project in the Swiss Laboratory for Doping Analyses, on circulating microRNAs as anti-doping biomarkers. Then, I decided to specialize in neurosciences
and I joined the Tonilab in May 2018, to conduct my Master main internship under the supervision or Dr. Thomas Larrieu, on the role of adult neurogenesis in the development of depressive-like behavior by high social status in mice.
After my bachelor in Biology at the University of Lausanne, I started my Master in the biomedical field with a specialization in metabolism. During my pre-master work in the lab. of Dr. Paola Bezzi, I helped characterize a new mouse model of schizophrenia at the level of astrocytes and mitochondria.
After that, I joined the Tonilab in May 2018 to perform my master work on protin homoestasis in tauopathies, under the supervision of Dr. Kevin Richetin.