Research activities led by Prof. J. Popp focus on the early biological and clinical changes associated with delirium and cognitive decline in older people. In particular, this research aims to:
The SNSF has awarded an important research grant to the project "An integrative multi-omics approach to investigate cerebral and systemic biological pathway alterations with clinical relevance in early Alzheimer's disease" led by Prof. J Popp.
The aim of this research project is to comprehensively study biological alterations in blood, cerebrospinal fluid and MRI in the early stages of Alzheimer's disease in order to better understand their relevance for cognitive deficits and psychological symptoms such as depression or apathy. In addition, new biomarker candidates to improve individual diagnosis and prognosis could be identified and validated during this project.
In addition to the University Department of Advanced Age Psychiatry (SUPAA), the University Departments of Geriatric Psychiatry in Zurich and Bern are participating in this project. The multicentric implementation of the project will facilitate the application of the results in clinical practice and strengthen the cooperation of the participating centres beyond this project.