includes Action members representing the disciplines of medicine, clinical research, basic science, genetics, and bioinformatics. They oversee the scientific objectives and refine the aims of the Action.
| Philippe Bouchard | France |
| William Colledge | United Kingdom |
| Paolo Giacobini | France |
| Jean-Pierre Hardelin | France |
| Allan Herbison | New Zealand |
| IIpo Huhtaniemi | United Kingdom |
| Robert P Millar | United Kingdom |
| Luca Persani | Italy |
| Taneli Raivio | Finland |
| Gerasimos Sykiotis | Greece |